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Pyridoxine - 10mM in DMSO, high purity , CAS No.65-23-6

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
P425300
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Price Qty
P425300-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$240.90

Basic Description

Synonyms pyridoxine | 65-23-6 | vitamin B6 | Pyridoxol | Pyridoxin | Gravidox | 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine | Adermine | Hydoxin | Pyridoxolum | 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl- | 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol | 5-Hydroxy-6-methyl-3,4-pyridi
Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Pyridoxine (Vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate.
Storage Temp Protected from light,Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats.
A form of vitamin B6

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Pyridines and derivatives
Subclass Pyridoxines
Intermediate Tree Nodes Not available
Direct Parent Pyridoxines
Alternative Parents Methylpyridines  Hydroxypyridines  Heteroaromatic compounds  Azacyclic compounds  Primary alcohols  Organopnictogen compounds  Organonitrogen compounds  Hydrocarbon derivatives  Aromatic alcohols  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Pyridoxine - Methylpyridine - Hydroxypyridine - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Aromatic alcohol - Primary alcohol - Organooxygen compound - Organonitrogen compound - Alcohol - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as pyridoxines. These are pyridoxal derivatives in which the carbaldehyde group at position 2 of the pyridoxal moiety is replaced by a hydroxymethyl group.
External Descriptors a vitamin B6

Associated Targets(Human)

F2 Tclin Thrombin (11687 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Homo sapiens (32628 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDXK Tbio Pyridoxal kinase (263 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasma (328 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cenchrus americanus (77 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
INCHI InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3
InChIKey LXNHXLLTXMVWPM-UHFFFAOYSA-N
Smiles CC1=NC=C(C(=C1O)CO)CO
Isomeric SMILES CC1=NC=C(C(=C1O)CO)CO
WGK Germany 3
RTECS UV1300000
Alternate CAS 58-56-0
PubChem CID 1054
Molecular Weight 169.18

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Sensitivity light sensitive
Melt Point(°C) 159-162°C
Molecular Weight 169.180 g/mol
XLogP3 -0.800
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 2
Exact Mass 169.074 Da
Monoisotopic Mass 169.074 Da
Topological Polar Surface Area 73.600 Ų
Heavy Atom Count 12
Formal Charge 0
Complexity 142.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

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2. Luo Jialun, Jiang Cheng, Zhao Jihua, Zhao Luyao, Zheng Peizhu, Fang Jian.  (2023)  Hierarchical tungsten-doped bimetallic selenides nanosheets arrays/nickel foam composite electrode as efficient gallic acid electrochemical sensor.  MICROCHIMICA ACTA,  190  (4): (1-13). 
3. Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su.  (2023)  Development of an oil-sealed anaerobic fermentation process for high production of γ-aminobutyric acid with Lactobacillus brevis isolated by directional colorimetric screening.  BIOCHEMICAL ENGINEERING JOURNAL,  194  (108893). 
4. Yuan Kaisong, Huang Rui, Gong Kaishuo, Xiao Ziyi, Chen Jialin, Cai Siyao, Shen Jiayi, Xiong Zuer, Lin Zhexuan.  (2023)  Smartphone-based hand-held polarized light microscope for on-site pharmaceutical crystallinity characterization.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (18): (4401-4410). 
5. Tong Chen, Shuya Wang, Xufang Zong, Bingxiang Li, Ye Shu, Xinyuan Di, Wanning Zhu, Guangsan Song, Jun Jiang.  (2023)  Preparation and application of sulfated lily polysaccharide bridged polyhedral oligomeric silsesquioxane hybrid organosilicas as stationary phase.  JOURNAL OF CHROMATOGRAPHY A,  1691  (463822). 
6. Xijuan Tu, Yunmin Tao, Jiaxu Chen, Chunping Du, Qian Jin, Yuchang He, Ji Yang, Shaokang Huang, Wenbin Chen.  (2022)  Dipicolinic Acid-Tb3+/Eu3+ Lanthanide Fluorescence Sensor Array for Rapid and Visual Discrimination of Botanical Origin of Honey.  Foods,  11  (21): (3388). 
7. Nanjun Li, Chongyang Wang, Liangjun Chen, Cui Ye, Yongwu Peng.  (2022)  Ultrathin Covalent Organic Framework Nanosheets/Ti3C2Tx-Based Photoelectrochemical Biosensor for Efficient Detection of Prostate-Specific Antigen.  MOLECULES,  27  (19): (6732). 
8. Weng Chunyue, Mi Zheyan, Li Meijing, Qin Haibin, Hu Zhongce, Liu Zhiqiang, Zheng Yuguo, Wang Yuanshan.  (2022)  Improvement of S-adenosyl-L-methionine production in Saccharomyces cerevisiae by atmospheric and room temperature plasma-ultraviolet compound mutagenesis and droplet microfluidic adaptive evolution.  3 Biotech,  12  (9): (1-15). 
9. Xiuling Ji, Suping Wang, Yiyong Luo, Xiaotian Yuan, Yunlin Wei, Qi Zhang, Kunhao Qin, Yujiao Tu.  (2021)  Green synthesis of weissella-derived fluorescence carbon dots for microbial staining, cell imaging and dual sensing of vitamin B12 and hexavalent chromium.  DYES AND PIGMENTS,  184  (108818). 
10. Naiyi Yin, Zeliang Han, Huili Du, Pengfei Wang, Yunpeng Li, Xiaochen Chen, Guoxin Sun, Yanshan Cui, Zhengyi Hu.  (2020)  Effect of dietary vitamins in oral bioaccessibility of lead in contaminated soils based on the physiologically based extraction test.  SCIENCE OF THE TOTAL ENVIRONMENT,  747  (141299). 
11. Siliang Liu, Chunyu Liu, Yu Ren, Shangqi Kuang, Chengcheng Zhou, Hongxing Cai, Zhihai Yao.  (2020)  Fluorescence spectra of nutrients in chicken and skin under baking conditions.  OPTIK,  218  (164795). 
12. Shi-Qi Zhang, Jing Li, Lin Li, Xiaoting Yuan, Li Xu, Zhi-guo Shi.  (2020)  Fast separation of water-soluble vitamins by hydrophilic interaction liquid chromatography based on submicrometer flow-through silica microspheres.  FOOD CHEMISTRY,  307  (125531). 
13. Hui He, Pir Muhammad, Zhanchen Guo, Qiling Peng, Haifeng Lu, Zhen Liu.  (2019)  Controllably prepared molecularly imprinted core-shell plasmonic nanostructure for plasmon-enhanced fluorescence assay.  BIOSENSORS & BIOELECTRONICS,  146  (111733). 
14. Mengling Lin, Yingjie Guo, Zhiyong Liang, Xuesong Zhao, Jianan Chen, Yilin Wang.  (2019)  Simple and fast determination of biothiols using Fe3+-3, 3′, 5, 5′-tetramethylbenzidine as a colorimetric probe.  MICROCHEMICAL JOURNAL,  147  (319). 
15. Zhenping Liu, Mingliang Jin, Jieping Cao, Ruiwen Niu, Pengfei Li, Guofu Zhou, Ying Yu, Albert van den Berg, Lingling Shui.  (2018)  Electrochemical sensor integrated microfluidic device for sensitive and simultaneous quantification of dopamine and 5-hydroxytryptamine.  SENSORS AND ACTUATORS B-CHEMICAL,  273  (873). 
16. Huihui Li, Wei Liu, Fengyuan Zhang, Xinyue Zhu, Liqiu Huang, Haixia Zhang.  (2018)  Highly Selective Fluorescent Probe Based on Hydroxylation of Phenylboronic Acid Pinacol Ester for Detection of Tyrosinase in Cells.  ANALYTICAL CHEMISTRY,  90  (1): (855–858). 
17. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang.  (2018)  Hydrophilic polymeric monoliths containing choline phosphate for separation science applications.  ANALYTICA CHIMICA ACTA,  999  (184). 
18. Meihui Fan, Guowen Zhang, Junhui Pan, Deming Gong.  (2017)  An inhibition mechanism of dihydromyricetin on tyrosinase and the joint effects of vitamins B6, D3 or E.  Food & Function,  (7): (2601-2610). 
19. Houmei Liu, Jia Chen, Zhan Li, Makoto Takafuji, Hirotaka Ihara, Hongdeng Qiu.  (2017)  A new route for synthesis of N-methylimidazolium-grafted silica stationary phase and reevaluation in hydrophilic interaction liquid chromatography.  TALANTA,  164  (137). 
20. Yuliang Li, Xiaojia Lu, Qi Zhu, Rong Huang, Jing Hu, Hongbin Yang, Yiliang Yao.  (2016)  Phase behavior of quaternary aqueous two-phase systems: Influence factors and extraction mechanism study.  FLUID PHASE EQUILIBRIA,  430  (101). 
21. Daofan Ma, Xiaofeng Jiang, Guoqiang Wei, Chunying Zhu.  (2015)  Volumetric and Viscometric Studies of Amino Acids in Vitamin B6 Aqueous Solutions at Various Temperatures.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,  60  (5): (1279–1290). 
22. Zifei Wang, Zhipeng Wang, Hui Zhang, Xuemin Duan, Jingkun Xu, Yangping Wen.  (2015)  Electrochemical sensing application of poly(acrylic acid modified EDOT-co-EDOT):PSS and its inorganic nanocomposite with high soaking stability, adhesion ability and flexibility.  RSC Advances,  (16): (12237-12247). 
23. Cheng Xiao-Dong, Peng Xi-Tian, Yu Qiong-Wei, Yuan Bi-Feng, Feng Yu-Qi.  (2013)  Preparation of a Novel Amino-Phosphate Zwitterionic Stationary Phase for Hydrophilic Interaction Chromatography.  CHROMATOGRAPHIA,  76  (23): (1569-1576). 
24. Xi-Tian Peng, Tao Liu, Shu-Xian Ji, Yu-Qi Feng.  (2013)  Preparation of a novel carboxyl stationary phase by “thiol-ene” click chemistry for hydrophilic interaction chromatography.  JOURNAL OF SEPARATION SCIENCE,  36  (16): (2571-2577). 
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29. Chenyue Kang, Caihong Zhang, Yan Zhang, Guomei Zhang, Shaomin Shuang.  (2024)  Dual-emission ratio fluorescent probe based on carbon dots and copper-silver bimetallic nanoclusters for visual and fluorescent detection of ciprofloxacin.  MICROCHEMICAL JOURNAL,  202  (110810). 
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34. Chunyan Liu, Yanjuan Liu, Yuefei Zhang, Wei Chen, Sheng Tang.  (2024)  Synergistic expression of ZIF-67 and amphiphilic polymer hydrogel in multi-mode liquid chromatographic separation.  SEPARATION AND PURIFICATION TECHNOLOGY,  349  (127827). 
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