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Recombinant Human Thrombopoietin GMP Protein

  • Expression System: E. coli
  • Accession #: NP_000451.1
  • Protein Tag: No tag
  • Bioactivity: Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).
  • Endotoxin Concentration: <0.1 EU/μg
In stock
Item Number
rp167459-GMP
Grouped product items
SKU Size
Availability
Price Qty
rp167459-GMP-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,419.90
rp167459-GMP-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$11,359.90

GMP, ≥95% (SDS-PAGE&SEC-HPLC), Active, E. coli, No tag, 22-195 aa

Basic Description

Product Name Recombinant Human Thrombopoietin GMP Protein
Synonyms Megakaryocyte colony-stimulating factor | Megakaryocyte growth and development factor | megakaryocyte stimulating factor | MGDF | MGDFC-mpl ligand | MKCSF | MK-CSF | ML | MPL ligand | MPLLG | MGC163194 | Myeloproliferative leukemia virus oncogene ligand |
Grade ActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance
Specifications & Purity ActiBioPure™, Bioactive, GMP, Animal Free, Carrier Free, High performance, ≥95%(SDS-PAGE&SEC-HPLC)
Biochemical and Physiological Mechanisms Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Bioactivity Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).
Endotoxin Concentration <0.1 EU/μg
Expression System E. coli
Amino Acids 22-195 aa
Sequence SPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNEL
Protein Tag No tag
N-terminal Sequence Ala-Ser22-Pro-Ala-Pro-Pro-Ala-(Cys)-Asp-Leu
Accession # NP_000451.1
Predicted molecular weight 18.7 kDa
SDS-PAGE 19 kDa, under reducing conditions

Storage and Shipping

Reconstitution Reconstitute at 100-200 μg/mL in sterile, deionized water.
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage A minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -28 ℃ under sterile conditions after reconstitution. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycl

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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