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RN-1 dihydrochloride - ≥97%, high purity , CAS No.1781835-13-9

COA

Grade & Purity:

≥97%

Cas Number: 1781835-13-9
Molecular Weight: 452.42
PubChem CID: 90488995

In stock

Item Number

R276429

Grouped product items
SKU	Size	Availability	Price	Qty
R276429-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$137.90
R276429-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$621.90

Potent, cell-permeable LSD-1 inhibitor.

View related series

Epigenetics (1496) Histone Demethylase (97) Histone Modification (1379)

Basic Description

Synonyms	1-(4-Methylpiperazin-1-yl)-2-[[(1R,2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethenonedihydrochloride
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Potent, cell-permeable LSD-1 inhibitor (IC 50 = 70 nM). Selective for LSD-1 versus MAO-A (IC 50 = 0.51\xa0μM) and MAO-B (IC 50 = 2.79\xa0μM).\xa0Impairs long-term, but not short-term memory in mice. Brain penetrant following systemic administration.
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Note	Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

Names and Identifiers

IUPAC Name	1-(4-methylpiperazin-1-yl)-2-[[(1R,2S)-2-(4-phenylmethoxyphenyl)cyclopropyl]amino]ethanone;dihydrochloride
INCHI	InChI=1S/C23H29N3O2.2ClH/c1-25-11-13-26(14-12-25)23(27)16-24-22-15-21(22)19-7-9-20(10-8-19)28-17-18-5-3-2-4-6-18;;/h2-10,21-22,24H,11-17H2,1H3;2*1H/t21-,22+;;/m0../s1
InChIKey	WMHAFZOOUBPQRX-VSIGASKDSA-N
Smiles	CN1CCN(CC1)C(=O)CNC2CC2C3=CC=C(C=C3)OCC4=CC=CC=C4.Cl.Cl
Isomeric SMILES	CN1CCN(CC1)C(=O)CN[C@@H]2C[C@H]2C3=CC=C(C=C3)OCC4=CC=CC=C4.Cl.Cl
PubChem CID	90488995
Molecular Weight	452.42

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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