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Resazurin - 10mM in DMSO, high purity , CAS No.62758-13-8

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
R425186
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R425186-1ml
1ml
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$27.90

Blue non-fluorescent dye and red fluorescent reagent

View related series
Compound libraries (12325)

Basic Description

Synonyms Resazurin sodium salt | 62758-13-8 | Resazurin sodium | 3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide, sodium salt | Diazoresorcinol (sodium) | Resazurin (sodium) | sodium;10-oxido-7-oxophenoxazin-10-ium-3-olate | sodium 7-oxido-3-oxo-3H-phenoxazine 10-oxide | 7-Hydroxy-3H-p
Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Blue non-fluorescent dye and red fluorescent reagent. Redox indicator. Reduces to fluorescent red resorufin . Cell viability assay reagent.
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Resazurin sodium salt is a blue dye used mainly as an oxidation-reduction indicator in the resazurin test for bacteria. Potentially useful to characterize metabolic activity of mitochnodria.
A dye used as an oxidation-reduction indicator in the resazurin test for bacteria. As indicator pH 3.8 (orange) to 6.5 (dark violet)

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Benzoxazines
Subclass Phenoxazines
Intermediate Tree Nodes Not available
Direct Parent Phenoxazines
Alternative Parents Phenoxides  Heteroaromatic compounds  Cyclic ketones  Oxacyclic compounds  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic zwitterions  Organic sodium salts  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Phenoxazine - Phenoxide - Benzenoid - Heteroaromatic compound - Cyclic ketone - Oxacycle - Azacycle - Organic alkali metal salt - Hydrocarbon derivative - Organic sodium salt - Organic salt - Organopnictogen compound - Organic zwitterion - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organic oxide - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as phenoxazines. These are polycyclic aromatic compounds containing a phenoxazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a 1,4-oxazine ring.
External Descriptors Not available

Associated Targets(Human)

CASP6 Tchem Caspase-6 (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
VDR Tclin Vitamin D receptor (26531 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
POLB Tchem DNA polymerase beta (23632 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CASP6 Tchem Caspase-6 (1213 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HepG2 (196354 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FEN1 Tchem Flap endonuclease 1 (12055 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCL1 Tchem Induced myeloid leukemia cell differentiation protein Mcl-1 (3820 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
POLH Tchem DNA polymerase eta (21678 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CTNNB1 Tchem Catenin beta-1 (517 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ERG Tbio Transcriptional regulator ERG (5589 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KMT2A Tchem Histone-lysine N-methyltransferase MLL (17327 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RXFP1 Tchem Relaxin receptor 1 (6345 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Mapk1 MAP kinase ERK2 (650 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pkm Pyruvate kinase isozymes M1/M2 (66 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Vero (26788 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Dengue virus type 2 NS3 protein (2214 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Npsr1 Neuropeptide S receptor (260 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PYK Pyruvate kinase (6726 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TGR Thioredoxin glutathione reductase (28579 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
glmU Bifunctional protein glmU (125 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NS1 Nonstructural protein 1 (33327 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pos-1 Cytoplasmic zinc-finger protein (1690 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
mex-5 Zinc finger protein mex-5 (1676 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CCT2 T-complex protein 1 subunit beta (5007 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name sodium;10-oxido-7-oxophenoxazin-10-ium-3-olate
INCHI InChI=1S/C12H7NO4.Na/c14-7-1-3-9-11(5-7)17-12-6-8(15)2-4-10(12)13(9)16;/h1-6,14H;/q;+1/p-1
InChIKey IVGPGQSSDLDOLH-UHFFFAOYSA-M
Smiles C1=CC2=C(C=C1[O-])OC3=CC(=O)C=CC3=[N+]2[O-].[Na+]
Isomeric SMILES C1=CC2=C(C=C1[O-])OC3=CC(=O)C=CC3=[N+]2[O-].[Na+]
WGK Germany 3
PubChem CID 112939
Molecular Weight 251.17
Beilstein 3794971

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 251.170 g/mol
XLogP3
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 0
Exact Mass 251.019 Da
Monoisotopic Mass 251.019 Da
Topological Polar Surface Area 78.100 Ų
Heavy Atom Count 18
Formal Charge 0
Complexity 427.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Citations of This Product

1. Xiaoxue Zhao, Qiyao Wang, Ting Wang, Yan Su, Caoxing Huang, Chenhuan Lai, Qiang Yong.  (2023)  Evaluation of prebiotic ability of xylo-oligosaccharide fractions with different polymerization degrees from bamboo shoot shells.  FOOD AND BIOPRODUCTS PROCESSING,     
2. Jia Liu, Su-Hang He, Hugues Lambert, Tung-Chun Lee.  (2023)  Modulation of redox reactivity of resazurin through host-guest complexation with Cucurbit[n]uril (n = 7, 8).  Frontiers in Chemistry,  11  (1295715). 
3. Hongpeng Wang, Ruibin Bai, Danqi Hu, Wenxin Chen, Zhuqian Xiao, Jun Huang, Xiufu Wan, Jian Yang, Xuelan Yu.  (2023)  Structure analysis and in vitro evaluation of probiotic properties for polysaccharides from Phellinus baumii extracted with phosphotungstic acid assistance.  LWT-FOOD SCIENCE AND TECHNOLOGY,  188  (115367). 
4. Xing Yan, Ming-Jun Zhu.  (2023)  Enhanced bioelectricity generation in thermophilic microbial fuel cell with lignocellulose as an electron donor by resazurin-mediated electron transfer.  BIORESOURCE TECHNOLOGY,  388  (129764). 
5. Fu Yao, Yao Songyang, Wang Tiankun, Lu Yongqiang, Han Huigang, Liu Xuening, Lv Dongying, Ma Xiao, Guan Shengyu, Yao Yujun, Liu Yunjie, Yu Haiying, Li Shengli, Yang Ning, Liu Guoshi.  (2023)  Effects of melatonin on rumen microorganisms and methane production in dairy cow: results from in vitro and in vivo studies.  Microbiome,  11  (1): (1-15). 
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13. Fangli Gao, Mengmeng Sun, Jie Zhang, Yi Chang, Weihua Gao, Guanglei Ma, Xiaoming Ma, Yuming Guo.  (2022)  Fenton-like reaction and glutathione depletion by chiral manganese dioxide nanoparticles for enhanced chemodynamic therapy and chemotherapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  616  (369). 
14. Xizhe Li, Bingyu Li, Ruirui Liu, Yanhua Dong, Yongxi Zhao, Yayan Wu.  (2021)  Development of pH-responsive nanocomposites with remarkably synergistic antibiofilm activities based on ultrasmall silver nanoparticles in combination with aminoglycoside antibiotics.  COLLOIDS AND SURFACES B-BIOINTERFACES,  208  (112112). 
15. Peilin Chen, Suzhen Lei, Mingyao Tong, Qing Chang, Baodong Zheng, Yi Zhang, Hongliang Zeng.  (2022)  Effect of polysaccharide fractions from Fortunella margarita on the fecal microbiota of mice and SCFA production in vitro.  Food Science and Human Wellness,  11  (97). 
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20. Qi Wei, Yue Wei, Haiwen Wu, Xiuyan Yang, Huangli Chen, Huaxin Zhang.  (2016)  Chemical Composition, Anti-oxidant, and Antimicrobial Activities of Four Saline-Tolerant Plant Seed Oils Extracted by SFC.  JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY,  93  (9): (1173-1182). 
21. Weiwen Hu, Yong Ning, Lianzhi Li, Jinming Kong, Xueji Zhang.  (2015)  Highly sensitive detection of sequence-specific DNA with morpholino-functionalized magnetic microspheres.  Analytical Methods,  (16): (6712-6717). 
22. Fangyuan Wang, Yongxin Li, Wenying Li, Qingfeng Zhang, Jian Chen, Huipeng Zhou, Cong Yu.  (2014)  A facile method for detection of alkaline phosphatase activity based on the turn-on fluorescence of resorufin.  Analytical Methods,  (15): (6105-6109). 
23. Huayang Si, Yimeng Chen, Dejun Hu, Sainan Yao, Jie Yang, Xiaodong Wen.  (2024)  A graminan type fructan from Achyranthes bidentata prevents the kidney injury in diabetic mice by regulating gut microbiota.  CARBOHYDRATE POLYMERS,  339  (122275). 
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