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PD-1-IN-24 - 10mM in DMSO, high purity , CAS No.2360909-50-6(DMSO)

COA

Grade & Purity:

10mM in DMSO

Cas Number: 2360909-50-6(DMSO)
Molecular Weight: 469.50

In stock

Item Number

P654665

Grouped product items
SKU	Size	Availability	Price	Qty
P654665-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$465.90

View related series

Compound libraries (12325) Immunology/Inflammation (1929) PD-1/PD-L1 (59)

Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor.
Storage Temp	Protected from light,Desiccated,Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	PD-1-IN-24 (compound 1) is an orally active PD-1 inhibitor. In Vivo PD-1-IN-24 (compound 1, 15mg/kg, PO, BID) exhibits TGI(%) of 19.96% in the subcutaneous 4T1 murine breast cancer model in BALB/c mice . PD-1-IN-24 (compound 1, 15mg/kg, PO, BID) dose-dependently inhibits tumor growth in the Bl6F10 models with TGI% of 35.59% (30 mg/kg), 38.87% (60 mg/kg) and 47.35% (120 mg/kg), respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Names and Identifiers

Smiles	CC1=C(C2=CC=CC=C2)C=CC=C1/C=C/C3=C(C=CC(CN[C@](CO)(C)C(O)=O)=C3)C(F)(F)F
Molecular Weight	469.50

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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