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PF 750 - ≥98%(HPLC), high purity , CAS No.959151-50-9, Inhibitor of epoxide hydrolase 2;Inhibitor of Fatty acid amide hydrolase

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PF 750 - ≥98%(HPLC), high purity , CAS No.959151-50-9, Inhibitor of epoxide hydrolase 2;Inhibitor of Fatty acid amide hydrolase

COA

Grade & Purity:

Moligand™

≥98%(HPLC)

Cas Number: 959151-50-9
Molecular Weight: 345.44
PubChem CID: 25154868

In stock

Item Number

P288561

Grouped product items
SKU	Size	Availability	Price
P288561-5mg	5mg	3	$88.90
P288561-10mg	10mg	3	$137.90
P288561-25mg	25mg	3	$296.90
P288561-50mg	50mg	2	$474.90
P288561-100mg	100mg	2	$855.90

Selective FAAH inhibitor

View related series

Autophagy (1917) epoxide hydrolase 2 Inhibitor (11) FAAH (34) Fatty acid amide hydrolase Inhibitor (21) Lipid metabolism (1912) Metabolic Enzyme/Protease (4860) Neuronal Signaling (3320)

Basic Description

Synonyms	NCGC00370873-01 \| Q27088336 \| N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide \| BDBM26740 \| BRD-K83213911-001-01-0 \| DTXSID00648906 \| PF750 \| PF-750 \| N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide \| PF 750 \| GTPL5244 \| PF-750, >=98% (HP
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	Irreversible fatty acid amide hydrolase (FAAH) inhibitor (IC50= 16.2 nM) that displays no activity at a range of other serine hydrolases. Selectively inhibits FAAH within the central nervous system. Orally active.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of epoxide hydrolase 2;Inhibitor of Fatty acid amide hydrolase
Product Description	Product Describtion: PF 750 is a selective and covalent fatty acid amide hydrolase inhibitor, It shows IC50s varied from 16.2-595 nM in different pre-incubation times.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Quinolines and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Quinolines and derivatives
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Quinolines and derivatives
Alternative Parents	N-phenylureas Piperidinecarboxamides Pyridines and derivatives Heteroaromatic compounds Ureas Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	N-phenylurea - Quinoline - 1-piperidinecarboxamide - Piperidinecarboxamide - Monocyclic benzene moiety - Piperidine - Pyridine - Benzenoid - Heteroaromatic compound - Carbonic acid derivative - Urea - Azacycle - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as quinolines and derivatives. These are compounds containing a quinoline moiety, which consists of a benzene ring fused to a pyrimidine ring to form benzo[b]azabenzene.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

EPHX2 Tchem Bifunctional epoxide hydrolase 2 (2 Activities)

Discover Target: EPHX2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FAAH Tchem Fatty-acid amide hydrolase 1 (7 Activities)

Discover Target: FAAH

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
INCHI	InChI=1S/C22H23N3O/c26-22(24-20-7-2-1-3-8-20)25-12-10-17(11-13-25)14-18-15-19-6-4-5-9-21(19)23-16-18/h1-9,15-17H,10-14H2,(H,24,26)
InChIKey	BIODYGOZWZNCAG-UHFFFAOYSA-N
Smiles	C1CN(CCC1CC2=CC3=CC=CC=C3N=C2)C(=O)NC4=CC=CC=C4
Isomeric SMILES	C1CN(CCC1CC2=CC3=CC=CC=C3N=C2)C(=O)NC4=CC=CC=C4
WGK Germany	3
PubChem CID	25154868
Molecular Weight	345.44

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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6 results found

Lot Number	Certificate Type	Date	Item
I2205104	Certificate of Analysis	Jun 10, 2025	P288561
I2205105	Certificate of Analysis	Jun 10, 2025	P288561
I2205106	Certificate of Analysis	Jun 10, 2025	P288561
I2205107	Certificate of Analysis	Jun 10, 2025	P288561
I2205172	Certificate of Analysis	Jun 10, 2025	P288561
L2418203	Certificate of Analysis	Jun 27, 2022	P288561

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 34.54, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 34.54, Max Conc. mM: 100
Molecular Weight	345.400 g/mol
XLogP3	4.100
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	345.184 Da
Monoisotopic Mass	345.184 Da
Topological Polar Surface Area	45.200 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	454.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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