Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176657-100μg
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100μg |
10
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$129.90
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Ab176657-1mg
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1mg |
4
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$649.90
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Ab176657-5mg
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5mg |
1
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$1,699.90
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Ab176657-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$2,799.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | PF-03732010 (anti-CDH3) - Primary antibody, specific to CDH3, >95%, high purity, Human IgG1, INHIBITOR of Cadherin-3 inhibitor |
|---|---|
| Synonyms | CADH3_HUMAN antibody | Cadherin 3 antibody | Cadherin 3 precursor antibody | Cadherin 3 type 1 antibody | Cadherin-3 antibody | Cadp antibody | Calcium dependent adhesion protein placental antibody | CDH 3 antibody | CDH3 antibody | CDH3 protein antibody |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CDH3 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Cadherin-3 inhibitor |
| Product Description |
PF-03732010 (anti-CDH3) is a antibody targeting p-cadherin. It binds to and inhibits the activity of p-cadherin which may inhibit tumor cell invasion and proliferation in p-cadherin expressing tumor cells. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | lambda |
| SDS-PAGE | 28.2 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 202.8 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
PF-03732010 (anti-CDH3) (Ab176657) - Flow
Human CDH3 HEK293 cells were stained with PF-03732010 (anti-CDH3) (Ab176657) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC₅₀=140 nM.
PF-03732010 (anti-CDH3) (Ab176657) - SEC
The purity of PF-03732010 (anti-CDH3) (Ab176657) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 18, 2024 | Ab176657 | |
| Certificate of Analysis | Jun 18, 2024 | Ab176657 | |
| Certificate of Analysis | Jun 18, 2024 | Ab176657 |