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Riluzole (PK 26124) - ≥99%, high purity , CAS No.850608-87-6

COA COA
    Grade & Purity:
  • ≥99%
In stock
Item Number
R275242
Grouped product items
SKU Size
Availability
 Price Qty
R275242-10mg
10mg
3
$29.90
R275242-50mg
50mg
3
$87.90
R275242-250mg
250mg
1
$339.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Neuroprotective agent. Modulates glutamate transmission.

View related series
GABA Receptor (181) Ion channel (2197) Membrane Transporter/Ion Channel (1822) Neuronal Signaling (3320) Sodium Channel (211)

Basic Description

Synonyms 2-Amino-6-trifluoromethoxybenzothiazolehydrochloride
Specifications & Purity ≥99%
Biochemical and Physiological Mechanisms Biological description: A neuroprotective agent with anticonvulsant, sedative, anti anxiety, anti ischemic, and anesthetic effects. Inhibiting glutamate release, increasing glutamate absorption, blocking voltage dependent Na+channels, antagonizing NMDA re
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Benzothiazoles
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Benzothiazoles
Alternative Parents Phenol ethers  2-amino-1,3-thiazoles  Heteroaromatic compounds  Trihalomethanes  Azacyclic compounds  Primary amines  Organooxygen compounds  Organofluorides  Hydrochlorides  Hydrocarbon derivatives  Alkyl fluorides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents 1,3-benzothiazole - Phenol ether - Benzenoid - 1,3-thiazol-2-amine - Azole - Thiazole - Heteroaromatic compound - Trihalomethane - Azacycle - Alkyl fluoride - Hydrocarbon derivative - Primary amine - Halomethane - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Alkyl halide - Hydrochloride - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as benzothiazoles. These are organic compounds containing a benzene fused to a thiazole ring (a five-membered ring with four carbon atoms, one nitrogen atom and one sulfur atom).
External Descriptors Not available

Associated Targets(Human)

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NPC1 Tchem Niemann-Pick C1 protein (18985 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAB9A Tbio Ras-related protein Rab-9A (22488 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Mapk1 MAP kinase ERK2 (650 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine;hydrochloride
INCHI InChI=1S/C8H5F3N2OS.ClH/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5;/h1-3H,(H2,12,13);1H
InChIKey QEAOELIJQRYJJS-UHFFFAOYSA-N
Smiles C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N.Cl
Isomeric SMILES C1=CC2=C(C=C1OC(F)(F)F)SC(=N2)N.Cl
PubChem CID 6419992
Molecular Weight 270.66

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number Certificate Type Date Item
A2404591 Certificate of Analysis Dec 15, 2023 R275242
A2404593 Certificate of Analysis Dec 15, 2023 R275242
A2404595 Certificate of Analysis Dec 15, 2023 R275242
A2404592 Certificate of Analysis Dec 15, 2023 R275242
A2404594 Certificate of Analysis Dec 15, 2023 R275242
A2404596 Certificate of Analysis Dec 15, 2023 R275242

Chemical and Physical Properties

Solubility Soluble in DMSO to 100 mM and in water to 10 mM
Sensitivity Moisture sensitive.
Molecular Weight 270.660 g/mol
XLogP3
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 1
Exact Mass 269.984 Da
Monoisotopic Mass 269.984 Da
Topological Polar Surface Area 76.400 Ų
Heavy Atom Count 16
Formal Charge 0
Complexity 238.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Solution Calculators

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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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