This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
Nemadectin, initially described as LL-F28249-a, is a macrocyclic lactone antibiotic demonstrating broad-spectrum endectocidal and nematocidal activity. Nemadectin bears structural similarity to the milbemycin and avermectin antibiotics, differing by the unsaturated side-chain extending from the 6,6-spiroketal core of the antibiotic. Nemadectin has demonstrated efficacy against the natural canine-infecting helminths and against ivermectin-resistant|Haemonchus contortus|in sheep.
This compound belongs to the class of organic compounds known as milbemycins. These are a group of macrolides with a structure containing a 16-membered lactone ring fused to a 1,7-dioxaspiroundecane ring system and to either a benzofuran (or hydrogenated derivative thereof). In some cases (e.g. Milbemycin E), the tetrahydrofuranyl ring is missing. Milbemycins can be o-glycosylated at C13 to form Avermectins. Milbemycins are produced by Streptomyces species.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
