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Recombinant Human IL-4R alpha Protein

  • Accession #: P24394
  • Bioactivity: Measured by its ability to inhibit IL-4 induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 42.55 ng/mL in the presence of 20.0 ng/mL of Recombinant Human IL-4 Protein (rp147593).
  • Endotoxin Concentration: <1.0 EU/μg
In stock
Item Number
rp184044
Grouped product items
SKU Size
Availability
Price Qty
rp184044-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$159.90
rp184044-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$459.90
rp184044-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$729.90
rp184044-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$4,719.90

Animal Free, ≥95% (SDS-PAGE), Active, HEK293, C-His, 1-232 aa

Basic Description

Product Name Recombinant Human IL-4R alpha Protein
Synonyms CD124 | IL 4R alpha | IL-4 receptor subunit alpha | IL-4-binding protein | IL-4R subunit alpha | IL-4R-alpha | IL-4RA | IL4-BP | Il4r | IL4R nirs variant 1 | IL4RA | IL4RA_HUMAN | Interleukin 4 receptor | Interleukin 4 receptor alpha chain | sIL4Ralpha/pr
Grade ActiBioPure™, Animal Free, Bioactive, Carrier Free, High Performance
Specifications & Purity ActiBioPure™, Bioactive, Animal Free, Carrier Free, High Performance, ≥95%(SDS-PAGE)
Biochemical and Physiological Mechanisms Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production
Bioactivity Measured by its ability to inhibit IL-4 induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 42.55 ng/mL in the presence of 20.0 ng/mL of Recombinant Human IL-4 Protein (rp147593).
Endotoxin Concentration <1.0 EU/μg
Amino Acids 1-232 aa
Sequence MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHHHHHHH
Accession # P24394
Predicted molecular weight 24.6 kDa
SDS-PAGE 38.1-53.0 kDa, under reducing conditions; 38.1-53.0 kDa, under non-reducing conditions.

Storage and Shipping

Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -20°C for 1 year. Avoid freeze/thaw cycle.

Images

Recombinant Human IL-4R alpha Protein (rp184044) - Protein Bioactivity
Measured by its ability to inhibit IL-4 induced proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 42.55 ng/mL in the presence of 20.0 ng/mL of Recombinant Human IL-4 Protein (rp147593).

Recombinant Human IL-4R alpha Protein (rp184044) - SDS-PAGE
3 μg/lane of Recombinant Human IL-4R alpha Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 38.1-53.0 kDa.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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