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Risedronate Sodium - ≥98%, high purity , Farnesyl diphosphate synthase inhibitor, CAS No.115436-72-1, Farnesyl diphosphate synthase inhibitor

COA

Grade & Purity:

≥98%

Cas Number: 115436-72-1
Molecular Weight: 305.09
PubChem CID: 4194514
PubChem SID: 504762908

In stock

Item Number

R129954

Grouped product items
SKU	Size	Availability	Price
R129954-50mg	50mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$31.90
R129954-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$103.90
R129954-1g	1g	3	$309.90
R129954-5g	5g	3	$1,030.90
R129954-25g	25g	2	$3,434.90

Osteoclast-mediated bone resorption inhibitor

View related series

Parasite (997)

Basic Description

Synonyms	AC-20120 \| Acrel \| D00942 \| H11438 \| Sodium trihydrogen (1-hydroxy-2-(3-pyridyl)ethylidene)diphosphonate \| DRFDPXKCEWYIAW-UHFFFAOYSA-M \| Risedronate (sodium) \| Risedronate sodium 2.5-hydrate, European Pharmacopoeia (EP) Reference Standard \| Risedronate so
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Risedronate sodium is a pyridinyl biphosphonate which inhibits osteoclast-mediated bone resorption. Risedronate sodium is an inhibitor of FDPS.Osteoclast-mediated bone resorption inhibitor. Promotes osteoblast differentiation and reduces osteocyte apoptos
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Action Type	INHIBITOR
Mechanism of action	Farnesyl diphosphate synthase inhibitor
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Risedronate Sodium is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone. A pyridinyl biphosphonate.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Organic phosphonic acids and derivatives
    - Subclass Bisphosphonates

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Organic phosphonic acids and derivatives
Subclass	Bisphosphonates
Intermediate Tree Nodes	Not available
Direct Parent	Bisphosphonates
Alternative Parents	Pyridines and derivatives Organic phosphonic acids Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organophosphorus compounds Organooxygen compounds Organonitrogen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Bisphosphonate - Pyridine - Organophosphonic acid - Heteroaromatic compound - Organoheterocyclic compound - Organic alkali metal salt - Azacycle - Organic nitrogen compound - Organic sodium salt - Organic salt - Organic zwitterion - Organopnictogen compound - Organophosphorus compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as bisphosphonates. These are organic compounds containing two phosphonate groups linked together through a carbon atoms.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504762908
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504762908
IUPAC Name	sodium;hydroxy-(1-hydroxy-1-phosphono-2-pyridin-3-ylethyl)phosphinate
INCHI	InChI=1S/C7H11NO7P2.Na/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6;/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15);/q;+1/p-1
InChIKey	DRFDPXKCEWYIAW-UHFFFAOYSA-M
Smiles	C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)[O-].[Na+]
Isomeric SMILES	C1=CC(=CN=C1)CC(O)(P(=O)(O)O)P(=O)(O)[O-].[Na+]
WGK Germany	3
RTECS	SZ8567200
Alternate CAS	105462-24-6，329003-65-8
PubChem CID	4194514
Molecular Weight	305.09

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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6 results found

Lot Number	Certificate Type	Date	Item
K2211794	Certificate of Analysis	Aug 22, 2024	R129954
K2211802	Certificate of Analysis	Aug 22, 2024	R129954
K2211784	Certificate of Analysis	Aug 22, 2024	R129954
K2329084	Certificate of Analysis	Dec 04, 2023	R129954
K2329085	Certificate of Analysis	Dec 04, 2023	R129954
K1509087	Certificate of Analysis	May 10, 2023	R129954

Chemical and Physical Properties

Solubility	DMSO Water 2 mg/mL Ethanol；Soluble in water, insoluble in ethanol
Sensitivity	Moisture and heat sensitive
Molecular Weight	305.090 g/mol
XLogP3
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	304.983 Da
Monoisotopic Mass	304.983 Da
Topological Polar Surface Area	151.000 Å²
Heavy Atom Count	18
Formal Charge	0
Complexity	375.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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