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Pergolide - >97.0%(HPLC), high purity , Dopamine receptor agonist, CAS No.66104-22-1, Dopamine receptor agonist

1 Citations COA COA
In stock
Item Number
P160441
Grouped product items
SKU Size
Availability
 Price Qty
P160441-10mg
10mg
3
$26.90
P160441-50mg
50mg
2
$103.90
P160441-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$186.90
P160441-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$419.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet
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Basic Description

Synonyms BPBio1_000254 | 9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide) | KBio2_002127 | BRD-K60770992-066-15-1 | D08339 | KBioGR_001409 | (8beta)-8-[(methylthio)methyl]-6-propylergoline | P2200 | BIDD:GT0177 | PER
Specifications & Purity Moligand™, ≥97%(HPLC)
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Action Type AGONIST
Mechanism of action Dopamine receptor agonist
Product Description

Product Description：

Pergolide is an ergoline-based dopamine receptor agonist.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Quinolines and derivatives
Subclass Indoloquinolines
Intermediate Tree Nodes Not available
Direct Parent Indoloquinolines
Alternative Parents Ergoline and derivatives  Benzoquinolines  Pyrroloquinolines  3-alkylindoles  Isoindoles and derivatives  Aralkylamines  Benzenoids  Piperidines  Pyrroles  Heteroaromatic compounds  Trialkylamines  Dialkylthioethers  Azacyclic compounds  Sulfenyl compounds  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Ergoline skeleton - Indoloquinoline - Benzoquinoline - Pyrroloquinoline - 3-alkylindole - Indole - Indole or derivatives - Alkaloid or derivatives - Isoindole or derivatives - Aralkylamine - Benzenoid - Piperidine - Heteroaromatic compound - Pyrrole - Tertiary aliphatic amine - Tertiary amine - Sulfenyl compound - Dialkylthioether - Azacycle - Thioether - Amine - Organosulfur compound - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as indoloquinolines. These are polycyclic aromatic compounds containing an indole fused to a quinoline.
External Descriptors organic heterotetracyclic compound - methyl sulfide - diamine

Product Properties

ALogP 4.2

Associated Targets(Human)

CYP2D6 Tclin Cytochrome P450 2D6 (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
DRD1 Tclin D(1A) dopamine receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
DRD2 Tclin D(2) dopamine receptor (7 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
DRD4 Tchem D(4) dopamine receptor (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
DRD3 Tclin D(3) dopamine receptor (5 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
DRD5 Tchem D(1B) dopamine receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
HTR1B Tclin 5-hydroxytryptamine receptor 1B (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ADRA2B Tclin Alpha-2B adrenergic receptor (3 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ADRA2C Tclin Alpha-2C adrenergic receptor (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
HTR2A Tclin 5-hydroxytryptamine receptor 2A (5 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
HTR7 Tclin 5-hydroxytryptamine receptor 7 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ADRA2A Tclin Alpha-2A adrenergic receptor (2 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
HTR1D Tclin 5-hydroxytryptamine receptor 1D (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
HTR2C Tclin 5-hydroxytryptamine receptor 2C (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
HTR1A Tclin 5-hydroxytryptamine receptor 1A (3 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
HTR6 Tchem 5-hydroxytryptamine receptor 6 (3 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
HTR2B Tclin 5-hydroxytryptamine receptor 2B (3 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid 504753648
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504753648
IUPAC Name (6aR,9R,10aR)-9-(methylsulfanylmethyl)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline
INCHI InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1
InChIKey YEHCICAEULNIGD-MZMPZRCHSA-N
Smiles CCCN1CC(CC2C1CC3=CNC4=CC=CC2=C34)CSC
Isomeric SMILES CCCN1C[C@@H](C[C@H]2[C@H]1CC3=CNC4=CC=CC2=C34)CSC
RTECS KE6344964
PubChem CID 47811
Molecular Weight 314.49
Reaxy-Rn 5091461

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Sensitivity Heat sensitive
Melt Point(°C) 210℃
Molecular Weight 314.500 g/mol
XLogP3 4.200
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 4
Exact Mass 314.182 Da
Monoisotopic Mass 314.182 Da
Topological Polar Surface Area 44.300 Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 388.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Mengwen Shi, Jiaxin Tang, Chengmei Yang, Guanlong Guo, Huaxing Ou, Weihai Chen.  (2021)  Pimavanserin, a 5-hydroxytryptamine 2A receptor inverse agonist, reverses prepulse inhibition deficits in the nucleus accumbens and ventral hippocampus.  NEUROPHARMACOLOGY,  201  (108838). 

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