Basic Description

Synonyms	RAFFINOSE \| Melitose \| D-Raffinose \| Gossypose \| d-(+)-Raffinose \| 512-69-6 \| Melitriose \| 6G-alpha-D-galactosylsucrose \| rafinose \| raflinose \| CHEBI:16634 \| Raffinose, pure \| NSC 2025 \| UNII-N5O3QU595M \| NSC 170228 \| N5O3QU595M \| AI3-19427 \| EINECS 208-146-9 \| Caryophyllene alcohol acetat
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Raffinose (Melitose, Melitriose) is a complex carbohydrate, a trisaccharide composed of galactose, fructose, and glucose. It can be broken apart into galactose and sucrose via the enzyme alpha-galactosidase.
Storage Temp	Protected from light,Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information Raffinose (Melitose, Melitriose) is a complex carbohydrate, a trisaccharide composed of galactose, fructose, and glucose. It can be broken apart into galactose and sucrose via the enzyme alpha-galactosidase.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic oxygen compounds
  - Class Organooxygen compounds
    - Subclass Carbohydrates and carbohydrate conjugates

Kingdom	Organic compounds
Superclass	Organic oxygen compounds
Class	Organooxygen compounds
Subclass	Carbohydrates and carbohydrate conjugates
Intermediate Tree Nodes	Not available
Direct Parent	Oligosaccharides
Alternative Parents	O-glycosyl compounds C-glycosyl compounds Ketals Oxanes Tetrahydrofurans Secondary alcohols Polyols Oxacyclic compounds Primary alcohols Hydrocarbon derivatives
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	Oligosaccharide - C-glycosyl compound - Glycosyl compound - O-glycosyl compound - Ketal - Oxane - Tetrahydrofuran - Secondary alcohol - Acetal - Oxacycle - Organoheterocyclic compound - Polyol - Alcohol - Primary alcohol - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as oligosaccharides. These are carbohydrates made up of 3 to 10 monosaccharide units linked to each other through glycosidic bonds.
External Descriptors	trisaccharide - raffinose family oligosaccharide
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

Homo sapiens (32628 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Syrian golden hamster (1610 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lecA PA-I galactophilic lectin (65 Activities)

Discover Target: lecA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2S,3R,4S,5R,6R)-2-[[(2R,3S,4S,5R,6R)-6-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
INCHI	InChI=1S/C18H32O16/c19-1-5-8(22)11(25)13(27)16(31-5)30-3-7-9(23)12(26)14(28)17(32-7)34-18(4-21)15(29)10(24)6(2-20)33-18/h5-17,19-29H,1-4H2/t5-,6-,7-,8+,9-,10-,11+,12+,13-,14-,15+,16+,17-,18+/m1/s1
InChIKey	MUPFEKGTMRGPLJ-ZQSKZDJDSA-N
Smiles	C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3(C(C(C(O3)CO)O)O)CO)O)O)O)O)O)O)O
Isomeric SMILES	C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O[C@]3([C@H]([C@@H]([C@H](O3)CO)O)O)CO)O)O)O)O)O)O)O
Molecular Weight	504.45
Reaxy-Rn	1694611
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1694611&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Sensitivity	light sensitive
Melt Point(°C)	118-120° C
Molecular Weight	504.400 g/mol
XLogP3	-5.800
Hydrogen Bond Donor Count	11
Hydrogen Bond Acceptor Count	16
Rotatable Bond Count	8
Exact Mass	504.169 Da
Monoisotopic Mass	504.169 Da
Topological Polar Surface Area	269.000 Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	655.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	14
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Ze-Lin Qiu, Wen-Han Yu, Wu-Shang Yang, Tong Sun, Zi-Hao Zhao, Qian-Wei Su, Bao-Ku Zhu. (2024) Ionic Hyperbranched Poly(amido-amine)-Incorporated Nanofiltration Membranes for High-Efficiency Dye Desalination. LANGMUIR, 40 (1): (915–926).
2. Yuqi Cui, Huachun Lan, Qingwen Tang, Xiaoqiang An, Huijuan Liu, Jiuhui Qu. (2024) C3N4-interlayer-mediated interfacial polymerization of homopolymer nanofiltration membranes for efficient water purification. JOURNAL OF MEMBRANE SCIENCE, 693 (122350).
3. Yanling Liu, Qihang Cen, Kaiming Fan, Airan Hu, Xu Yuan, Shengji Xia. (2024) Enhancing nanofiltration membrane selectivity between mineral salts and organic pollutants by sulfonic acid functionalization for drinking water treatment. JOURNAL OF MEMBRANE SCIENCE, 693 (122358).
4. Mei-Ling Liu, Lan Hong, Yueming Zhu, Razi Epsztein, Ting Shi, Yuanxia Sun, Zhijun Xu, Shi-Peng Sun, Weihong Xing. (2023) Constructing biocatalytic nanochannel membranes for unidirectional isomer conversion and separation. AICHE JOURNAL, 69 (11): (e18187).
5. Qiao Qian, Zhang Xiang, Yan Zhenhao, Hou Chuanyu, Zhang Juanli, He Yong, Zhao Na, Yan Shujie, Gong Youping, Li Qian. (2023) The use of machine learning to predict the effects of cryoprotective agents on the GelMA-based bioinks used in extrusion cryobioprinting. Bio-Design and Manufacturing, 6 (4): (464-477).
6. Yanrui Wang, Hailin Chang, Shu Jiang, Jialong Chen, Jinlong Wang, Heng Liang, Guibai Li, Xiaobin Tang. (2023) An efficient co-solvent tailoring interfacial polymerization for nanofiltration: enhanced selectivity and mechanism. JOURNAL OF MEMBRANE SCIENCE, 677 (121615).
7. Ke Chen, Jingyun Zhang, Xing Liu, Peiyuan Zhang, Wenlong Yue, Zhiqiang Cai. (2023) High Molecular Weight α-Galactosidase from the Novel Strain Aspergillus sp. D-23 and Its Hydrolysis Performance. Processes, 11 (1): (255).
8. Xin Liu, Hao Cai, Minjie Niu, Hui Yu, Mengqing Wang, Hui Zhu, Gang Cao, Ke Pei, Yu Duan, Jiantao Song. (2023) An integrated strategy of secondary metabolomics and glycomics to investigate multi-component variations in wine-processing of medicinal herbs and functional foods: A case study on Fructus Corni. Arabian Journal of Chemistry, 16 (104525).
9. Huihui Yang, Xiaosen Bai, Baolong Feng, Qinghua Wang, Li Meng, Fengzhong Wang, Yutang Wang. (2023) Application of Molecular Transformer approach for predicting the potential reactions to generate advanced glycation end products in infant formula. FOOD CHEMISTRY, 407 (135143).
10. Yunhao Li, Shuhao Wang, HengYu Li, Dandan Liu, Yan Jin, Guodong Kang, Yiming Cao. (2023) Polyamide nanofiltration membranes with rigid–flexible microstructures for high-efficiency Mg2+/Li+ separation. SEPARATION AND PURIFICATION TECHNOLOGY, 306 (122552).
11. Zhongbao Ma, Long-Fei Ren, Diwen Ying, Jinping Jia, Jiahui Shao. (2023) Dual-layer Janus charged nanofiltration membranes constructed by sequential electrospray polymerization for efficient water softening. CHEMOSPHERE, 310 (136929).
12. Kaiming Fan, Yanling Liu, Xiaoping Wang, Peng Cheng, Shengji Xia. (2022) Comparison of polyamide, polyesteramide and polyester nanofiltration membranes: properties and separation performance. SEPARATION AND PURIFICATION TECHNOLOGY, 297 (121579).
13. Jun Xiang, Huan Li, Yunhao Hei, Guiying Tian, Lei Zhang, Penggao Cheng, Jianping Zhang, Na Tang. (2022) Preparation of highly permeable electropositive nanofiltration membranes using quaternized polyethyleneimine for dye wastewater treatment. Journal of Water Process Engineering, 48 (102831).
14. Hao Zhang, Fei Xie, Zhang Zhao, Noor Ul Afsar, Fangmeng Sheng, Liang Ge, Xingya Li, Xiwang Zhang, Tongwen Xu. (2022) Novel Poly(ester amide) Membranes with Tunable Crosslinked Structures for Nanofiltration. ACS Applied Materials & Interfaces, 14 (8): (10782–10792).
15. Ming-Jian Tang, Mei-Ling Liu, Lu Li, Guo-Jiang Su, Xiang-Yu Yan, Can Ye, Shi-Peng Sun, Weihong Xing. (2022) Solvation-amination-synergy that neutralizes interfacially polymerized membranes for ultrahigh selective nanofiltration. AICHE JOURNAL, 68 (6): (e17602).
16. Weilin Zhang, Jianqiang Wang, Xiaolan Geng, Li Liu, Fu Liu. (2022) Electrosprayed polyamide nanofiltration membrane with uniform and tunable pores for sub-nm precision molecule separation. SEPARATION AND PURIFICATION TECHNOLOGY, 282 (120131).
17. Chao Yang, Ya Li, Mengying Long, Pengfei Yang, Yafei Li, Yu Zheng, Runnan Zhang, Yanlei Su, Hong Wu, Zhongyi Jiang. (2022) Ultrathin nanofiltration membrane assembled by polyethyleneimine-grafted graphene quantum dots. JOURNAL OF MEMBRANE SCIENCE, 642 (119944).
18. Wen Zhang, Xuan Zhang. (2021) Effective inhibition of gypsum using an ion–ion selective nanofiltration membrane pretreatment process for seawater desalination. JOURNAL OF MEMBRANE SCIENCE, 632 (119358).
19. Ze-Lin Qiu, Li-Feng Fang, Yu-Jie Shen, Wen-Han Yu, Bao-Ku Zhu, Claus Hélix-Nielsen, Wenjing Zhang. (2021) Ionic Dendrimer Based Polyamide Membranes for Ion Separation. ACS Nano, 15 (4): (7522–7535).
20. Yu-Jie Shen, Qing-Ran Kong, Li-Feng Fang, Ze-Lin Qiu, Bao-Ku Zhu. (2021) Construction of covalently-bonded tannic acid/polyhedral oligomeric silsesquioxanes nanochannel layer for antibiotics/salt separation. JOURNAL OF MEMBRANE SCIENCE, 623 (119044).
21. Zhu Wenju, Hao Shuaishuai, Yang Mingyang, Cheng Bowen, Zhang Jimei. (2020) A synergistic flame retardant of glycosyl cross-linking boron acid and ammonium salt of phytic acid to enhance durable flame retardancy of cotton fabrics. CELLULOSE, 27 (16): (9699-9710).
22. Yi Wang, Chaoqin Han, Lan Yu, Jiangling Wu, Yuanhong Min, Juan Tan, Yannan Zhao, Pu Zhang. (2020) Etching-controlled suppression of fluorescence resonance energy transfer between nitrogen-doped carbon dots and Ag nanoprisms for glucose assay and diabetes diagnosis. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 242 (118713).
23. Zhenhua Lü, Zhongwei Guo, Kaifei Zhang, Sanchuan Yu, Meihong Liu, Congjie Gao. (2020) Separation and anti-dye-deposition properties of polyamide thin-film composite membrane modified via surface tertiary amination followed by zwitterionic functionalization. JOURNAL OF MEMBRANE SCIENCE, 604 (118063).
24. Zhou Ruolin, Ren Zhiqing, Ye Jun, Fan Yawei, Liu Xiaoru, Yang Jianyuan, Deng Ze-Yuan, Li Jing. (2019) Fermented Soybean Dregs by Neurospora crassa: a Traditional Prebiotic Food. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 189 (2): (608-625).
25. Yang Hongmei, Su Rui, Wishnok John S., Liu Ning, Chen Changbao, Liu Shuying, Tannenbaum Steven R.. (2019) Magnetic silica nanoparticles for use in matrix-assisted laser desorption ionization mass spectrometry of labile biomolecules such as oligosaccharides, amino acids, peptides and nucleosides. MICROCHIMICA ACTA, 186 (2): (1-8).
26. Chun-Er Lin, Li-Feng Fang, Shi-Yuan Du, Zhi-Kan Yao, Bao-Ku Zhu. (2019) A novel positively charged nanofiltration membrane formed via simultaneous cross-linking/quaternization of poly(m-phenylene isophthalamide)/polyethyleneimine blend membrane. SEPARATION AND PURIFICATION TECHNOLOGY, 212 (101).
27. Li-Feng Fang, Ming-Yong Zhou, Liang Cheng, Bao-Ku Zhu, Hideto Matsuyama, Shuaifei Zhao. (2019) Positively charged nanofiltration membrane based on cross-linked polyvinyl chloride copolymer. JOURNAL OF MEMBRANE SCIENCE, 572 (28).
28. Chun-Er Lin, Ming-Yong Zhou, Wei-Song Hung, Bao-Ku Zhu, Kueir-Rarn Lee, Li-Ping Zhu, Li-Feng Fang. (2018) Ultrathin nanofilm with tailored pore size fabricated by metal-phenolic network for precise and rapid molecular separation. SEPARATION AND PURIFICATION TECHNOLOGY, 207 (435).
29. Xin Kong, Ze-Lin Qiu, Chun-Er Lin, You-Zhi Song, Bao-Ku Zhu, Li-Ping Zhu, Xiu-Zhen Wei. (2017) High permselectivity hyperbranched polyester/polyamide ultrathin films with nanoscale heterogeneity. Journal of Materials Chemistry A, 5 (17): (7876-7884).
30. Zhen Qin, Shaoqing Yang, Liming Zhao, Xin You, Qiaojuan Yan, Zhengqiang Jiang. (2016) *Catalytic Mechanism of a Novel Glycoside Hydrolase Family 16 “Elongating” β-Transglycosylase . JOURNAL OF BIOLOGICAL CHEMISTRY, 292** (5): (1666-1678).
31. Xi Quan Cheng, Yuyan Liu, Zhanhu Guo, Lu Shao. (2015) Nanofiltration membrane achieving dual resistance to fouling and chlorine for “green” separation of antibiotics. JOURNAL OF MEMBRANE SCIENCE, 493 (156).
32. Pei-Hong Fan, Mei-Tong Zang, Jie Xing. (2014) Oligosaccharides composition in eight food legumes species as detected by high-resolution mass spectrometry. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 95 (11): (2228-2236).
33. Qing-li Zhu, Rong Shao, Rui Dong, Zhi Yun. (2014) An integrated approach for obtaining biodiesel, sterols, gossypol, and raffinose from cottonseed on a biorefinery concept. ENERGY, 70 (149).
34. Meihong Liu,Qingyuan He,Kaifei Zhang,Zhongwei Guo,Zhenhua Lü,Sanchuan Yu,Congjie Gao. (2020-04-26) Carbodiimide-assisted zwitterionic modification of poly(piperazine amide) thin-film composite membrane for enhanced separation and anti-depositing performances to cationic/anionic dye aqueous solutions.. Journal of hazardous materials, 396 (122582-122582).
35. Yunhao Li, Haijun Yu, Lixin Li, Yanfang Liu, Guodong Kang, Xinmiao Liang, Yiming Cao. (2025) Advanced lithium extraction nanofiltration membrane with fast transport channels via competitive diffusion and reaction of rigid electropositive phenylbiguanide molecules. JOURNAL OF MEMBRANE SCIENCE, 713 (123362).
36. Wan-Ting Lin, Jia-Wen Yu, Ping Fu, Wan-Long Li, Zi-Lu Zhang, Xiao-Wei Luo, Zhi-Kang Xu, Ling-Shu Wan. (2025) Anionic surfactant assisted interfacial polymerization enables thermally resistant nanofiltration membranes. JOURNAL OF MEMBRANE SCIENCE, 723 (123936).
37. Yumeng Xie, Jing Ren, Peng Liu, Junfeng Zheng, Zhaohuan Mai, Yanyan Liu, Xuewu Zhu, Xin Li, Daliang Xu, Heng Liang. (2025) Fabrication of green xylose-based nanofiltration membrane with enhanced performance and chlorine resistance. DESALINATION, 593 (118243).
38. Wei Wang, Jiarong Zhu, Yizhou Wang, Liangkun Long, Qunying Lin, Jing Wang, Shaojun Ding. (2025) Functional characterization of two GH27 ɑ-galactosidases from Penicillium parvum 4–14 and their differential capabilities upon plant biomass degradation. CARBOHYDRATE RESEARCH, 551 (109428).
39. Zhiwei Sun, Liping Liu, Ruiguo Li, Xiangying Zhao, Jianjun Liu, Jiaxiang Zhang. (2025) Improved nutritional composition and flavor of mung bean yogurt through fermentation with Lactiplantibacillus plantarum SF28. Food Bioscience, (106338).
40. Gao Xuerui, Li Ping, Qin Yuan, Bai Chengling, Gu Zhengyang, Yu Shuili. (2024) Negative rejection phenomenon in the mixed salt nanofiltration: Law and mechanism. DESALINATION, 583 (117667).
41. SunHongzheng , HanLongsen , GuoYueshuai , AnHuiqing , WangBing , ZhangXiangzheng , LiJiashuo , JiangYingtong , WangYue , SunGuangyi , ZhuShuai , TangShoubin , GeJuan , ChenMinjian , GuoXuejiang , WangQiang. (2024) The global phosphorylation landscape of mouse oocytes during meiotic maturation. EMBO JOURNAL,

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Raffinose - 10mM in DMSO, high purity , CAS No.512-69-6