Skip to the beginning of the images gallery

Nefopam HCl - ≥98%, high purity , CAS No.23327-57-3

1 Citations

COA

Grade & Purity:

≥98%

Cas Number: 23327-57-3
Molecular Weight: 289.8
EC Number: 245-585-5
MDL number: MFCD00012750
PubChem CID: 155290
PubChem SID: 504757403

In stock

Item Number

N129546

Grouped product items
SKU	Size	Availability	Price
N129546-5g	5g	10	$46.90
N129546-25g	25g	5	$209.90
N129546-100g	100g	2	$754.90

Centrally-acting, non-opioid analgesic drug

View related series

Pharmaceutical ingredients (367)

Basic Description

Synonyms	MFCD00012750 \| Q27264216 \| 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine hydrochloride \| DTXCID5025441 \| MFCD00000909 \| 1H-2,5-BENZOXAZOCINE, 5-METHYL-1-PHENYL-3,4,5,6-TETRAHYDRO-, HYDROCHLORIDE \| BCP13749 \| Pallopikeron \| CAS-23327-57-3
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Nefopam is a centrally-acting analgesic drug of the benzoxazocine chemical class. Nefopam is a non-opioid, but has a potentiating effect on morphine and other opioids. Its mechanism of action is not certain, but may involve its action as a dopamine/seroto
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic nitrogen compounds
  - Class Organonitrogen compounds
    - Subclass Amines

Kingdom	Organic compounds
Superclass	Organic nitrogen compounds
Class	Organonitrogen compounds
Subclass	Amines
Intermediate Tree Nodes	Not available
Direct Parent	Aralkylamines
Alternative Parents	Benzene and substituted derivatives Trialkylamines Oxacyclic compounds Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organic chloride salts Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Aralkylamine - Monocyclic benzene moiety - Benzenoid - Tertiary amine - Tertiary aliphatic amine - Dialkyl ether - Ether - Oxacycle - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Organic salt - Organic chloride salt - Organooxygen compound - Hydrocarbon derivative - Organopnictogen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as aralkylamines. These are alkylamines in which the alkyl group is substituted at one carbon atom by an aromatic hydrocarbyl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

ampC Beta-lactamase AmpC (62480 Activities)

Discover Target: ampC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

fba Putative fructose-1,6-bisphosphate aldolase (15559 Activities)

Discover Target: fba

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504757403
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504757403
IUPAC Name	5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine;hydrochloride
INCHI	InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H
InChIKey	CNNVSINJDJNHQK-UHFFFAOYSA-N
Smiles	CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3.Cl
Isomeric SMILES	CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3.Cl
WGK Germany	3
Molecular Weight	289.8
Reaxy-Rn	3575294
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3575294&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number	Certificate Type	Date	Item
J1921046	Certificate of Analysis	Feb 08, 2025	N129546
E2309669	Certificate of Analysis	Feb 07, 2025	N129546
E2309673	Certificate of Analysis	Feb 07, 2025	N129546
E2309606	Certificate of Analysis	Feb 07, 2025	N129546
E2309558	Certificate of Analysis	Feb 07, 2025	N129546
E2309555	Certificate of Analysis	Feb 07, 2025	N129546
E2309480	Certificate of Analysis	Feb 07, 2025	N129546
F1721042	Certificate of Analysis	Jan 26, 2023	N129546
L2216926	Certificate of Analysis	Dec 22, 2022	N129546

Chemical and Physical Properties

Solubility	DMSO 1 mg/mL Water 21 mg/mL Ethanol <1 mg/mL
Sensitivity	heat sensitive
Melt Point(°C)	260°C
Molecular Weight	289.800 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	1
Exact Mass	289.123 Da
Monoisotopic Mass	289.123 Da
Topological Polar Surface Area	12.500 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	274.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Xiaofei Ma, Zhenyu Fan, Zhiyuan Tang, Liangliang Cai. (2024) Investigation on improvement of enantioseparation based on clindamycin phosphate by chiral deep eutectic solvents in capillary electrophoresis. JOURNAL OF SEPARATION SCIENCE, 47 (3): (2300847).

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions, always use the batch-specific molecular weight of the product found on the vial label and the Certificate of Analysis (available online).

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator enables you to quickly determine the volume of a reagent needed to reconstitute your vial. Just enter the mass of the reagent and the target concentration, and the calculator will do the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration