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Recombinant Human 14-3-3 beta/alpha Protein

  • Accession #: P31946
  • Endotoxin Concentration: <1.0 EU/μg
In stock
Item Number
rp214462
Grouped product items
SKU Size
Availability
Price Qty
rp214462-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$89.90
rp214462-50μg
50μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$269.90
rp214462-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$429.90
rp214462-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,399.90

Carrier Free, ≥90% (SDS-PAGE), E. coli, N-His, 2-246 aa

Basic Description

Product Name Recombinant Human 14-3-3 beta/alpha Protein
Synonyms 14-3-3 alpha | 14-3-3 protein beta/alpha | 1433B_HUMAN | Brain protein 14-3-3 beta isoform | GW128 | HS 1 | KCIP-1 | KCIP1 | N-terminally processed | Protein 1054 | Protein kinase C inhibitor protein 1 | YWHAA | YWHAB
Grade Carrier Free
Specifications & Purity Carrier Free, ≥90%(SDS-PAGE), See COA
Biochemical and Physiological Mechanisms Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the
Endotoxin Concentration <1.0 EU/μg
Amino Acids 2-246 aa
Sequence MHHHHHHTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN
Accession # P31946
Predicted molecular weight 28.9 kDa
SDS-PAGE 27.9 kDa, under reducing conditions; 27.5 & 28.1 & 54.3 kDa, under non-reducing conditions.

Storage and Shipping

Concentration See COA
Storage Temp Store at -20°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -20℃ for 12 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Human 14-3-3 beta/alpha Protein (rp214462) - SDS-PAGE
2 μg/lane of Recombinant Human 14-3-3 beta/alpha Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 27.9 kDa under reducing conditions and 27.5 & 28.1 & 54.3 kDa under non-reducing conditions.
14-3-3 beta/alpha can form homodimer (Uniptot: P31946).
Under non-reducing conditions, the cysteine residues of YWHAB form different disulfide bonds (Cys12-Cys214 or Cys26-Cys189), leading to structural domain rearrangements that enable the protein to adopt two distinct conformations (PMID: 15347690).

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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