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R-(-)-Deprenyl Hydrochloride - 10mM in Water, high purity , CAS No.14611-52-0, Monoamine oxidase B inhibitor

    Grade & Purity:
  • 10mM in Water
In stock
Item Number
R421689
Grouped product items
SKU Size
Availability
Price Qty
R421689-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$174.90

MAO-B selective inhibitor

View related series
Compound libraries (12325)

Basic Description

Synonyms Selegiline hydrochloride | 14611-52-0 | Selegiline Hcl | Eldepryl | Zelapar | l-Deprenyl hydrochloride | (-)-Deprenyl hydrochloride | Jumex hydrochloride | Eldepryl hydrochloride | Ensam | (-)-Deprenil hydrochloride | (-)-E-250 hydrochloride | L-Deprenyl | Plurimen | (R)-N-Methyl-N-
Specifications & Purity 10mM in Water
Biochemical and Physiological Mechanisms R(-)-Deprenyl hydrochloride is the hydrochloride salt preparation of R(-)-Deprenyl, an inhibitor of MAO-B (monoamine oxidase-B) which demonstrates extensive neuroprotective effects shown to be uncorrelated with MAO-B inhibiting activity. R(-)-Deprenyl dem
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type INHIBITOR
Mechanism of action Monoamine oxidase B inhibitor
Product Description

R-(-)-Deprenyl Hydrochloride is a selective inhibitor of monoamine oxidase B (MAO-B)

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Phenethylamines
Intermediate Tree Nodes Not available
Direct Parent Amphetamines and derivatives
Alternative Parents Phenylpropanes  Aralkylamines  Trialkylamines  Acetylides  Organopnictogen compounds  Hydrochlorides  Hydrocarbon derivatives  
Molecular Framework Aromatic homomonocyclic compounds
Substituents Amphetamine or derivatives - Phenylpropane - Aralkylamine - Tertiary aliphatic amine - Tertiary amine - Acetylide - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as amphetamines and derivatives. These are organic compounds containing or derived from 1-phenylpropan-2-amine.
External Descriptors hydrochloride - terminal acetylenic compound

Associated Targets(Human)

MAOB Tclin Amine oxidase [flavin-containing] B (2 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HepG2 (196354 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
POLI Tchem DNA polymerase iota (116820 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ABCC4 Tchem Multidrug resistance-associated protein 4 (785 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Mapk1 MAP kinase ERK2 (650 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Pseudomonas aeruginosa (123386 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Escherichia coli (133304 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name (2R)-N-methyl-1-phenyl-N-prop-2-ynylpropan-2-amine;hydrochloride
INCHI InChI=1S/C13H17N.ClH/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13;/h1,5-9,12H,10-11H2,2-3H3;1H/t12-;/m1./s1
InChIKey IYETZZCWLLUHIJ-UTONKHPSSA-N
Smiles CC(CC1=CC=CC=C1)N(C)CC#C.Cl
Isomeric SMILES C[C@H](CC1=CC=CC=C1)N(C)CC#C.Cl
WGK Germany 3
RTECS DA0292500
PubChem CID 26758
Molecular Weight 223.74

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 223.740 g/mol
XLogP3
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 1
Rotatable Bond Count 4
Exact Mass 223.113 Da
Monoisotopic Mass 223.113 Da
Topological Polar Surface Area 3.200 Ų
Heavy Atom Count 15
Formal Charge 0
Complexity 195.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 1
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Solution Calculators

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