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PLX7922 - 10mM in DMSO, high purity , CAS No.1638772-61-8(DMSO)

COA

Grade & Purity:

10mM in DMSO

Cas Number: 1638772-61-8(DMSO)
Molecular Weight: 464.58

In stock

Item Number

P656692

Grouped product items
SKU	Size	Availability	Price	Qty
P656692-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$715.90

View related series

Compound libraries (12325) MAPK/ERK Pathway (546) Raf (69)

Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	PLX7922, a RAF inhibitor, can bind with BRAF V600E . PLX7922 inhibits pERK in BRAF V600E cell lines, and activates pERK in mutant NRAS cell lines.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	PLX7922, a RAF inhibitor, can bind with BRAF V600E . PLX7922 inhibits pERK in BRAF V600E cell lines, and activates pERK in mutant NRAS cell lines In Vitro PLX7922 (1-1000 nM) inhibits pERK in BRAF V600E cell lines, activates pERK in mutant NRAS cell lines (B9 and IPC-298). MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:RAF

Names and Identifiers

Smiles	CCN(C)S(=O)(=O)NC1=CC=CC(=C1F)C2=C(SC(=N2)C(C)(C)C)C3=NC(=NC=C3)N
Molecular Weight	464.58

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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