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Poly-L-Lysine solution - Molecular weight: 150000-300000,0.1 % (w/v) in H2O, high purity , CAS No.25988-63-0

    Grade & Purity:
  • Molecular weight: 150000-300000,0.1 % (w/v) in H2O
In stock
Item Number
P303253
Grouped product items
SKU Size
Availability
Price Qty
P303253-5ml
5ml
10
$37.90
P303253-25ml
25ml
1
$112.90

Basic Description

Synonyms 2olb | DTXSID40948891 | L-Lysine, L-lysyl-L-lysyl- | Lys-Lys-Lys | Y7F82M80K8 | SCHEMBL3796535 | (S)-6-Amino-2-((S)-6-amino-2-((S)-2,6-diaminohexanamido)hexanamido)hexanoic acid | Lysyllysyllysine | lysyl-lysyl-lysine | L-Lysine,L-lysyl-L-lysyl- | (2S)-6-
Specifications & Purity Molecular weight: 150000-300000,0.1 % (w/v) in H2O
Biochemical and Physiological Mechanisms Poly L lysine is a non specific cell adhesion factor that promotes cell adhesion to solid substrates by enhancing the electrostatic interaction between negative ions in the cell membrane and the surface of the culture medium. When adsorbed onto the surfac
Storage Temp Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Description

Poly-L-lysine solution is intended for use as an adhesive subbing solution for immunohistochemistry (IHC) and routine histologic staining preparations. It is tested for use in cell culture applications and is supplied as a sterile-filtered solution

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Amino acids, peptides, and analogues
Intermediate Tree Nodes Peptides
Direct Parent Oligopeptides
Alternative Parents N-acyl-L-alpha-amino acids  Alpha amino acid amides  Medium-chain fatty acids  Amino fatty acids  N-acyl amines  Secondary carboxylic acid amides  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organopnictogen compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aliphatic acyclic compounds
Substituents Alpha-oligopeptide - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - N-acyl-l-alpha-amino acid - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Medium-chain fatty acid - Amino fatty acid - Fatty amide - N-acyl-amine - Fatty acyl - Fatty acid - Secondary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organopnictogen compound - Primary aliphatic amine - Organic nitrogen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organonitrogen compound - Amine - Primary amine - Organooxygen compound - Organic oxygen compound - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as oligopeptides. These are organic compounds containing a sequence of between three and ten alpha-amino acids joined by peptide bonds.
External Descriptors Not available

Names and Identifiers

Pubchem Sid 488184689
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488184689
IUPAC Name (2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]hexanoyl]amino]hexanoic acid
INCHI InChI=1S/C18H38N6O4/c19-10-4-1-7-13(22)16(25)23-14(8-2-5-11-20)17(26)24-15(18(27)28)9-3-6-12-21/h13-15H,1-12,19-22H2,(H,23,25)(H,24,26)(H,27,28)/t13-,14-,15-/m0/s1
InChIKey WBSCNDJQPKSPII-KKUMJFAQSA-N
Smiles C(CCN)CC(C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)N
Isomeric SMILES C(CCN)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)N
PubChem CID 72363

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

14 results found

Lot Number Certificate Type Date Item
C2517507 Certificate of Analysis Dec 13, 2024 P303253
C2517508 Certificate of Analysis Dec 13, 2024 P303253
G2426387 Certificate of Analysis Jun 04, 2024 P303253
G2426394 Certificate of Analysis Jun 04, 2024 P303253
C2401466 Certificate of Analysis Jan 31, 2024 P303253
C2401467 Certificate of Analysis Jan 31, 2024 P303253
C2401468 Certificate of Analysis Jan 31, 2024 P303253
C2401469 Certificate of Analysis Jan 31, 2024 P303253
H2316198 Certificate of Analysis Aug 02, 2023 P303253
H2316199 Certificate of Analysis Aug 02, 2023 P303253
D23231356 Certificate of Analysis Apr 03, 2023 P303253
D2323186 Certificate of Analysis Apr 03, 2023 P303253
D23231344 Certificate of Analysis Apr 03, 2023 P303253
D2323190 Certificate of Analysis Apr 03, 2023 P303253

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Chemical and Physical Properties

Molecular Weight 402.500 g/mol
XLogP3 -5.600
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 8
Rotatable Bond Count 17
Exact Mass 402.295 Da
Monoisotopic Mass 402.295 Da
Topological Polar Surface Area 200.000 Ų
Heavy Atom Count 28
Formal Charge 0
Complexity 463.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Dongchao Qiu, Chuchu Zheng, Youyun Zeng, Lixia Wu, Chen Huang, Ying Ran, Yiqin Ding, Jiayi Shi, Xiaojun Cai, Yihuai Pan.  (2023)  Enzymolysis and photothermal-mediated synergistic antimicrobial nanoplatform with programmed EPS degradation and biofilm penetration capabilities for eradication of biofilm wound infections.  CHEMICAL ENGINEERING JOURNAL,  477  (147217). 
2. Shuo Xu, Jun You, Shaorong Yan, Luting Zhu, Xiaochen Wu.  (2023)  Etamsylate loaded oxidized Konjac glucomannan-ε-polylysine injectable hydrogels for rapid hemostasis and wound healing.  Journal of Materials Chemistry B,     
3. Hao Wang, Zilei Chen, Chao Zhu, Hongxia Du, Jiangsheng Mao, Hongwei Qin, Yongxin She, Mengmeng Yan.  (2023)  An interference-free SERS-based aptasensor for chlorpyrifos detection.  ANALYTICA CHIMICA ACTA,  1268  (341398). 
4. Ruicheng Xu, Jing Tang, Roja Hadianamrei, Suyu Liu, Songwei Lv, Rongrong You, Fang Pan, Peng Zhang, Nan Wang, Zhiqiang Cai, Xiubo Zhao.  (2023)  Antifungal activity of designed α-helical antimicrobial peptides.  Biomaterials Science,  11  (8): (2845-2859). 
5. Wei Zhu, Jing-Yi Tang, Dong Yu, Ai-Guo Shen.  (2023)  Silent Raman imaging of highly effective anti-bacterial activity synchronous with biofilm breakage using poly(4-cyanostyrene)@silver@polylysine nanocomposites.  ANALYST,  148  (3): (628-635). 
6. Lina Wang, Duo Yi, Youfu Geng, Tingting Duan, Zhifeng Tong, Shaolan Chen, Zhiyao Ning, Yu Du, Xueming Hong, Xuejin Li.  (2023)  Ultrasensitive deafness gene DNA hybridization detection employing a fiber optic Mach-Zehnder interferometer: Enabled by a black phosphorus nanointerface.  BIOSENSORS & BIOELECTRONICS,  222  (114952). 
7. Poyu Chen, Chuangwei Zhang, Ping He, Shengyuan Pan, Wenjie Zhong, Yue Wang, Qingyue Xiao, Xinyan Wang, Wenliang Yu, Zhangmin He, Xiang Gao, Jinlin Song.  (2022)  A Biomimetic Smart Nanoplatform as "Inflammation Scavenger" for Regenerative Therapy of Periodontal Tissue.  International Journal of Nanomedicine,  17  (5165-5186). 
8. Wenjie Zhong, Xinyan Wang, Lanxin Yang, Yue Wang, Qingyue Xiao, Simin Yu, Richard D. Cannon, Yan Bai, Chuangwei Zhang, Duanjing Chen, Ping Ji, Xiang Gao, Jinlin Song.  (2022)  Nanocarrier-Assisted Delivery of Metformin Boosts Remodeling of Diabetic Periodontal Tissue via Cellular Exocytosis-Mediated Regulation of Endoplasmic Reticulum Homeostasis.  ACS Nano,  16  (11): (19096–19113). 
9. Anning Li, Siqi Wang, Zhiqiang Zhang, Na Xu, Guixia Ling, Peng Zhang.  (2022)  Poly-l-lysine derivative-coated black phosphorus as a nanoplatform for photothermal chemotherapy to enhance anti-tumor efficiency.  Journal of Materials Chemistry B,  10  (27): (5191-5202). 
10. Yang Hu, Mingxuan Liu, Daquan Zhou, Feng Chen, Qiang Cai, Xiongwei Yan, Jingfeng Li.  (2022)  Gelatine methacrylamide-based multifunctional bilayer hydrogels for accelerating diabetic wound repair.  MATERIALS & DESIGN,  218  (110687). 
11. Xiaomei Dai, Jifang Ma, Ningning Chen, Yuanyuan Cai, Yanping He, Xiangzi Li, Feng Gao.  (2021)  MSNs-Based Nanocomposite for Biofilm Imaging and NIR-Activated Chem/Photothermal/Photodynamic Combination Therapy.  ACS Applied Bio Materials,  (3): (2810–2820). 
12. Ya-Min Shen, Meng-Yue Gao, Xu Chen, Ai-Guo Shen, Ji-Ming Hu.  (2021)  Fine synthesis of Prussian-blue analogue coated gold nanoparticles (Au@PBA NPs) for sorting specific cancer cell subtypes.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  252  (119566). 
13. Meng-Yue Gao, Qiao Chen, Wei Li, Ai-Guo Shen, Ji-Ming Hu.  (2019)  Combined Surface-Enhanced Raman Scattering Emissions for High-Throughput Optical Labels on Micrometer-Scale Objects.  ANALYTICAL CHEMISTRY,  91  (21): (13866–13873). 
14. Chenyue Zhan, Yong Huang, Guifang Lin, Shuailing Huang, Fang Zeng, Shuizhu Wu.  (2019)  A Gold Nanocage/Cluster Hybrid Structure for Whole-Body Multispectral Optoacoustic Tomography Imaging, EGFR Inhibitor Delivery, and Photothermal Therapy.  Small,  15  (33): (1900309). 
15. Jia-Hong Wu, Fang-Qi Shao, Shi-Yi Han, Song Bai, Jiu-Ju Feng, Zhengquan Li, Ai-Jun Wang.  (2019)  Shape-controlled synthesis of well-dispersed platinum nanocubes supported on graphitic carbon nitride as advanced visible-light-driven catalyst for efficient photoreduction of hexavalent chromium.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  535  (41). 
16. Liuyang Xuan, Ming Shi, Shuangshuang Ma, Feng Ye, Xuetao Shi, Ling Yan, Yan Li.  (2018)  Development of Electrospun Composite Fibers in Multiscale Structure and Investigating the Performance on Proliferation and Osteogenic Differentiation of ADSCs.  MACROMOLECULAR MATERIALS AND ENGINEERING,  303  (7): (1800130). 
17. Xueming Bao, Biaobiao Yan, Yuanyuan Yu, Bo Xu, Li Cui, Man Zhou, Qiang Wang, Ping Wang.  (2024)  A facile cellulose finishing strategy through in-situ growth of sliver-doped manganese dioxide assisted by amine-quinone for improving indoor living quality.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  267  (131448). 
18. Jin Bao, Wenping Zeng, Yun Huang, Zhongwei Zhao, Jiajun He, Zhanpeng Du, Fengliang Wang, Huihui Li, Heguo Zeng, Xing Li, Mingshan Wang, Yuanhua Lin, Bingshu Guo, Bo Yu, Haijun Cao.  (2025)  Advancing aqueous zinc-ion battery performance with pullulan through preferential adsorption on zinc anode surfaces and enhanced zinc ion desolvation.  Materials Today Energy,  48  (101790). 
19. Yinghao Li, Dongling Xiao, Weixi Yan, Meilin Jiang, Ju Tan, Zhongliang Qin, Jingting Zhou, Yue Sun, Mingcan Yang, Guanyuan Yang, Yawei Gu, Yong Liu, Chuhong Zhu.  (2025)  Bioinspired hierarchical porous tough adhesive to promote sealing of high-pressure bleeding.  Bioactive Materials,  45  (88). 
20. Gong Can, Lu Xiang-Ting, Zhang Shi-Ding, Xiao Kun, Xu Xu.  (2024)  Detection of lard adulteration in 3 kinds of vegetable oils by liquid chromatography–mass spectrometry with porous graphite carbon column.  ANALYTICAL SCIENCES,  40  (7): (1289-1299). 
21. You Xiaoxiao, Wang Zhongke, Wang Li, Liu Youbo, Chen Hongmei, Lan Xiaorong, Guo Ling.  (2024)  Graphene oxide/ε-poly-L-lysine self-assembled functionalized coatings improve the biocompatibility and antibacterial properties of titanium implants.  Frontiers in Bioengineering and Biotechnology,  12   
22. Peng He, Guanghui Gu, Youyin Xu, Gang Wei, Mingjin Xu.  (2025)  Injectable and self-healing dual-network chitosan/hyaluronic acid/polypeptide (CHP) antibacterial hydrogels for wound healing.  POLYMER,    (128064). 
23. Fu Siyuan, Wang Zhiyu, Huang Peihong, Li Guanjun, Niu Jian, Li Zhiyang, Zu Guangyue, Zhou Pengcheng, Wang Lianhui, Leong David Tai, Ding Xianguang.  (2025)  Programmable production of bioactive extracellular vesicles in vivo to treat myocardial infarction.  Nature Communications,  16  (1): (1-16). 
24. Yingjun Yang, Kuankuan Han, Siyuan Huang, Kai Wang, Yuchen Wang, Shukai Ding, Le Zhang, Miao Zhang, Bingshe Xu, Shufang Ma, Yongtao Wang, Shengli Wu, Xinlong Wang.  (2024)  Revelation of Adhesive Proteins Affecting Cellular Contractility through A Reference-free Traction Force Microscopy.  Journal of Materials Chemistry B,     
25. Yujie Zhang, Xiaojiang Zhang, Lianxi Lv, Sheng Gao, Xiang Li, Ruochen Wang, Pengqian Wang, Feiyu Shi, Junjun She, Ya Wang.  (2025)  Versatile inulin/trans-ferulic acid/silk sericin nanoparticles-nourished probiotic complex with prolonged intestinal retention for synergistic therapy of inflammatory bowel disease.  CARBOHYDRATE POLYMERS,  350  (123063). 

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