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Quipazine dimaleate - ≥99%, high purity , CAS No.150323-78-7

COA

Grade & Purity:

≥99%

Cas Number: 150323-78-7
Molecular Weight: 445.43
PubChem CID: 6420043
PubChem SID: 488195750

In stock

Item Number

Q274905

Grouped product items
SKU	Size	Availability	Price
Q274905-50mg	50mg	3	$61.90
Q274905-100mg	100mg	2	$111.90
Q274905-250mg	250mg	2	$237.90
Q274905-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$427.90

5-HT receptor agonist

View related series

Class A GPCR (4138) Virus (1811)

Basic Description

Synonyms	HMS2096L16 \| 2-(1-Piperazinyl)quinoline Dimaleate; 2-(1-Piperazinyl)quinoline (Z)-2-Butenedioate (1:2) \| HMS3411K14 \| SR-01000075574-1 \| AKOS024458588 \| Quipazine (dimaleate) \| HMS1569L16 \| SR-01000075574-7 \| Prestwick_905 \| Quipazinedimaleate \| MS-28022
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	5-HT receptor agonist, shows some selectivity at 5-HT 3 (EC 50 = 24 nM). Displays antidepressant and anorectic effect. Also promotes cellular proliferation.
Storage Temp	Room temperature,Desiccated
Shipped In	Normal
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Diazinanes
    - Subclass Piperazines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Diazinanes
Subclass	Piperazines
Intermediate Tree Nodes	Not available
Direct Parent	Pyridinylpiperazines
Alternative Parents	N-arylpiperazines Aminoquinolines and derivatives Dialkylarylamines Aminopyridines and derivatives Unsaturated fatty acids Imidolactams Dicarboxylic acids and derivatives Benzenoids Heteroaromatic compounds Dialkylamines Carboxylic acids Azacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Not available
Substituents	Pyridinylpiperazine - N-arylpiperazine - Aminoquinoline - Quinoline - Dialkylarylamine - Aminopyridine - Dicarboxylic acid or derivatives - Pyridine - Fatty acyl - Fatty acid - Imidolactam - Benzenoid - Unsaturated fatty acid - Heteroaromatic compound - Carboxylic acid derivative - Carboxylic acid - Secondary aliphatic amine - Azacycle - Secondary amine - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Amine - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Carbonyl group - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as pyridinylpiperazines. These are compounds containing a pyridinylpiperazine skeleton, which consists of a pyridine linked (not fused) to a piperazine by a bond by a single bond that is not part of a ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

U2OS (164939 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PMP22 Tbio Peripheral myelin protein 22 (699 Activities)

Discover Target: PMP22

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HEK-293T (167025 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

nfo Endonuclease 4 (425 Activities)

Discover Target: nfo

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488195750
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488195750
IUPAC Name	(Z)-but-2-enedioic acid;2-piperazin-1-ylquinoline
INCHI	InChI=1S/C13H15N3.2C4H4O4/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16;25-3(6)1-2-4(7)8/h1-6,14H,7-10H2;21-2H,(H,5,6)(H,7,8)/b;2*2-1-
InChIKey	VAOSOCRJSSWBEQ-SPIKMXEPSA-N
Smiles	C1CN(CCN1)C2=NC3=CC=CC=C3C=C2.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
Isomeric SMILES	C1NCCN(C1)C2=NC3=CC=CC=C3C=C2.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O
PubChem CID	6420043
Molecular Weight	445.43

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
E2322110	Certificate of Analysis	Jul 10, 2024	Q274905
E2322109	Certificate of Analysis	Mar 20, 2024	Q274905
E2322229	Certificate of Analysis	Mar 20, 2024	Q274905
E2322220	Certificate of Analysis	Mar 20, 2024	Q274905
E2322111	Certificate of Analysis	Mar 07, 2024	Q274905
E2322113	Certificate of Analysis	Mar 07, 2024	Q274905

Chemical and Physical Properties

Solubility	Soluble in water to 100 mM
Molecular Weight	445.400 g/mol
XLogP3
Hydrogen Bond Donor Count	5
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	5
Exact Mass	445.149 Da
Monoisotopic Mass	445.149 Da
Topological Polar Surface Area	177.000 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	344.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	2
Covalently-Bonded Unit Count	3

Alternative Products

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