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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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rp168384-GMP-50μg
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50μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,009.90
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rp168384-GMP-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$8,479.90
|
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GMP, ≥97% (SDS-PAGE&SEC-HPLC), Active, E.coli, No tag, 25-153 aa
| Product Name | Recombinant Human IL-4 GMP Protein |
|---|---|
| Synonyms | B cell growth factor 1 | BCDF | B-cell stimulatory factor 1 | BCGF1 | BCGF-1 | binetrakin | BSF1 | BSF-1 | IL4 | IL-4 | IL-4B_cell stimulatory factor 1 | IL4E12 | interleukin 4 | interleukin-4 | Lymphocyte stimulatory factor 1 | MGC79402 | pitrakinra |
| Grade | ActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance |
| Specifications & Purity | Animal Free, Carrier Free, GMP, Bioactive, ActiBioPure™, High performance, ≥97%(SDS-PAGE&SEC-HPLC) |
| Biochemical and Physiological Mechanisms | Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface express |
| Bioactivity | Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is 0.0400-0.320 ng/mL.The specific activity of GMP Recombinant Human IL-4 is >1.0x10^7 IU/mg, which is calibrated against the human IL-4 WHO International Standard (NIBSC code: 88/656). |
| Endotoxin Concentration | <0.1 EU/μg |
| Expression System | E. coli |
| Amino Acids | 25-153 aa |
| Sequence | MHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS |
| Protein Tag | No tag |
| N-terminal Sequence | Met-His25-Lys-(Cys)-Asp-Ile-Thr-Leu-Gln-GluMet-His25-Lys-(Cys)-Asp-Ile-Thr-Leu-Gln-Glu |
| Accession # | P05112.1 |
| Predicted molecular weight | 15.1 kDa |
| SDS-PAGE | 13 kDa, under reducing conditions |
| Reconstitution | Reconstitute at 500 μg/mL in PBS. |
|---|---|
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | A minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -20 ℃ under sterile conditions after reconstitution. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycl |