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RKRARKE - ≥98%, high purity , CAS No.82801-73-8

COA

Grade & Purity:

≥98%

Cas Number: 82801-73-8
Molecular Weight: 943.11
PubChem CID: 134097
PubChem SID: 504757027

In stock

Item Number

R276094

Grouped product items
SKU	Size	Availability	Price
R276094-1mg	1mg	3	$77.90
R276094-5mg	5mg	3	$349.90
R276094-10mg	10mg	3	$629.90
R276094-25mg	25mg	2	$1,416.90
R276094-50mg	50mg	2	$2,549.90

Competitive protein kinase G (PKG) inhibitor

Basic Description

Synonyms	AKOS024456827 \| Arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid \| cGMP Dependent Kinase Inhibitor Peptide \| L-Glutamic acid, N-(N2-(N2-(N-(N2-(N2-L-arginyl-L-lysyl)-L-arginyl)-L-alanyl)-L-arginyl)-L-lysyl)- \| MS-31758 \| (S)-2-((6S,9S,12S,15S,18S,
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Competitive protein kinase G (PKG) inhibitor. K i = 86 µM for PKG; K i = 550 µM for PKA. Potential inhibitory activity in neuronal systems.
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Peptides
        Level6 Oligopeptides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Peptides
Direct Parent	Oligopeptides
Alternative Parents	Glutamic acid and derivatives N-acyl-L-alpha-amino acids Alpha amino acid amides Alanine and derivatives N-acyl amines Fatty acids and conjugates Dicarboxylic acids and derivatives Secondary carboxylic acid amides Guanidines Amino acids Propargyl-type 1,3-dipolar organic compounds Carboxylic acids Carboximidamides Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic acyclic compounds
Substituents	Alpha-oligopeptide - Glutamic acid or derivatives - N-acyl-l-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-acyl-alpha-amino acid - Alpha-amino acid amide - Alanine or derivatives - Alpha-amino acid or derivatives - N-substituted-alpha-amino acid - Fatty acyl - Fatty acid - N-acyl-amine - Fatty amide - Dicarboxylic acid or derivatives - Amino acid - Secondary carboxylic acid amide - Guanidine - Carboxamide group - Amino acid or derivatives - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Carboxylic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504757027
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504757027
IUPAC Name	(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]pentanedioic acid
INCHI	InChI=1S/C38H74N18O10/c1-21(29(59)52-26(13-8-20-50-38(46)47)33(63)54-24(11-3-5-17-40)34(64)56-27(35(65)66)14-15-28(57)58)51-31(61)25(12-7-19-49-37(44)45)55-32(62)23(10-2-4-16-39)53-30(60)22(41)9-6-18-48-36(42)43/h21-27H,2-20,39-41H2,1H3,(H,51,61)(H,52,59)(H,53,60)(H,54,63)(H,55,62)(H,56,64)(H,57,58)(H,65,66)(H4,42,43,48)(H4,44,45,49)(H4,46,47,50)/t21-,22-,23-,24-,25-,26-,27-/m0/s1
InChIKey	OUKSKNTVYYVIMZ-DUJSLOSMSA-N
Smiles	CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(CCCN=C(N)N)N
Isomeric SMILES	C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN=C(N)N)N
PubChem CID	134097
Molecular Weight	943.11

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
H2229280	Certificate of Analysis	Jun 09, 2023	R276094
H2229293	Certificate of Analysis	Jun 09, 2023	R276094
H2229294	Certificate of Analysis	Jun 09, 2023	R276094
H2229278	Certificate of Analysis	Jun 09, 2023	R276094
H2229277	Certificate of Analysis	Jun 09, 2023	R276094

Chemical and Physical Properties

Solubility	Soluble in water
Molecular Weight	943.100 g/mol
XLogP3	-11.400
Hydrogen Bond Donor Count	17
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	36
Exact Mass	942.584 Da
Monoisotopic Mass	942.584 Da
Topological Polar Surface Area	520.000 Å²
Heavy Atom Count	66
Formal Charge	0
Complexity	1650.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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