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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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rp168383-GMP-50μg
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50μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,079.90
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rp168383-GMP-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$8,639.90
|
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GMP, ≥97% (SDS-PAGE&SEC-HPLC), Active, E.coli, No tag, 29-212 aa
| Product Name | Recombinant Human IL-6 GMP Protein |
|---|---|
| Synonyms | B-cell differentiation factor | B-cell stimulatory factor 2 | BSF2 | BSF-2 | CDF | CTL differentiation factor | HSF | hybridoma growth factor | IFNB2 | IFN-beta-2 | IL6 | IL-6 | Interferon beta-2 | HGF | interleukin 6 (interferon, beta 2) | interleukin BS |
| Grade | ActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance |
| Specifications & Purity | Animal Free, Carrier Free, ActiBioPure™, Bioactive, GMP, High performance, ≥97%(SDS-PAGE&SEC-HPLC) |
| Biochemical and Physiological Mechanisms | Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induc |
| Bioactivity | Measured in a cell proliferation assay using T1165.85.2.1 mouse plasmacytoma cells. The ED50 for this effect is 0.2‑0.8 ng/mL. The specific activity of Recombinant Human IL-6 is >1.0 x 10^8 IU/mg, which is calibrated against the human IL‑6 WHO International Standard(NIBSC code: 89/548). |
| Endotoxin Concentration | <0.1 EU/μg |
| Expression System | E. coli |
| Amino Acids | 29-212 aa |
| Sequence | PVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM |
| Protein Tag | No tag |
| N-terminal Sequence | Pro29-Val-Pro-Pro-Gly-Glu-Asp-Ser-Lys-Asp |
| Accession # | P05231.1 |
| Predicted molecular weight | 20.9 kDa |
| SDS-PAGE | 20-21 kDa, under reducing conditions |
| Reconstitution | Reconstitute at 100-200 μg/mL in sterile PBS. |
|---|---|
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | A minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -20 ℃ under sterile conditions after reconstitution. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycl |