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polymyxin B, Allosteric modulator of P2X7, CAS No.rp174796, Allosteric modulator of P2X7

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rp174796
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rp174796-500μg
500μg
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$1,334.90
rp174796-1mg
1mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$2,334.90
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P2X7 Allosteric modulator (8)

Basic Description

Product Name polymyxin B, Allosteric modulator of P2X7, CAS No.rp174796
Synonyms DivK1c_000732 | Spectrum5_001331 | GTPL10338 | NCGC00178768-01 | Spectrum_001117 | IDI1_000732 | SBI-0051486.P003 | Aerosporin | KBio2_006733 | KBio3_001697 | Spectrum4_000481 | AB00053527_02 | SPBio_000359 | KBioGR_000961 | SCHEMBL7799155 | Spectrum3_000
Grade Moligand™
Specifications & Purity Moligand™
Action Type ALLOSTERIC MODULATOR
Mechanism of action Allosteric modulator of P2X7

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic Polymers
Class Polypeptides
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Polypeptides
Alternative Parents Cyclic peptides  N-acyl-alpha amino acids and derivatives  Macrolactams  Alpha amino acid amides  N-acyl amines  Benzene and substituted derivatives  Secondary carboxylic acid amides  Secondary alcohols  Lactams  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Polypeptide - Cyclic alpha peptide - Macrolactam - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Monocyclic benzene moiety - Fatty amide - N-acyl-amine - Fatty acyl - Benzenoid - Secondary carboxylic acid amide - Secondary alcohol - Amino acid or derivatives - Carboxamide group - Lactam - Organoheterocyclic compound - Azacycle - Carboxylic acid derivative - Organic nitrogen compound - Organic oxide - Organopnictogen compound - Amine - Carbonyl group - Alcohol - Organonitrogen compound - Organooxygen compound - Primary amine - Organic oxygen compound - Hydrocarbon derivative - Primary aliphatic amine - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
External Descriptors Not available

Associated Targets(Human)

P2RX7 Tchem P2X purinoceptor 7 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Storage and Shipping

CAS rp174796

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Genetic information

Alternate Names DivK1c_000732 | Spectrum5_001331 | GTPL10338 | NCGC00178768-01 | Spectrum_001117 | IDI1_000732 | SBI-0051486.P003 | Aerosporin | KBio2_006733 | KBio3_001697 | Spectrum4_000481 | AB00053527_02 | SPBio_000359 | KBioGR_000961 | SCHEMBL7799155 | Spectrum3_000
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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