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QX77 - 98%, high purity , CAS No.1798331-92-6

COA

Grade & Purity:

≥98%

Cas Number: 1798331-92-6
Molecular Weight: 300.74
PubChem CID: 118129505
PubChem SID: 504772854

In stock

Item Number

Q413637

Grouped product items
SKU	Size	Availability	Price
Q413637-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$122.90
Q413637-10mg	10mg	3	$204.90
Q413637-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$459.90
Q413637-50mg	50mg	3	$674.90
Q413637-100mg	100mg	2	$1,214.90

View related series

Autophagy (1917)

Basic Description

Synonyms	N-[4-(7-Chloro-2H-1,4-benzoxazin-3-yl)phenyl]acetamide \| N-(4-(7-Chloro-2H-benzo[b][1,4]oxazin-3-yl)phenyl)acetamide \| QX 77 \| QX-77
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	QX77 is a chaperone-mediated autophagy (CMA) activator derived from the atypical retinoid AR7 that activates CMA by antagonizing retinoic acid receptor-α (RARα) signaling. QX77 rescues defective trafficking & lysosomal localization of the CMA receptor LAM
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information QX77 is a novel activator ofchaperone-mediated autophagy (CMA). QX77 induces the up-regulation of Rab11 expression and up-regulates LAMP2A expression. Product description： QX77 is a chaperone-mediated autophagy (CMA) activator.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Benzoxazines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Benzoxazines
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Benzoxazines
Alternative Parents	Acetanilides N-acetylarylamines Alkyl aryl ethers Aryl chlorides Acetamides Secondary carboxylic acid amides Ketimines Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organochlorides Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Benzoxazine - Acetanilide - N-acetylarylamine - Anilide - N-arylamide - Alkyl aryl ether - Benzenoid - Monocyclic benzene moiety - Aryl halide - Aryl chloride - Acetamide - Secondary carboxylic acid amide - Ketimine - Carboxamide group - Oxacycle - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Ether - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Imine - Carbonyl group - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as benzoxazines. These are organic compounds containing a benzene fused to an oxazine ring (a six-membered aliphatic ring with four carbon atoms, one oxygen atom, and one nitrogen atom).
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504772854
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504772854
IUPAC Name	N-[4-(7-chloro-2H-1,4-benzoxazin-3-yl)phenyl]acetamide
INCHI	InChI=1S/C16H13ClN2O2/c1-10(20)18-13-5-2-11(3-6-13)15-9-21-16-8-12(17)4-7-14(16)19-15/h2-8H,9H2,1H3,(H,18,20)
InChIKey	PYCTUCLCTVWILY-UHFFFAOYSA-N
Smiles	CC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=C(C=C3)Cl)OC2
Isomeric SMILES	CC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=C(C=C3)Cl)OC2
PubChem CID	118129505
Molecular Weight	300.74

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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3 results found

Lot Number	Certificate Type	Date	Item
G2208231	Certificate of Analysis	Apr 03, 2025	Q413637
G2208183	Certificate of Analysis	Apr 03, 2025	Q413637
G2208230	Certificate of Analysis	Apr 03, 2025	Q413637

Chemical and Physical Properties

Molecular Weight	300.740 g/mol
XLogP3	2.900
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	300.067 Da
Monoisotopic Mass	300.067 Da
Topological Polar Surface Area	50.700 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	419.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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