JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

This is a demo store. No orders will be fulfilled.

Account

Settings

Language

྾

Home
Small Molecules & Compound Libraries
Signaling Pathways
Metabolic Enzyme/Protease
Endogenous Metabolite
Pyridoxal 5-Phosphate Monohydrate - 10mM in DMSO, high purity , CAS No.41468-25-1

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Pyridoxal 5-Phosphate Monohydrate - 10mM in DMSO, high purity , CAS No.41468-25-1

5 Citations

COA

Grade & Purity:

10mM in DMSO

Cas Number: 41468-25-1
Molecular Weight: 265.16
Beilstein Registry Number: 234749
EC Number: MFCD00149414
PubChem CID: 38882

In stock

Item Number

P423880

Grouped product items
SKU	Size	Availability	Price	Qty
P423880-1ml	1ml	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$69.90

Vitamin B6 metabolite.

View related series

Compound libraries (12325) Metabolite (5307)

Basic Description

Synonyms	PLP \| (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate;hydrate \| Pyridoxal 5'-phosphate monohydrate \| Pyridoxal 5-phosphate monohydrate \| (4-Formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate hydrate(1:x) \| Tardoxal \| 3-
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Vitamin B6 metabolite that acts as a coenzyme in transamination reactions by forming a Schiff-base linkage with lysine groups on aminotransferase. Also serves as a coenzyme in some decarboxylation and deamination reactions. Can modify lysyl and valyl resi
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Pyridoxal-5’-phosphate monohydrate is a vitamin B6 metabolite that can modify lysyl and valyl residues in proteins. It has the ability to inhibit purinergic receptors and intracellular influx of Ca2+. Pyridoxal-5’-phosphate monohydrate can modify peptides and suppress their precursor ionization efficiency. Research shows that pyridoxal-5'-phosphate-dependent enzymes can be inhibited by cycloserine. A vitamin B6 metabolite that can modify lysyl and valyl residues in proteins.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyridines and derivatives
    - Subclass Pyridine carboxaldehydes

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyridines and derivatives
Subclass	Pyridine carboxaldehydes
Intermediate Tree Nodes	Not available
Direct Parent	Pyridoxals and derivatives
Alternative Parents	Monoalkyl phosphates Methylpyridines Hydroxypyridines Aryl-aldehydes Vinylogous acids Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Pyridoxal - Aryl-aldehyde - Monoalkyl phosphate - Hydroxypyridine - Methylpyridine - Organic phosphoric acid derivative - Phosphoric acid ester - Alkyl phosphate - Vinylogous acid - Heteroaromatic compound - Azacycle - Organopnictogen compound - Aldehyde - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as pyridoxals and derivatives. These are compounds containing a pyridoxal moiety, which consists of a pyridine ring substituted at positions 2,3,4, and 5 by a methyl group, a hydroxyl group, a carbaldehyde group, and a hydroxymethyl group, respectively.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate;hydrate
INCHI	InChI=1S/C8H10NO6P.H2O/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14;/h2-3,11H,4H2,1H3,(H2,12,13,14);1H2
InChIKey	CEEQUQSGVRRXQI-UHFFFAOYSA-N
Smiles	CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O.O
Isomeric SMILES	CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O.O
WGK Germany	2
RTECS	UV1208000
Molecular Weight	265.16
Beilstein	234749
Reaxy-Rn	11305661
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11305661&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Sensitivity	Light & Air Sensitive.
Melt Point(°C)	143 °C
Molecular Weight	265.160 g/mol
XLogP3
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	265.035 Da
Monoisotopic Mass	265.035 Da
Topological Polar Surface Area	118.000 Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	292.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Liu Jianming, Zhang Han, Xu Yingying, Meng Hao, Zeng An-Ping. (2023) Turn air-captured CO2 with methanol into amino acid and pyruvate in an ATP/NAD(P)H-free chemoenzymatic system. Nature Communications, 14 (1): (1-12).
2. Junli Guo, Lingling Yang, Huijie Xu, Chenxi Zhao, Zhenqing Dai, Zhida Gao, Yanyan Song. (2019) Biomineralization-Driven Ion Gate in TiO2 Nanochannel Arrays for Cell H2S Sensing. ANALYTICAL CHEMISTRY, 91 (21): (13746–13751).
3. Chaoqiang Wu, Xin Zhang, Wei Liu, Chengyong Wang, Qianqian Jiang, Feifei Chen, Quanzhen Liu, Fei Cao, Gaowei Zheng, Alei Zhang, Kequan Chen. (2024) Biocatalytic Synthesis of Two Furan-Based Amino Compounds 2-Acetyl-4-aminofuran and 3-Acetylamino-5-(α-aminoethyl)-furan from Chitin Resources. ACS Sustainable Chemistry & Engineering, 12 (30): (11145-11154).
4. Wang Minyu, Chu Weihua. (2024) Dencichine attenuates the virulence of Fusobacterium nucleatum by targeting hydrogen sulfide-producing enzyme. INTERNATIONAL MICROBIOLOGY, (1-8).
5. Kuirong Feng, Lingxin Meng, Jingmei Xu, Pengyun Zhao, Na Li, Jinxuan Lei. (2024) Introduction of Bifunctionalized UIO-66-NH2 for Highly Conductive and Long-Term Stable Fluorene-Based Sulfonated Poly(aryl ether ketone sulfone) PEMs. ACS Applied Polymer Materials, 6 (17): (10916-10926).

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.