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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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P113572-1mg
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1mg |
2
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$103.90
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P113572-5mg
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5mg |
2
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$378.90
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P113572-10mg
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10mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$754.90
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| Synonyms | 4097-04-5 | Adenosine 5'-(hexahydrogen pentaphosphate), 5'.5'-ester with adenosine, pentasodium salt | EINECS 223-852-7 | P1,P5-Di(adenosine-5') pentaphosphate pentasodium salt | pentasodium;bis[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]metho |
|---|---|
| Specifications & Purity | ≥96% |
| Biochemical and Physiological Mechanisms | Polyphosphate diphosphate is stored in the secretory vesicles of platelets, chromaffin cells and nerve cells. When it is released into extracellular matrix, it will affect many biological activities in many target tissues. In the nervous system, it plays |
| Storage Temp | Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
A diadenosine polyphosphate stored in secretory granules of chromaffin and neuronal cells and thrombocytes. After release into the extracellular space, the compound affects a variety of biological activities in a wide range of target tissues. In the nervous system it acts through various purinergic receptors. It also activates 5'-nucleotidase and inhibits adenosine kinase activity in vitro. Ap5A is metabolized by soluble enzymes in the blood plasma and by membrane-bound ectoenzymes of a number of cell types including endothelial and smooth muscle cells. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Nucleosides, nucleotides, and analogues |
| Class | (5'->5')-dinucleotides |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | (5'->5')-dinucleotides |
| Alternative Parents | Purine ribonucleoside polyphosphates Purine nucleotide sugars Purine ribonucleoside monophosphates Pentose phosphates Glycosylamines 6-aminopurines Monosaccharide phosphates Aminopyrimidines and derivatives Alkyl phosphates N-substituted imidazoles Imidolactams Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Hydrocarbon derivatives Organic oxides Organic sodium salts Organic zwitterions Organopnictogen compounds Primary amines |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | (5'->5')-dinucleotide - Purine ribonucleoside polyphosphate - Purine nucleotide sugar - Purine ribonucleoside monophosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Monosaccharide phosphate - Imidazopyrimidine - Purine - Aminopyrimidine - Imidolactam - Monosaccharide - Alkyl phosphate - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Azole - Imidazole - Tetrahydrofuran - Heteroaromatic compound - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Organic alkali metal salt - Azacycle - Organic oxide - Amine - Organonitrogen compound - Organic zwitterion - Alcohol - Organic salt - Organic sodium salt - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Primary amine - Hydrocarbon derivative - Organopnictogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage. |
| External Descriptors | Not available |
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| IUPAC Name | pentasodium;bis[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate |
|---|---|
| INCHI | InChI=1S/C20H29N10O22P5.5Na/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(47-19)1-45-53(35,36)49-55(39,40)51-57(43,44)52-56(41,42)50-54(37,38)46-2-8-12(32)14(34)20(48-8)30-6-28-10-16(22)24-4-26-18(10)30;;;;;/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H,41,42)(H,43,44)(H2,21,23,25)(H2,22,24,26);;;;;/q;5*+1/p-5/t7-,8-,11-,12-,13-,14-,19-,20-;;;;;/m1...../s1 |
| InChIKey | NNMFUJJMJIYTSP-CSMIRWGRSA-I |
| Smiles | C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)N.[Na+].[Na+].[Na+].[Na+].[Na+] |
| Isomeric SMILES | C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OC[C@@H]4[C@H]([C@H]([C@@H](O4)N5C=NC6=C(N=CN=C65)N)O)O)O)O)N.[Na+].[Na+].[Na+].[Na+].[Na+] |
| WGK Germany | 3 |
| Alternate CAS | 41708-91-2 |
| PubChem CID | 16219241 |
| Molecular Weight | 1026.28 |
| Beilstein | 4949216 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 04, 2025 | P113572 | |
| Certificate of Analysis | May 05, 2023 | P113572 | |
| Certificate of Analysis | May 05, 2023 | P113572 | |
| Certificate of Analysis | Jan 04, 2023 | P113572 | |
| Certificate of Analysis | Jan 04, 2023 | P113572 | |
| Certificate of Analysis | Jan 04, 2023 | P113572 | |
| Certificate of Analysis | Jan 04, 2023 | P113572 | |
| Certificate of Analysis | Jan 04, 2023 | P113572 | |
| Certificate of Analysis | Jul 30, 2022 | P113572 | |
| Certificate of Analysis | Jul 30, 2022 | P113572 | |
| Certificate of Analysis | Jul 30, 2022 | P113572 |
| Solubility | Soluble in water (50 mg/ml.clear,Slightly yellow |
|---|---|
| Molecular Weight | 1026.300 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 30 |
| Rotatable Bond Count | 16 |
| Exact Mass | 1025.92 Da |
| Monoisotopic Mass | 1025.92 Da |
| Topological Polar Surface Area | 495.000 Ų |
| Heavy Atom Count | 62 |
| Formal Charge | 0 |
| Complexity | 1540.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 8 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 6 |