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Recombinant Human SIRP beta 1/CD172b Protein, ≥95% (SDS-PAGE), high purity

  • Expression System: HEK293
  • Accession #: O00241-1
  • Protein Tag: C-His
  • Bioactivity: When Recombinant Human SIRP beta 1/CD172b is immobilized at 1 µg/mL (100 µL/well), Recombinant Human SP‑D binds with an ED50 of 0.1-0.8 μg/mL
  • Endotoxin Concentration: <0.1 EU/μg
In stock
Item Number
rp167082
Grouped product items
SKU Size
Availability
Price Qty
rp167082-10μg
10μg
≥10
$139.90
rp167082-50μg
50μg
8
$469.90
rp167082-100μg
100μg
3
$759.90
rp167082-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$4,999.90

Animal Free, ≥95% (SDS-PAGE), Active, HEK293, C-His tag, 30-371 aa

Basic Description

Product Name Recombinant Human SIRP beta 1/CD172b Protein, ≥95% (SDS-PAGE), high purity
Synonyms CD172 antigen like family member B | CD172b | CD172b antigen | DKFZp686A05192 | Signal regulatory protein beta 1 | SIRP BETA 1 | SIRP beta 1 isoform 3 | SIRPB1 | SIRP-BETA-1
Grade ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description

Purity
≥95% (SDS-PAGE)
Endotoxin level
<0.1 EU/μg
Function
The protein encoded by the SIRPß1 gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins which are known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPß1 was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications & Purity ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity ≥95% (SDS-PAGE)
Bioactivity When Recombinant Human SIRP beta 1/CD172b is immobilized at 1 µg/mL (100 µL/well), Recombinant Human SP‑D binds with an ED50 of 0.1-0.8 μg/mL
Endotoxin Concentration <0.1 EU/μg
Expression System HEK293
Amino Acids 30-371 aa
Sequence EDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAVRATPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPAGDSVSYSIHSTARVVLTRGDVHSQVICEIAHITLQGDPLRGTANLSEAIRVPPTLEVTQQPMRAENQANVTCQVSNFYPRGLQLTWLENGNVSRTETASTLIENKDGTYNWMSWLLVNTCAHRDDVVLTCQVEHDGQQAVSKSYALEISAHQKEHGSDITHEAALAPTAPLHHHHHH
Protein Tag C-His
Accession # O00241-1
Predicted molecular weight 38 kDa
SDS-PAGE 55-60 kDa, under reducing conditions

Storage and Shipping

Shape Lyophilized
Reconstitution Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -20~-80℃ for more than 1 year. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Human SIRP beta 1/CD172b Protein (rp167082) - Protein Bioactivity
When Recombinant Human SIRP beta 1/CD172b Protein (rp167082) is immobilized at 1.0 µg/mL, Recombinant Human SP‑D binds with an ED₅₀ of 0.93 μg/mL.

Recombinant Human SIRP beta 1/CD172b Protein (rp167082) - SDS-PAGE
3 μg/lane of Recombinant Human SIRP beta 1/CD172b Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 45.0 - 55.0 kDa.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404855 Certificate of Analysis Apr 26, 2024 rp167082
ZJ24F0404854 Certificate of Analysis Apr 26, 2024 rp167082
ZJ24F0404853 Certificate of Analysis Apr 26, 2024 rp167082

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