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PDK1-IN-RS2 - 98%, high purity , CAS No.1643958-89-7

COA

Grade & Purity:

≥98%

Cas Number: 1643958-89-7
Molecular Weight: 380.89

In stock

Item Number

P646789

Grouped product items
SKU	Size	Availability	Price
P646789-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90
P646789-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$250.90
P646789-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$550.90
P646789-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$850.90
P646789-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,350.90

View related series

PDK-1 (15) PI3K/Akt/mTOR (765)

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	PDK1-IN-RS2 is a mimic of peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor with a K d of 9 μM. PDK1-IN-RS2 suppresses the activation of the downstream kinases S6K1 by PDK1.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	PDK1-IN-RS2 is a mimic of peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor with a K d of 9 μM. PDK1-IN-RS2 suppresses the activation of the downstream kinases S6K1 by PDK1 In Vitro PDK1-IN-RS2 stimulates the catalytic activity of PDK1 toward a peptide substrate by sixfold. The sulfonyl group of PDK1-IN-RS2 interacts with Arg131 through a salt bridge, because the sulfonamide is likely ionized under the crystallization conditions. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Kd: 9 μM (PDK1)

Names and Identifiers

Smiles	O=S(C1=CC2=CC=CC=C2S1)(NC3=NC4=CC=C(C=C4S3)Cl)=O
Molecular Weight	380.89

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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