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Poly(L-lactide) - average Mₙ 10,000, PDI ≤1.1, high purity , CAS No.33135-50-1
Basic Description
Synonyms
PLA | PLLA
Specifications & Purity
average Mₙ 10,000, PDI ≤1.1
Storage Temp
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
Poly (L-lactide) is a semi-crystalline polymer which exhibits strong optical rotation and good mechanical properties. It is mostly used in the synthesis of degradable polymers which are used in orthopaedic devices, in dental applications, as scaffolds for autografted new skin, wound covers, anastomose systems and stents. They are biodegradable since the polyester backbone degrades by simple hydrolysis to form non-toxic compounds.Drug Delivery including coating nanoparticles; end-group functionalization; macroinitiator or block precursor.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organoheterocyclic compounds
Class
Dioxanes
Subclass
1,4-dioxanes
Intermediate Tree Nodes
Not available
Direct Parent
1,4-dioxanes
Alternative Parents
Dicarboxylic acids and derivatives Lactones Carboxylic acid esters Oxacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework
Aliphatic heteromonocyclic compounds
Substituents
Dicarboxylic acid or derivatives - Para-dioxane - Lactone - Carboxylic acid ester - Oxacycle - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound
Description
This compound belongs to the class of organic compounds known as 1,4-dioxanes. These are organic compounds containing 1,4-dioxane, an aliphatic six-member ring with two oxygen atoms in ring positions 1 and 4.
External Descriptors
a small molecule
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Names and Identifiers
IUPAC Name
3,6-dimethyl-1,4-dioxane-2,5-dione
INCHI
InChI=1S/C6H8O4/c1-3-5(7)10-4(2)6(8)9-3/h3-4H,1-2H3
InChIKey
JJTUDXZGHPGLLC-UHFFFAOYSA-N
Smiles
CC1C(=O)OC(C(=O)O1)C
Isomeric SMILES
CC1C(=O)OC(C(=O)O1)C
Alternate CAS
26161-42-2
Reaxy-Rn
82121
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=82121&ln=
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Sensitivity
Moisture sensitive；Heat sensitive
Melt Point(°C)
180 °C
Molecular Weight
144.120 g/mol
XLogP3
0.600
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
0
Exact Mass
144.042 Da
Monoisotopic Mass
144.042 Da
Topological Polar Surface Area
52.600 Ų
Heavy Atom Count
10
Formal Charge
0
Complexity
155.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
2
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Citations of This Product
1.
Ming Qian, Shun Li, Kun Xi, Jincheng Tang, Xiaofeng Shen, Yong Liu, Ran Guo, Nannan Zhang, Yong Gu, Yun Xu, Wenguo Cui, Liang Chen.
(2023)
ECM-engineered electrospun fibers with an immune cascade effect for inhibiting tissue fibrosis. Acta Biomaterialia,
2.
Zexin Zhao, Yuan Xu, Pengpeng Zou, Long Xu, Jun Cai.
(2023)
Developing a pachyman/polyvinyl alcohol-polylactic acid bilayer film as multifunctional packaging and its application in cherry tomato preservation. LWT-FOOD SCIENCE AND TECHNOLOGY,
186
(115249).
3.
Yang Sun, Qianrong Zhou, Yawei Du, Jian Sun, Wei Bi, Wenjuan Liu, Ruixue Li, Xingwen Wu, Fei Yang, Liang Song, Ni Li, Wenguo Cui, Youcheng Yu.
(2022)
Dual Biosignal-Functional Injectable Microspheres for Remodeling Osteogenic Microenvironment. Small,
18
(36):
(2201656).
4.
Chaojun Fu, Fanrong Ai, Jianzhen Huang, Zhiying Shi, Xiluan Yan, Xiangjuan Zheng.
(2022)
Eu doped Ti3C2 quantum dots to form a ratiometric fluorescence platform for visual and quantitative point-of-care testing of tetracycline derivatives. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,
272
(120956).
5.
Xiumei Yan, Yi Yu, Shaobing Wang, Haixing Xu, Qundi He, Jing Wen, Jingyi Xu, Kebi Li, Zhijun Huang, Peihu Xu.
(2021)
Preparation and characterization of conductive nerve guide conduit filled with dual drug-loaded nanofibers. JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS,
6.
Chenyang Cai, Yongqin Wang, Zechang Wei, Yu Fu.
(2021)
Biomimetic 3D Membranes with MXene Heterostructures for Superior Solar Steam Generation, Water Treatment, and Electricity Generation. Solar RRL,
5
(11):
(2100593).
7.
Xu Haixing, Li Rui, Li Yiping, He Qundi, Yan Xiumei, Shu Tao, Yang Haixia, Lü Yifei, Li Zheng, Xu Runtian, Xiong Chengjie, Xu Peihu.
(2020)
Preparation and Characterization of Poly Lactic Acid/Graphene Oxide/Nerve Growth Factor Scaffold with Electrical Stimulation for Peripheral Nerve Regeneration in vitro. JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION,
35
(6):
(1149-1161).
8.
Xiaonan Deng, Sihong Ye, Kun Liu, Changfeng Li, Fangzhi Liu, Xiaoming Yan.
(2020)
Permeability of N, P, K-fertilizer nutrient and water vapor through PLA, PLA/PS, and PLA/HA membranes. Polish Journal of Chemical Technology,
22
(4):
(61-68).
9.
Hao Zhang, Yilin Dong, Keke Huang, Jingsheng Liu, Bo Dong, Feng Wang.
(2019)
Immortal Ring Opening Polymerization of ε-caprolactone and rac-lactide by magnesium precatalysts bearing sterically congested phenoxide ligands. EUROPEAN POLYMER JOURNAL,
118
(633).
10.
Zhefu Li, Binling Chen, Xianfeng Wang, Jun Nie, Guiping Ma.
(2019)
Electrospun bamboo-like Fe3C encapsulated Fe-Si-N co-doped nanofibers for efficient oxygen reduction. JOURNAL OF COLLOID AND INTERFACE SCIENCE,
546
(231).
11.
Tiantian Song, Weichao Shi.
(2024)
Polymer crystallization and optical birefringence modulated by solvent evaporation in sessile droplets. POLYMER,
307
(127287).
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11 Citations
