Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
rp168388-GMP-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,319.90
|
|
|
rp168388-GMP-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$6,599.90
|
|
GMP, ≥97% (SDS-PAGE&SEC-HPLC), Active, E.coli, No tag, 117-269 aa
| Product Name | Recombinant Human IL-1 beta/IL-1F2 GMP Protein |
|---|---|
| Synonyms | Interleukin 1 beta | catabolin | IL1 beta | IL-1 beta | IL-1 | IL1B | IL-1b | IL1-BETA | IL-1F2 | IL1F2 | interleukin 1, beta | interleukin-1 beta | preinterleukin 1 beta | pro-interleukin-1-beta | IL1beta |
| Grade | ActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance |
| Specifications & Purity | ActiBioPure™, Bioactive, GMP, Carrier Free, Animal Free, High performance, ≥97%(SDS-PAGE&SEC-HPLC) |
| Biochemical and Physiological Mechanisms | Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast |
| Bioactivity | Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. The ED50 for this effect is <12 pg/mL. The specific activity of recombinant human IL-1 beta is >5.0 x 10^7 IU/mg, which is calibrated against the human IL-1 beta WHO International Standard (NIBSC code: 86/680). |
| Endotoxin Concentration | <0.01 EU/μg |
| Expression System | E. coli |
| Amino Acids | 117-269 aa |
| Sequence | APVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS |
| Protein Tag | No tag |
| N-terminal Sequence | Ala-Pro-Val-Arg-Ser-Leu-Asn-(Cys)-Thr-Leu & Pro-Val-Arg-Ser-Leu-Asn-(Cys)-Thr-Leu-Arg |
| Accession # | P01584 |
| Predicted molecular weight | 17 kDa |
| SDS-PAGE | 17 kDa under reducing conditions. |
| Reconstitution | Reconstitute at 100-200 μg/mL in PBS. |
|---|---|
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | A minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -20 ℃ under sterile conditions after reconstitution. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycl |
Starting at $139.90
Starting at $139.90