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ο-Tolidine - analytical standard,for environmental analysis,≥99%(GC), high purity , CAS No.119-93-7

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Item Number
T100412
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T100412-1g
1g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$104.90

Basic Description

Synonyms Fast Dark Blue Base R | I-Tolidine | T0255 | UNII-63HLO2IV6K | AMY40780 | 3,3'-Dimethyl-4,4'-diaminobiphenyl | RCRA waste number U095 | DIMETHYLBENZIDINE, 3,3'- | o-Tolidine | 4,4'-Bi-o-toluidine | STL387858 | (1,1'-Biphenyl)-4,4'-diamine, 3,3'-dimethyl-
Specifications & Purity analytical standard, for environmental analysis, ≥99%(GC)
Storage Temp Protected from light,Room temperature
Shipped In Normal
Grade analytical standard, for environmental analysis

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Biphenyls and derivatives
Intermediate Tree Nodes Benzidines
Direct Parent 3,3'-disubstituted benzidines
Alternative Parents Aniline and substituted anilines  Aminotoluenes  Primary amines  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular Framework Aromatic homomonocyclic compounds
Substituents 3,3'-disubstituted benzidine - Aminotoluene - Aniline or substituted anilines - Toluene - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic homomonocyclic compound
Description This compound belongs to the class of organic compounds known as 3,3'-disubstituted benzidines. These are organic compounds containing a benzidine skeleton, which is substituted only at the 3- and 3'-positions.
External Descriptors biphenyls

Associated Targets(Human)

ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CXCL8 Tchem Interleukin-8 (642 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Rattus norvegicus (775804 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
clpP ATP-dependent Clp protease proteolytic subunit (245 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

IUPAC Name 4-(4-amino-3-methylphenyl)-2-methylaniline
INCHI InChI=1S/C14H16N2/c1-9-7-11(3-5-13(9)15)12-4-6-14(16)10(2)8-12/h3-8H,15-16H2,1-2H3
InChIKey NUIURNJTPRWVAP-UHFFFAOYSA-N
Smiles CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N)C)N
Isomeric SMILES CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N)C)N
WGK Germany 3
UN Number 3077
Packing Group III
Molecular Weight 212.29
Beilstein 2210640

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
E2529031 Certificate of Analysis Jun 06, 2025 T100412
E2117291 Certificate of Analysis Feb 13, 2023 T100412

Chemical and Physical Properties

Sensitivity Light sensitive.
Flash Point(°F) 471.2℉
Flash Point(°C) 244℃
Boil Point(°C) 300.5°C
Melt Point(°C) 128-131°C
Molecular Weight 212.290 g/mol
XLogP3 2.300
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 1
Exact Mass 212.131 Da
Monoisotopic Mass 212.131 Da
Topological Polar Surface Area 52.000 Ų
Heavy Atom Count 16
Formal Charge 0
Complexity 205.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Peijun Zheng, Wei Xie, Zhili Cai, Yang Jiao, Ying Sun, Tianliang Han, Xiaohua Ma, Nanwen Li, Shuangjiang Luo.  (2023)  Ionization of Tröger's base polymer of intrinsic microporosity for high-performance membrane-mediated helium recovery.  JOURNAL OF MEMBRANE SCIENCE,  672  (121425). 
2. Wan-qi Ren, Bin Ji, Zhi Kuang, Fang Fang, Xiao-Lin Guo, Zhi-Yong Wu.  (2023)  Paper-based analytical device for fast colorimetric detection of total hemoglobin and free hemoglobin from human blood sample.  MICROCHEMICAL JOURNAL,  187  (108380). 
3. Lu Han, Shuzheng Sun, Yanqin Yang, Junbo Yue, Jingde Li.  (2023)  An ultrathin double-layer covalent organic framework/zwitterionic microporous polymer functional separator for high-performance lithium-sulfur battery.  APPLIED SURFACE SCIENCE,  610  (155496). 
4. Junbo Yue, Jingjing Hou, Yixuan Li, Yanqin Yang, Lu Han, Shuzheng Sun, Jingde Li.  (2022)  Branched Tröger's base polymer membranes for gas separation.  POLYMER,  262  (125437). 
5. Jia Hui Chen, Yvonne Shuen Lann Choo, Wei Ting Gao, Xue Lang Gao, Zhi Hong Cai, Jia Jun Wang, Qiu Gen Zhang, Ai Mei Zhu, Qing Lin Liu.  (2022)  Tröger’s Base Microporous Anion Exchange Membranes with Hyperbranched Structure for Fuel Cells.  ACS Applied Energy Materials,  (9): (11797–11806). 
6. Shuzheng Sun, Lu Han, Jingjing Hou, Yanqin Yang, Junbo Yue, Guoxian Gu, Chong Yang Chuah, Jingde Li, Zisheng Zhang.  (2022)  Single-walled carbon nanotube gutter layer supported ultrathin zwitterionic microporous polymer membrane for high-performance lithium-sulfur battery.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  628  (1012). 
7. Hao Ren, Mingchen Lu, Qingquan Tang, Xianze Yin, Luoxin Wang, Hua Wang.  (2022)  Facile Preparation of Fluorine-Free, Heat-Resisting, Breathable, and Waterproof Nanofibrous Membranes from Polymers of Intrinsic Microporosity.  MACROMOLECULAR MATERIALS AND ENGINEERING,  307  (5): (2100845). 
8. Tang Hongying, Geng Kang, Wu Lei, Liu Junjie, Chen Zhiquan, You Wei, Yan Feng, Guiver Michael D., Li Nanwen.  (2022)  Fuel cells with an operational range of –20 °C to 200 °C enabled by phosphoric acid-doped intrinsically ultramicroporous membranes.  Nature Energy,  (2): (153-162). 
9. Shuzheng Sun, Congcong Li, Mingkai Li, Guoxian Gu, Yanqin Yang, jingde Li, Zisheng Zhang.  (2022)  Zwitterionic microporous polymer with selective ion transport for durable lithium-sulfur batteries.  POLYMER,  239  (124439). 
10. Guolong Huo, Shan Xu, Lei Wu, Shuanyan Kang, Zhiguang Zhang, Yanfang Fan, Nanwen Li.  (2022)  Structural engineering on copolyimide membranes for improved gas separation performance.  JOURNAL OF MEMBRANE SCIENCE,  643  (119989). 
11. Jihong Li, Yipu Liu, Hui Chen, Zhankai Zhang, Xiaoxin Zou.  (2021)  Design of a Multilayered Oxygen-Evolution Electrode with High Catalytic Activity and Corrosion Resistance for Saline Water Splitting.  ADVANCED FUNCTIONAL MATERIALS,  31  (27): (2101820). 
12. Xiang Liang, Wenhui Feng, Dong Liang, Yan Xu, Xiaoqing Qiu.  (2021)  Hydroxyl/amino and Fe(III) co-grafted graphite carbon nitride for photocatalytic removal of volatile organic compounds.  ENVIRONMENTAL RESEARCH,  197  (111044). 
13. Quanhao Shen, Lingfei Wei, Rehana Bibi, Ke Wang, Dandan Hao, Jiancheng Zhou, Naixu Li.  (2021)  Boosting photocatalytic degradation of tetracycline under visible light over hierarchical carbon nitride microrods with carbon vacancies.  JOURNAL OF HAZARDOUS MATERIALS,  413  (125376). 
14. Xiao Zhang, Qin Yang, Yunhe Lang, Xia Jiang, Peng Wu.  (2020)  Rationale of 3,3′,5,5′-Tetramethylbenzidine as the Chromogenic Substrate in Colorimetric Analysis.  ANALYTICAL CHEMISTRY,  92  (18): (12400–12406). 
15. Jiayi Zhang, Yu Zeng, Tanyang Xiao, Song Tian, Jing Jiang.  (2024)  Aerophobic/Hydrophilic Nickel–Iron Sulfide Nanoarrays for Energy-Saving Hydrogen Production from Seawater Splitting Assisted by Sulfion Oxidation Reaction.  INORGANIC CHEMISTRY,  63  (38): (17662-17671). 
16. Wenlong Jiang, Yunpeng Zhang, Peng Gao, Kewu He, Jun Yin.  (2024)  Construction of high-fidelity and multi-functional organic/inorganic aerogel composites for harsh environments.  Journal of Environmental Chemical Engineering,  12  (112560). 
17. Lunhong Ai, Yao Tian, Tanyang Xiao, Jiayi Zhang, Chenghui Zhang, Jing Jiang.  (2024)  Energy-saving hydrogen production from sulfion oxidation-hybrid seawater splitting enabled by superwettable corrosion-resistant NiFe layered double hydroxide/FeNi2S4 heterostructured nanoarrays.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  673  (607). 
18. Jing Jiang, Yao Tian, Jiayi Zhang, Chenghui Zhang, Lunhong Ai.  (2024)  Metallic Cu-incorporated NiFe layered double hydroxide nanosheets enabling energy-saving hydrogen generation from chlorine-free seawater electrolysis coupled with sulfion upcycling.  FUEL,  367  (131506). 
19. Yongchao Sun, Xudong Bi, Lu Bai, Tianyou Li, Fangxu Fan, Zeyuan Gao, Yijun Liu, Jianyu Guan, Fake Sun, Hongjin Li, Gaohong He, Canghai Ma.  (2025)  Mixed matrix membranes incorporating bromine functionalized UiO-66 in the Tröger’s base polymer for enhanced CO2 capture.  CHEMICAL ENGINEERING SCIENCE,  306  (121230). 
20. Chen Xiuling, Chen Guining, Xie Cong, Wu Lei, Liu Gongping, Li Nanwen, Jin Wanqin.  (2025)  Polyolefin reweaved ultra-micropore membrane for CO2 capture.  Nature Communications,  16  (1): (1-10). 
21. Zhengpeng Chen, Xin He, Zhengshuai Cao, Yunfan Li, Denglong Chen, Zhiwang Yang, Ziqiang Lei.  (2024)  Syringaldehyde-DOPO derivative for enhancing flame retardancy and mechanical properties of epoxy resin.  FIRE AND MATERIALS,  48  (7): (752-764). 
22. Meng Wang, Tingting Huang, Meng Shan, Mei Sun, Shasha Liu, Hai Tang.  (2024)  Zwitterionic Tröger’s Base Microfiltration Membrane Prepared via Vapor-Induced Phase Separation with Improved Demulsification and Antifouling Performance.  MOLECULES,  29  (5): (1001). 

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