Skip to the beginning of the images gallery

NS 5806 - ≥99%(HPLC), high purity , CAS No.426834-69-7

Grade & Purity:

≥99%(HPLC)

Cas Number: 426834-69-7
Molecular Weight: 574.07
PubChem CID: 11642685

In stock

Item Number

N287207

Grouped product items
SKU	Size	Availability	Price
N287207-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$117.90
N287207-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$187.90
N287207-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$423.90
N287207-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$761.90
N287207-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,370.90

KV4.3 channel activator

View related series

Ion Channels (3) Membrane Transporter/Ion Channel (1822) Pharmacology (7) Potassium Channel (253) Potassium Channels (4) Voltage-gated Potassium (KV) Channel Activators (1) Voltage-gated Potassium (KV) Channels (1)

Synonyms	CCG-221844 \| BCP33045 \| NS 5806; NS5806 \| DTXSID30469888 \| MolPort-023-277-083 \| CS-0029257 \| NCGC00371032-03 \| NS5806, >=98% (HPLC) \| EX-A7052 \| NS 5806 \| NS5806 \| NS-5806 \| 1-[3,5-bis(trifluoromethyl)phenyl]-3-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]ure
Specifications & Purity	≥99%(HPLC)
Biochemical and Physiological Mechanisms	KV4.3 channel activator; mediates the transient outward K+current (Ito). Increases IKv4.3peak current amplitude in CHO-K1 cells expressing KV4.3 and KChIP2 (EC50= 5.3μM). Inhibits KV1.4-mediated currents independently of KChIP2. Also slows the decay of KV
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Azoles
Subclass	Tetrazoles
Intermediate Tree Nodes	Not available
Direct Parent	Phenyltetrazoles and derivatives
Alternative Parents	Trifluoromethylbenzenes N-phenylureas Bromobenzenes Aryl bromides Heteroaromatic compounds Ureas Azacyclic compounds Organonitrogen compounds Organofluorides Organobromides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Phenyltetrazole - Trifluoromethylbenzene - N-phenylurea - Bromobenzene - Halobenzene - Aryl bromide - Aryl halide - Monocyclic benzene moiety - Benzenoid - Heteroaromatic compound - Urea - Azacycle - Organofluoride - Organobromide - Organohalogen compound - Organooxygen compound - Alkyl fluoride - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Alkyl halide - Organonitrogen compound - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as phenyltetrazoles and derivatives. These are compounds containing a phenyltetrazole skeleton, which consists of a tetrazole bound to a phenyl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

IUPAC Name	1-[3,5-bis(trifluoromethyl)phenyl]-3-[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea
INCHI	InChI=1S/C16H8Br2F6N6O/c17-8-4-10(13-27-29-30-28-13)12(11(18)5-8)26-14(31)25-9-2-6(15(19,20)21)1-7(3-9)16(22,23)24/h1-5H,(H2,25,26,31)(H,27,28,29,30)
InChIKey	UZWJWROOLOOCPQ-UHFFFAOYSA-N
Smiles	C1=C(C=C(C=C1C(F)(F)F)NC(=O)NC2=C(C=C(C=C2Br)Br)C3=NNN=N3)C(F)(F)F
Isomeric SMILES	C1=C(C=C(C=C1C(F)(F)F)NC(=O)NC2=C(C=C(C=C2Br)Br)C3=NNN=N3)C(F)(F)F
Molecular Weight	574.07
Reaxy-Rn	37982961
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=37982961&ln=

Solubility	Solvent:DMSO, Max Conc. mg/mL: 57.41, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 28.7, Max Conc. mM: 50
Molecular Weight	574.070 g/mol
XLogP3	4.800
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	10
Rotatable Bond Count	3
Exact Mass	573.901 Da
Monoisotopic Mass	571.903 Da
Topological Polar Surface Area	95.600 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	619.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

NS 5806 - ≥99%(HPLC), high purity , CAS No.426834-69-7

Basic Description

Taxonomic Classification

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Chemical and Physical Properties

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reviews

Customer Reviews