Grouped product items
SKU	Size	Availability	Price
Ab175635-100μg	100μg	10	$189.90
Ab175635-1mg	1mg	4	$919.90
Ab175635-5mg	5mg	1	$2,299.90
Ab175635-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,679.90

Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)

View related series

Click to view target information: CD79B

Accession#:P40259 (6) CD79B (6) Gene ID:974 (6) MC-VC-PAB-MMAE (18)

Basic Description

Product Name	Polatuzumab vedotin-piiq (anti-CD79b) - Primary antibody, specific to CD79B, >90% (SDS-PAGE&SEC), high purity, Human IgG1, Antibody of CD79B
Synonyms	AGM6 antibody \| B cell antigen receptor complex associated protein beta chain antibody \| B cell specific glycoprotein B29 antibody \| B-cell antigen receptor complex-associated protein beta chain antibody \| B-cell-specific glycoprotein B29 antibody \| B29 a
Specifications & Purity	Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Host species	Human
Specificity	CD79B
Conjugation	MC-VC-PAB-MMAE
Grade	Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type	ANTIBODY
Mechanism of action	Antibody of CD79B
Product Description	Polatuzumab vedotin-piiq (anti-CD79b) is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. Polatuzumab vedotin-piiq (anti-CD79b) has the potential for the research of Large B-cell lymphomas (LBCL). Purity >90% (SDS-PAGE&SEC) Endotoxin Level < 1.0EU/mg

Product Properties

Isotype	Human IgG1
Light Chain Type	kappa
SDS-PAGE	150.53 kDa
Purification Method	Protein A purified
Purity	>90% (SDS-PAGE&SEC)
Shape	Liquid
Concentration	See COA
Storage Temp	Store at -80°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS	1313206-42-6

Associated Targets(Human)

CD79B Tclin B-cell antigen receptor complex-associated protein beta chain (0 Activities)

Discover Target: CD79B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Images

Flow Cytometry: Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635)

Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD79b with Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).

SEC: Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635)

Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) - SEC
The purity of Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) is more than 95% verified by HPLC.

ELISA: Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635)

Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) - ELISA
Immobilized Recombinant Human CD79B protein (rp144109) at 1.0 μg/mL can bind Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) with the EC50 of 51.95 ng/mL.

Flow Cytometry: Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635)

Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD79b (red) with Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0607172	Certificate of Analysis	Jun 21, 2024	Ab175635
ZJ24F0607171	Certificate of Analysis	Jun 21, 2024	Ab175635
ZJ24F0607170	Certificate of Analysis	Jun 21, 2024	Ab175635

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Polatuzumab vedotin-piiq (anti-CD79b) - Primary antibody, specific to CD79B, >90% (SDS-PAGE&SEC), high purity, Human IgG1, Antibody of CD79B, Antibody of CD79B