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| SKU | Size | Availability |
Price | Qty |
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P276150-1mg
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1mg |
2
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$84.90
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P276150-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$274.90
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Endogenous\xa0prostaglandin
| Synonyms | 15-hydroxy-9-oxoprosta-10,13-dienoate | ALPROSTADIL IMPURITY A [EP IMPURITY] | 15a-Hydroxy-9-oxo-10,13E-prostadienoic acid | 15-hydroxy-9-oxoprosta-10,13-dienoic acid | BRD-K04010869-001-02-6 | 3-Cyclopentene-1-heptanoic acid, 2-(3-hydroxy-1-octenyl)-5-ox |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Endogenous prostaglandin with diverse biological actions including anti-hypertensive, anti-inflammatory, anti-viral and anti-cancer properties.Prostaglandin A1 (PGA1) boosts the expression of human liver-specific cytochrome P450 4F3B (CYP4F3B) and stimula |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information . Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. Prostaglandin A1(PGA1) belongs to the class of cyclopentenone prostaglandin. PGA1 is generated by the dehydration of prostaglandin E1 (PGE1). Prostaglandins (PG) are hormones present in many tissues and organs. They are long chain polyunsaturated fatty acids. PGA1 is a cyclopentenone molecule. Application: Prostaglandin A1(PGA1) has been used to activate Ca2+ channel of human sperm (CatSper). |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Fatty Acyls |
| Subclass | Eicosanoids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Prostaglandins and related compounds |
| Alternative Parents | Long-chain fatty acids Fatty alcohols Hydroxy fatty acids Secondary alcohols Cyclic ketones Monocarboxylic acids and derivatives Carboxylic acids Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic homomonocyclic compounds |
| Substituents | Prostaglandin skeleton - Long-chain fatty acid - Fatty alcohol - Hydroxy fatty acid - Ketone - Cyclic ketone - Secondary alcohol - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Hydrocarbon derivative - Alcohol - Organic oxide - Organic oxygen compound - Organooxygen compound - Carbonyl group - Aliphatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as prostaglandins and related compounds. These are unsaturated carboxylic acids consisting of a 20 carbon skeleton that also contains a five member ring, and are based upon the fatty acid arachidonic acid. |
| External Descriptors | Prostaglandins |
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| IUPAC Name | 7-[(1R,2S)-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopent-3-en-1-yl]heptanoic acid |
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| INCHI | InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12-18,21H,2-11H2,1H3,(H,23,24)/b14-12+/t16-,17-,18+/m0/s1 |
| InChIKey | BGKHCLZFGPIKKU-LDDQNKHRSA-N |
| Smiles | CCCCCC(C=CC1C=CC(=O)C1CCCCCCC(=O)O)O |
| Isomeric SMILES | CCCCC[C@@H](/C=C/[C@H]1C=CC(=O)[C@@H]1CCCCCCC(=O)O)O |
| WGK Germany | 3 |
| RTECS | GY5977900 |
| Molecular Weight | 336.47 |
| Reaxy-Rn | 38829333 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38829333&ln= |
| Solubility | Soluble in DMSO to 75 mM and ethanol to 75 mM |
|---|---|
| Molecular Weight | 336.500 g/mol |
| XLogP3 | 4.400 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 13 |
| Exact Mass | 336.23 Da |
| Monoisotopic Mass | 336.23 Da |
| Topological Polar Surface Area | 74.600 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 439.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |