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Recombinant Human CD98 Protein, ≥95% (SDS-PAGE), high purity

Grade & Purity:

≥95%(SDS-PAGE)

Expression System: HEK293
Accession #: P08195-1
Protein Tag: N-His
Bioactivity: Immobilized Human CD98 Protein at 5 μg/mL (100 μL/well) can bind ITGB1 with a linear range of 20-1200 ng/mL.
Endotoxin Concentration: <0.1 EU/μg

In stock

Item Number

rp144163

Grouped product items
SKU	Size	Availability	Price
rp144163-10μg	10μg	≥10	$139.90
rp144163-50μg	50μg	8	$359.90
rp144163-100μg	100μg	3	$569.90
rp144163-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,949.90

Animal Free, ≥95% (SDS-PAGE), Active, HEK293, N-His tag, 206-630 aa

View related series

Click to view protein information: SLC3A2

Accession#:P08195 (9) CD98 (9) Gene ID:6520 (9) SLC3A2 (9)

Basic Description

Product Name	Recombinant Human CD98 Protein, ≥95% (SDS-PAGE), high purity
Synonyms	4F2 \| 4F2 cell surface antigen heavy chain \| 4F2 cell-surface antigen heavy chain \| 4F2 heavy chain \| 4F2 heavy chain antigen \| 4F2_HUMAN \| 4F2hc \| 4T2HC \| Antigen defined by monoclonal antibody 4F2 heavy chain \| Antigen identified by monoclonal antibodie
Grade	ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free
Product Description	Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier."
Specifications & Purity	ActiBioPure™, Bioactive, Animal Free, Carrier Free, Azide Free, ≥95%(SDS-PAGE)
Purity	≥95% (SDS-PAGE)
Bioactivity	Immobilized Human CD98 Protein at 5 μg/mL (100 μL/well) can bind ITGB1 with a linear range of 20-1200 ng/mL.
Endotoxin Concentration	<0.1 EU/μg
Expression System	HEK293
Species	Human
Amino Acids	206-630 aa
Sequence	HHHHHHRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFSTQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
Protein Tag	N-His
Accession #	P08195-1
Predicted molecular weight	47 kDa
SDS-PAGE	50-60 kDa, under reducing conditions

Storage and Shipping

Shape	Lyophilized
Reconstitution	Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage Temp	Store at -20°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at -20~-80℃ for more than 1 year. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Images

Protein Bioactivity: Recombinant Human CD98 Protein (rp144163)

Recombinant Human CD98 Protein (rp144163) - Protein Bioactivity
Immobilized Recombinant Human CD98 Protein (rp144163) at 5.0 μg/mL can bind ITGB1 with a linear range of 20 -1280 ng/mL. The EC₅₀ for this effect is 918.8 ng/mL.

SDS-PAGE: Recombinant Human CD98 Protein (rp144163)

Recombinant Human CD98 Protein (rp144163) - SDS-PAGE
3 μg/lane of Recombinant Human CD98 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 55 - 65 kDa.

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3 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0607446	Certificate of Analysis	Jun 28, 2024	rp144163
ZJ24F0607447	Certificate of Analysis	Jun 28, 2024	rp144163
ZJ24F0607448	Certificate of Analysis	Jun 28, 2024	rp144163

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