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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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O288636-10mg
|
10mg |
1
|
$194.90
|
|
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O288636-25mg
|
25mg |
1
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$399.90
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|
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O288636-50mg
|
50mg |
1
|
$718.90
|
|
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O288636-100mg
|
100mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,219.90
|
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Potent ROCK inhibitor
| Synonyms | 2-Fluoro-N-[[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methyl]benzenemethanamine dihydrochloride |
|---|---|
| Specifications & Purity | ≥98%(HPLC) |
| Biochemical and Physiological Mechanisms | Potent ROCK inhibitor (IC50= 10 nM). Suppresses pMYPT1 and pCofilin levels in non-small cell lung carcinoma (NSCLC) cell lines. Also inhibits anchorage-independent growth of NSCLC cell linesin vitro. |
| Storage Temp | Room temperature,Desiccated |
| Shipped In | Normal |
| Pubchem Sid | 504772649 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772649 |
| IUPAC Name | N-[(2-fluorophenyl)methyl]-1-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methanamine;dihydrochloride |
| INCHI | InChI=1S/C21H18FN3.2ClH/c22-20-4-2-1-3-17(20)14-23-13-15-5-7-16(8-6-15)18-9-11-24-21-19(18)10-12-25-21;;/h1-12,23H,13-14H2,(H,24,25);2*1H |
| InChIKey | ZRBCUSMZOWMVJS-UHFFFAOYSA-N |
| Smiles | C1=CC=C(C(=C1)CNCC2=CC=C(C=C2)C3=C4C=CNC4=NC=C3)F.Cl.Cl |
| Isomeric SMILES | C1=CC=C(C(=C1)CNCC2=CC=C(C=C2)C3=C4C=CNC4=NC=C3)F.Cl.Cl |
| PubChem CID | 91691120 |
| Molecular Weight | 404.31 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 20, 2024 | O288636 | |
| Certificate of Analysis | Feb 20, 2024 | O288636 | |
| Certificate of Analysis | Feb 20, 2024 | O288636 | |
| Certificate of Analysis | Feb 20, 2024 | O288636 | |
| Certificate of Analysis | Feb 20, 2024 | O288636 | |
| Certificate of Analysis | Feb 20, 2024 | O288636 | |
| Certificate of Analysis | Feb 20, 2024 | O288636 |
| Solubility | Solvent:DMSO, Max Conc. mg/mL: 40.43, Max Conc. mM: 100 |
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