Basic Description

Synonyms	p-Aminophenylmercuric Acetate - CAS 6283-24-5 - Calbiochem \| Mercury, (acetato-O)(4-aminophenyl)- \| Mercury, (acetato-.kappa.O)(4-aminophenyl)- \| acetoxymercurianiline \| FT-0617597 \| 4-Aminophenylmercury acetate \| 1,3-Bis(2,4-diaminophenoxy)propane 4HCl,
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP) . P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Product Description	p-Aminophenylmercuric acetate is an organomercurial activator of matrix metalloproteinases (MMP). P-Aminophenylmercuric acetate participates in the activation and inhibition of MMP-8 by attacking protein sulfhydryl or inducing cysteine switching reaction. p-Aminophenylmercuric acetate promotes the shedding of betacellulin precursor (pro-BTC). p-Aminophenylmercuric acetate influences the binding of agonists and antagonists to the opiate receptor . In Vitro p-Aminophenylmercuric acetate (APMA) (0-30 µM; 20 min) decreases the apparent number of dihydromorphine binding sites and increases the sensitivity of agonist binding to the inhibitory effects of sodium in rat brain homogenate. p-Aminophenylmercuric acetate (0.5 mM; 30 min) activates the MMP-2 and MMP-9. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Aniline and substituted anilines

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Aniline and substituted anilines
Intermediate Tree Nodes	Not available
Direct Parent	Aniline and substituted anilines
Alternative Parents	Metal aryls Aryl mercury compounds Organic transition metal salts Monocarboxylic acids and derivatives Carboxylic acids Primary amines Organic oxides Hydrocarbon derivatives Carbonyl compounds Organic cations
Molecular Framework	Not available
Substituents	Aniline or substituted anilines - Aryl mercury compound - Metal aryl - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Organic transition metal salt - Organic nitrogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Organometallic compound - Organomercurial-compound - Organic transition metal moeity - Carbonyl group - Amine - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organic cation - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as aniline and substituted anilines. These are organic compounds containing an aminobenzene moiety.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	acetyloxy-(4-aminophenyl)mercury
INCHI	InChI=1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1
InChIKey	RXSUFCOOZSGWSW-UHFFFAOYSA-M
Smiles	CC(=O)O[Hg]C1=CC=C(C=C1)N
Isomeric SMILES	CC(=O)O[Hg]C1=CC=C(C=C1)N
Molecular Weight	351.75

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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9 results found

Lot Number	Certificate Type	Date	Item
F2509508	Certificate of Analysis	May 29, 2025	P649286
F2509510	Certificate of Analysis	May 29, 2025	P649286
F2509525	Certificate of Analysis	May 29, 2025	P649286
F2509509	Certificate of Analysis	May 29, 2025	P649286
K2411330	Certificate of Analysis	Nov 05, 2024	P649286
K2411331	Certificate of Analysis	Nov 05, 2024	P649286
K2411332	Certificate of Analysis	Nov 05, 2024	P649286
K2411333	Certificate of Analysis	Nov 05, 2024	P649286
K2411334	Certificate of Analysis	Nov 05, 2024	P649286

Chemical and Physical Properties

Solubility	DMSO : 125 mg/mL (355.37 mM; ultrasonic and warming and heat to 60°C)
Molecular Weight	351.750 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	353.034 Da
Monoisotopic Mass	353.034 Da
Topological Polar Surface Area	52.300 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	155.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Feng Wu, Yu Huang, Xian Yang, Jing-Jing Hu, Xiaoding Lou, Fan Xia, Yanlin Song, Lei Jiang. (2021) Tunning Intermolecular Interaction of Peptide-Conjugated AIEgen in Nano-Confined Space for Quantitative Detection of Tumor Marker Secreted from Cells. ANALYTICAL CHEMISTRY, 93 (48): (16257–16263).
2. Zhu Dan, Zhong Hanyan, Shi Jingzhan, Liu Qiang, Wang Yiping. (2025) Ratiometric surface-enhanced Raman scattering quantification of extracellular matrix metalloproteinase-2 activity for tumor diagnosis. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, (1-11).

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SKU	Size	Availability	Price
P649286-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$36.90
P649286-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$110.90
P649286-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90

p-Aminophenylmercuric acetate - 0.93, high purity , CAS No.6283-24-5