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Nicosulfuron - 95%, high purity , CAS No.111991-09-4

    Grade & Purity:
  • ≥95%
In stock
Item Number
N118531
Grouped product items
SKU Size
Availability
Price Qty
N118531-25g
25g
3
$137.90

Basic Description

Synonyms Nicosulfuron, PESTANAL(R), analytical standard | 2-(N-((4,6-Dimethoxypyrimidin-2-yl)carbamoyl)sulfamoyl)-N,N-dimethylnicotinamide | 2-[[[[(4,6-Dimethoxy-2-pyrimidinyl)amino]carbonyl]amino]sulfonyl]-N,N-dimethyl-3-pyridinecarboxamide | AKOS015851875 | Mila
Specifications & Purity ≥95%
Shipped In Normal

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Pyridines and derivatives
Subclass Pyridinesulfonamides
Intermediate Tree Nodes Not available
Direct Parent Pyridinesulfonamides
Alternative Parents Nicotinamides  Sulfonylureas  Alkyl aryl ethers  Pyrimidines and pyrimidine derivatives  Tertiary carboxylic acid amides  Organosulfonic acids and derivatives  Heteroaromatic compounds  Aminosulfonyl compounds  Propargyl-type 1,3-dipolar organic compounds  Carboximidic acids and derivatives  Azacyclic compounds  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Pyridine-2-sulfonamide - Nicotinamide - Pyridinecarboxamide - Pyridine carboxylic acid or derivatives - Alkyl aryl ether - Sulfonylurea - Pyrimidine - Heteroaromatic compound - Organic sulfonic acid or derivatives - Aminosulfonyl compound - Tertiary carboxylic acid amide - Sulfonyl - Organosulfonic acid or derivatives - Carboxamide group - Carboximidic acid derivative - Carboxylic acid derivative - Ether - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organosulfur compound - Organic oxide - Hydrocarbon derivative - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as pyridinesulfonamides. These are heterocyclic compounds containing a pyridine ring substituted by one or more sulfonamide groups.
External Descriptors Sulfonylurea herbicides

Associated Targets(non-human)

Echinochloa crus-galli (3685 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Sorghum halepense (127 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Zea mays (820 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Avena fatua (609 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Setaria viridis (435 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Abutilon theophrasti (831 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Chenopodium album (769 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Digitaria sanguinalis (1594 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Sida spinosa (38 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Xanthium strumarium (250 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cynodon dactylon (28 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Stellaria media (151 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Portulaca oleracea (78 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Commelina communis (11 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Elymus repens (18 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Capsella bursa-pastoris (46 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Persicaria lapathifolia (57 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Muhlenbergia (20 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Eleusine indica (140 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cyperus rotundus (46 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Persicaria longiseta (53 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cyperus microiria (4 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Senna tora (12 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Solanum nigrum (20 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Amaranthus viridis (153 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504754698
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504754698
IUPAC Name 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide
INCHI InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)
InChIKey RTCOGUMHFFWOJV-UHFFFAOYSA-N
Smiles CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC
Isomeric SMILES CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC
WGK Germany 1
RTECS US4615000
UN Number 3077
Packing Group III
Molecular Weight 410.41
Reaxy-Rn 7233432
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7233432&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number Certificate Type Date Item
G2028129 Certificate of Analysis May 08, 2024 N118531

Chemical and Physical Properties

Solubility 400mg/kg water (pH buffered, final pH 5.01), 120g/kg (pH7 buffered, final pH 6.85), 39.2g/kg (pH9 buffered, final pH 8.8), solubility in organic solvents (g/kg): acetone 18, acetonitrile 23, chloroform and dimethylformamide 64, dichloromethane 160, ethano
Melt Point(°C) 142°C
Molecular Weight 410.400 g/mol
XLogP3 0.600
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 9
Rotatable Bond Count 6
Exact Mass 410.101 Da
Monoisotopic Mass 410.101 Da
Topological Polar Surface Area 161.000 Ų
Heavy Atom Count 28
Formal Charge 0
Complexity 642.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Qingyun Ma, Qingqing Li, Jie Wang, Rebecca E. Parales, Lin Li, Zhiyong Ruan.  (2023)  Exposure to three herbicide mixtures influenced maize root-associated microbial community structure, function and the network complexity.  ENVIRONMENTAL POLLUTION,  336  (122393). 
2. Ruiyu Fu, Tingze Ren, Yanhui Zhang, Xiaoli Guo, Xin Di.  (2023)  A new sample treatment strategy based on supramolecular solvent for determination of herbicide residues in water samples by Box-Behnken design.  MICROCHEMICAL JOURNAL,  187  (108390). 
3. Ting Zhao, Xiaochen Liang, Xinjie Guo, Xingjie Yang, Jialiang Guo, Xia Zhou, Xueqin Huang, Wenqian Zhang, Yiqing Wang, Zhaowei Liu, Zhengjin Jiang, Hongke Zhou, Haibo Zhou.  (2023)  Smartphone-based colorimetric sensor array using gold nanoparticles for rapid distinguishment of multiple pesticides in real samples.  FOOD CHEMISTRY,  404  (134768). 
4. Jianan Liu, Jinjin Cheng, Chunli Zhou, Liya Ma, Xiaolong Chen, Yong Li, Xing Sun, Xiaolong Yan, Renhua Geng, Qun Wan, Xiangyang Yu.  (2023)  Uptake kinetics and subcellular distribution of three classes of typical pesticides in rice plants.  SCIENCE OF THE TOTAL ENVIRONMENT,  858  (159826). 
5. Li Miaomiao, Li Qingqing, Yao Jun, Sunahara Geoffrey, Duran Robert, Zhang Qinghua, Ruan Zhiyong.  (2022)  Transcriptomic response of Pseudomonas nicosulfuronedens LAM1902 to the sulfonylurea herbicide nicosulfuron.  Scientific Reports,  12  (1): (1-13). 
6. Xiaoli Guo, Tingze Ren, Jianchun Ji, Yan Yang, Xin Di.  (2022)  An alternative analytical strategy based on QuEChERS and dissolvable layered double hydroxide dispersive micro-solid phase extraction for trace determination of sulfonylurea herbicides in wolfberry by LC–MS/MS.  FOOD CHEMISTRY,  396  (133652). 
7. Qingyun Ma, Hao Tan, Jinlong Song, Miaomiao Li, Zhiye Wang, Rebecca E. Parales, Lin Li, Zhiyong Ruan.  (2022)  Effects of long-term exposure to the herbicide nicosulfuron on the bacterial community structure in a factory field.  ENVIRONMENTAL POLLUTION,  307  (119477). 
8. Yuan-Yuan Zhang, Shuang Gao, Minh-Tu Hoang, Zi-Wei Wang, Xin Ma, Yue Zhai, Na Li, Li-Xia Zhao, Ying Fu, Fei Ye.  (2020)  Protective efficacy of phenoxyacetyl oxazolidine derivatives as safeners against nicosulfuron toxicity in maize.  PEST MANAGEMENT SCIENCE,  77  (1): (177-183). 
9. Liang Ting, Gao Lei, Qin Dongli, Chen Ligang.  (2019)  Determination of Sulfonylurea Herbicides in Grain Samples by Matrix Solid-Phase Dispersion with Mesoporous Structured Molecularly Imprinted Polymer.  Food Analytical Methods,  12  (9): (1938-1948). 
10. Shan Zhou, Jinlong Song, Weiwei Dong, Yingchun Mu, Qi Zhang, Ziwen Fan, Yanwei Wang, Delong Kong, Yiqing Zhou, Xu Jiang, Bin Zhao, Gang Han, Zhiyong Ruan.  (2017)  Nicosulfuron Biodegradation by a Novel Cold-Adapted Strain Oceanisphaera psychrotolerans LAM-WHM-ZC.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  65  (47): (10243–10249). 
11. Zhang Hui, Li Mengya, Li Jie, Wang Guangli, Liu Yuan.  (2017)  Purification and properties of a novel quizalofop-p-ethyl-hydrolyzing esterase involved in quizalofop-p-ethyl degradation by Pseudomonas sp. J-2.  Microbial Cell Factories,  16  (1): (1-10). 
12. Hui Zhang, Mengya Li, Jie Li, Guangli Wang, Feng Li, Dayong Xu, Yuan Liu, Minghua Xiong.  (2017)  A key esterase required for the mineralization of quizalofop-p-ethyl by a natural consortium of Rhodococcus sp. JT-3 and Brevundimonas sp. JT-9.  JOURNAL OF HAZARDOUS MATERIALS,  327  (1). 
13. Xiaoxiao You, Ligang Chen.  (2016)  Analysis of sulfonylurea herbicides in grain samples using molecularly imprinted polymers on the surface of magnetic carbon nanotubes by extraction coupled with HPLC.  Analytical Methods,  (5): (1003-1012). 
14. Zhengyuan Gao, Chenggang Gu, Xiuli Fan, Lezu Shen, Zhihua Jin, Fang Wang, Xin Jiang.  (2024)  Biochemical insights into the biodegradation mechanism of typical sulfonylureas herbicides and association with active enzymes and physiological response of fungal microbes: A multi-omics approach.  ENVIRONMENT INTERNATIONAL,  190  (108906). 
15. Qianhang Zhai, Yue Liu, Lining Zheng, Yufeng Xiao, Yulin Wu, Hao Zhang, Jingyuan Chen.  (2025)  Elucidation of molecular mechanisms underlying degradation of nicosulfuron and its derivative by Klebsiella jilinsis 2N3 using multiomic analysis.  JOURNAL OF HAZARDOUS MATERIALS,  490  (137838). 
16. Yufei Dai, Xianli Song, Jing Zhao, Limin Wang, Xiaoru Cui, Li Lu, Jingyu Zhang, Haoyu Zhang, Dahai Zhang, Keqiang Li.  (2025)  Spatiotemporal distribution and potential ecological risks of current-use pesticides (CUPs) in Laizhou Bay, China.  MARINE ENVIRONMENTAL RESEARCH,  206  (107042). 

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