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OARV-771 - 98%, high purity , CAS No.2683008-37-7

COA

Grade & Purity:

≥98%

Cas Number: 2683008-37-7
Molecular Weight: 987.62

In stock

Item Number

O651646

Grouped product items
SKU	Size	Availability	Price	Qty
O651646-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,450.90
O651646-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$850.90

View related series

Aliphatic Linkers (102) DBCO PEG (216) Epigenetic Reader Domain (314) Epigenetics (1496) Hydroxy PEG (472) PROTAC (2077) PROTAC linker (720) PROTACs (183)

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4 , Brd2 and Brd3 , respectively.
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4 , Brd2 and Brd3 , respectively In Vitro OARV-771 shows antiproliferative effect with an EC 50 value of 4 nM in MV4;11. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:BRD4 6 nM (DC 50 ) BRD2 1 nM (DC 50 ) BRD3 4 nM (DC 50 ) VHL

Names and Identifiers

Smiles	CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(OCCOCCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@H](C4)O)C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)=O)=O)=O)C7=NN=C(C)N27
Molecular Weight	987.62

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