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SKU | Taille | Disponibilité |
Prix | Qté |
---|---|---|---|---|
O129631-5mg
|
5mg |
3
|
56,90$US
|
|
O129631-25mg
|
25mg |
3
|
235,90$US
|
|
O129631-100mg
|
100mg |
2
|
783,90$US
|
|
Oct4 activator; enhances iPSC reprogramming efficiency
Synonymes | OAC-1 | Oct4-activating Compound 1 | N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide |
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Spécifications et pureté | ≥97% |
Mécanismes biochimiques et physiologiques | Oct4 activator. Enhances and accelerates iPSC reprogramming in the presence of 4F (Oct4, Sox2, c-Myc and Klf4) by ~20-fold compared to 4F alone. Induces mRNA expression of Oct4, Sox2 and Nanog and also Tet1. Displays no effects on p53-p21 pathway or Wnt-β |
Température de stockage | Store at -20°C |
Expédié en |
Ice chest + Ice pads Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles. |
Product Description |
AC1 (Oct4-activating compound 1) can enhance the efficiency of reprogramming. |
Taxonomy Tree
Kingdom | Organic compounds |
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Superclass | Organoheterocyclic compounds |
Classe | Pyrrolopyridines |
Subclass | Not available |
Intermediate Tree Nodes | Not available |
Direct Parent | Pyrrolopyridines |
Alternative Parents | Benzamides Benzoyl derivatives Pyridines and derivatives Imidolactams Pyrroles Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives |
Molecular Framework | Aromatic heteropolycyclic compounds |
Substituents | Benzamide - Benzoic acid or derivatives - Pyrrolopyridine - Benzoyl - Monocyclic benzene moiety - Pyridine - Benzenoid - Imidolactam - Pyrrole - Heteroaromatic compound - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound |
Description | This compound belongs to the class of organic compounds known as pyrrolopyridines. These are compounds containing a pyrrolopyridine moiety, which consists of a pyrrole ring fused to a pyridine. Pyrrole is 5-membered ring consisting of four carbon atoms and one nitrogen atom. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center. |
External Descriptors | Not available |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | Références |
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IUPAC Name | N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide |
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INCHI | InChI=1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18) |
InChIKey | HWJRIFZDXJKJJN-UHFFFAOYSA-N |
Smiles | C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3 |
Isomères SMILES | C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3 |
WGK Allemagne | 3 |
Poids moléculaire | 237.26 |
Reaxy-Rn | 32136747 |
Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32136747&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Article |
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Certificate of Analysis | Jan 11, 2023 | O129631 |
Solubilité | Solvent:DMSO, Max Conc. mg/mL: 23.73, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 23.73, Max Conc. mM: 100 |
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Sensibilité | Light Sensitive,Air Sensitive,Heat Sensitive |
Indice de réfraction | 1.76 |
Point d'ébullition (°C) | ~386.6 °C at 760 mmHg |
Point de fusion (°C) | 197.05°C |
Poids moléculaire | 237.260 g/mol |
XLogP3 | 2.100 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 2 |
Exact Mass | 237.09 Da |
Monoisotopic Mass | 237.09 Da |
Topological Polar Surface Area | 57.800 Ų |
Heavy Atom Count | 18 |
Formal Charge | 0 |
Complexity | 301.000 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
The total count of all stereochemical bonds | 0 |
Covalently-Bonded Unit Count | 1 |