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| SKU | Size | Availability |
Price | Qty |
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rp168359-GMP-200μg
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200μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$309.90
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rp168359-GMP-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$799.90
|
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GMP, ≥97% (SDS-PAGE&SEC-HPLC), Active, E.coli, No tag, 49-118 aa
| Product Name | Recombinant Human IGF-I/IGF-1 GMP Protein |
|---|---|
| Synonyms | Insulin-like Growth Factor I/Insulin-like Growth Factor 1 | IBP1 | IGF1 | IGF-1 | IGF1A | IGFI | IGF-I | IGF-IA | IGF-IB | insulin-like growth factor 1 (somatomedin C) | insulin-like growth factor 1 | insulin-like growth factor I | insulin-like growth fac |
| Grade | ActiBioPure™, Animal Free, Bioactive, Carrier Free, GMP, High Performance |
| Specifications & Purity | Animal Free, Carrier Free, GMP, Bioactive, ActiBioPure™, High performance, ≥97%(SDS-PAGE&SEC-HPLC) |
| Biochemical and Physiological Mechanisms | The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthe |
| Bioactivity | Measured in a serum-free cell proliferation assay using MCF7 human breast cancer cells. The ED50 for this effect is 0.3-1.5 ng/mL. The specific activity of recombinant human IGF-I/IGF-1 is >1000 IU/mg, which is calibrated against the human IGF-I/IGF-1/IGF-1 WHO International Standard (NIBSC code: 91/554). |
| Endotoxin Concentration | <0.1 EU/μg |
| Expression System | E. coli |
| Amino Acids | 49-118 aa |
| Sequence | GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA |
| Protein Tag | No tag |
| N-terminal Sequence | Gly-Pro-Glu-Thr-Leu-(Cys)-Gly-Ala-Glu-Leu |
| Accession # | P05019-1 |
| Predicted molecular weight | 7.6 kDa |
| SDS-PAGE | 8 kDa under reducing conditions. |
| Reconstitution | Reconstitute at 100 μg/mL in PBS. |
|---|---|
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | A minimum of 12 months when stored at ≤ -20 ℃ as supplied. 1 month, 2 to 8 ℃ under sterile conditions after reconstitution. 3 months, ≤ -20 ℃ under sterile conditions after reconstitution. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycl |