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OAC1 - ≥97%, high purity , CAS No.300586-90-7

    Grade & Purity:
  • ≥97%
En stock
Item Number
O129631
Articles du produit groupé
SKU Taille
Disponibilité
Prix Qté
O129631-5mg
5mg
3
56,90$US
O129631-25mg
25mg
3
235,90$US
O129631-100mg
100mg
2
783,90$US

Oct4 activator; enhances iPSC reprogramming efficiency

Description générale

Synonymes OAC-1 | Oct4-activating Compound 1 | N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
Spécifications et pureté ≥97%
Mécanismes biochimiques et physiologiques Oct4 activator. Enhances and accelerates iPSC reprogramming in the presence of 4F (Oct4, Sox2, c-Myc and Klf4) by ~20-fold compared to 4F alone. Induces mRNA expression of Oct4, Sox2 and Nanog and also Tet1. Displays no effects on p53-p21 pathway or Wnt-β
Température de stockage Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Product Description

AC1 (Oct4-activating compound 1) can enhance the efficiency of reprogramming.
An Oct-4 activator which increases mRNA expression of Oct-4, Sox-2, Nanog, and Tet1

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Classe Pyrrolopyridines
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Pyrrolopyridines
Alternative Parents Benzamides  Benzoyl derivatives  Pyridines and derivatives  Imidolactams  Pyrroles  Heteroaromatic compounds  Secondary carboxylic acid amides  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Benzamide - Benzoic acid or derivatives - Pyrrolopyridine - Benzoyl - Monocyclic benzene moiety - Pyridine - Benzenoid - Imidolactam - Pyrrole - Heteroaromatic compound - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as pyrrolopyridines. These are compounds containing a pyrrolopyridine moiety, which consists of a pyrrole ring fused to a pyridine. Pyrrole is 5-membered ring consisting of four carbon atoms and one nitrogen atom. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center.
External Descriptors Not available

Cibles associées (non humaines)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mécanismes d'action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name Références

Noms et identifiants

IUPAC Name N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide
INCHI InChI=1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)
InChIKey HWJRIFZDXJKJJN-UHFFFAOYSA-N
Smiles C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3
Isomères SMILES C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3
WGK Allemagne 3
Poids moléculaire 237.26
Reaxy-Rn 32136747
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32136747&ln=

Certificats (CoA, COO, BSE/TSE et tableau d'analyse)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

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Lot Number Certificate Type Date Article
D1928143 Certificate of Analysis Jan 11, 2023 O129631

Propriétés chimiques et physiques

Solubilité Solvent:DMSO, Max Conc. mg/mL: 23.73, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 23.73, Max Conc. mM: 100
Sensibilité Light Sensitive,Air Sensitive,Heat Sensitive
Indice de réfraction 1.76
Point d'ébullition (°C) ~386.6 °C at 760 mmHg
Point de fusion (°C) 197.05°C
Poids moléculaire 237.260 g/mol
XLogP3 2.100
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 2
Exact Mass 237.09 Da
Monoisotopic Mass 237.09 Da
Topological Polar Surface Area 57.800 Ų
Heavy Atom Count 18
Formal Charge 0
Complexity 301.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Calculateurs de solution

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