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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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rp168392-GMP-10μg
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10μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$379.90
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rp168392-GMP-50μg
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50μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,049.90
|
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rp168392-GMP-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$8,399.90
|
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GMP, ≥97% (SDS-PAGE&SEC-HPLC), Active, CHO, No tag, 311-426 aa
| Product Name | Recombinant Human/Mouse/Rat Activin A GMP Protein |
|---|---|
| Synonyms | Activin A | activin AB alpha polypeptide | Activin beta-A chain | erythroid differentiation factor | Erythroid differentiation protein | follicle-stimulating hormone-releasing protein | FSH-releasing protein | inhibin beta A chain | inhibin beta A subunit |
| Grade | ActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance |
| Specifications & Purity | ActiBioPure™, Bioactive, GMP, Animal Free, Carrier Free, High performance, ≥97%(SDS-PAGE&SEC-HPLC) |
| Biochemical and Physiological Mechanisms | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone |
| Bioactivity | Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50for this effect is 0.2-1.2 ng/mL.The specific activity of Recombinant Human/Mouse/Rat Activin A is >1000 units/mg, which is calibrated against the human Activin A WHO reference standard (NIBSC code: 91/626). |
| Endotoxin Concentration | <0.01 EU/μg |
| Expression System | CHO |
| Amino Acids | 311-426 aa |
| Sequence | GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS |
| Protein Tag | No tag |
| N-terminal Sequence | Gly311-Leu-Glu-(Cys)-Asp-Gly-Lys-Val-Asn-Ile |
| Accession # | P08476 |
| Predicted molecular weight | 13 kDa (monomer) |
| SDS-PAGE | 14 kDa, reducing conditions. 24 kDa, non-reducing conditions. |
| Reconstitution | Reconstitute at 100-500 μg/mL in sterile 4 mM HCl. |
|---|---|
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | A minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -20 ℃ under sterile conditions after reconstitution. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycl |
Starting at $139.90
Starting at $139.90