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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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N276424-1mg
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1mg |
2
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$41.90
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N276424-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$158.90
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N276424-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$318.90
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|
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N276424-50mg
|
50mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,584.90
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Antibiotic
| Synonyms | Nanchangmycin A | Sodium;(E,2S,4R,8S)-8-[(2S,5R,7S,8R,9R)-7-hydroxy-2-[(2R,4S,5S,7R,9S,10R)-2-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-9-[(2S,5S,6R)-5-methoxy-6-methyloxan-2-yl]oxy-4,10-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-2,8- |
|---|---|
| Specifications & Purity | ≥98% |
| Biochemical and Physiological Mechanisms | Antibiotic. Polyether ionophore similar to dianemycin. Active against Gram-positive bacteria. |
| Storage Temp | Store at -20°C,Desiccated |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Fatty Acyls |
| Subclass | Fatty acids and conjugates |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Medium-chain fatty acids |
| Alternative Parents | Hydroxy fatty acids Ketals Unsaturated fatty acids Oxanes Alpha-branched alpha,beta-unsaturated ketones Acryloyl compounds Oxolanes Enones Secondary alcohols Carboxylic acid salts Hemiacetals Ketones Oxacyclic compounds Carboxylic acids Dialkyl ethers Monocarboxylic acids and derivatives Primary alcohols Aldehydes Organic sodium salts Organic oxides Hydrocarbon derivatives Organic zwitterions |
| Molecular Framework | Aliphatic heteropolycyclic compounds |
| Substituents | Medium-chain fatty acid - Hydroxy fatty acid - Ketal - Oxane - Unsaturated fatty acid - Alpha-branched alpha,beta-unsaturated-ketone - Enone - Oxolane - Acryloyl-group - Alpha,beta-unsaturated ketone - Carboxylic acid salt - Hemiacetal - Ketone - Secondary alcohol - Carboxylic acid derivative - Carboxylic acid - Organoheterocyclic compound - Acetal - Dialkyl ether - Monocarboxylic acid or derivatives - Organic alkali metal salt - Ether - Oxacycle - Alcohol - Organic oxygen compound - Organic sodium salt - Organooxygen compound - Primary alcohol - Hydrocarbon derivative - Aldehyde - Carbonyl group - Organic salt - Organic oxide - Organic zwitterion - Aliphatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as medium-chain fatty acids. These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. |
| External Descriptors | Not available |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 504772478 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772478 |
| IUPAC Name | sodium;(E,2S,4R,8S)-8-[(2S,5R,7S,8R,9R)-7-hydroxy-2-[(2R,4S,5S,7R,9S,10R)-2-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-9-[(2S,5S,6R)-5-methoxy-6-methyloxan-2-yl]oxy-4,10-dimethyl-1,6-dioxaspiro[4.5]decan-7-yl]-2,8-dimethyl-1,10-dioxaspiro[4.5]decan-9-yl]-2,4,6-trimethyl-5-oxonon-6-enoate |
| INCHI | InChI=1S/C47H78O14.Na/c1-24(40(50)25(2)18-28(5)43(51)52)17-26(3)41-31(8)34(49)22-45(59-41)16-15-44(11,61-45)38-21-36(56-39-14-13-35(54-12)33(10)55-39)32(9)47(58-38)30(7)20-37(57-47)42-27(4)19-29(6)46(53,23-48)60-42;/h17,25-39,41-42,48-49,53H,13-16,18-23H2,1-12H3,(H,51,52);/q;+1/p-1/b24-17+;/t25-,26+,27+,28+,29-,30+,31-,32-,33-,34+,35+,36+,37-,38-,39-,41-,42+,44+,45-,46+,47+;/m1./s1 |
| InChIKey | XMAIRYYXDCNFKP-SEDNIUBGSA-M |
| Smiles | CC1CC(C(OC1C2CC(C3(O2)C(C(CC(O3)C4(CCC5(O4)CC(C(C(O5)C(C)C=C(C)C(=O)C(C)CC(C)C(=O)[O-])C)O)C)OC6CCC(C(O6)C)OC)C)C)(CO)O)C.[Na+] |
| Isomeric SMILES | C[C@H]1C[C@H]([C@@](O[C@@H]1[C@H]2C[C@@H]([C@@]3(O2)[C@@H]([C@H](C[C@@H](O3)[C@@]4(CC[C@@]5(O4)C[C@@H]([C@H]([C@H](O5)[C@@H](C)/C=C(\C)/C(=O)[C@H](C)C[C@H](C)C(=O)[O-])C)O)C)O[C@@H]6CC[C@@H]([C@H](O6)C)OC)C)C)(CO)O)C.[Na+] |
| PubChem CID | 86278937 |
| Molecular Weight | 889.1 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 10, 2023 | N276424 | |
| Certificate of Analysis | Feb 10, 2023 | N276424 | |
| Certificate of Analysis | Feb 10, 2023 | N276424 | |
| Certificate of Analysis | Feb 10, 2023 | N276424 |
| Solubility | DMSO 173 mg/mL (194.57 mM),water <1 mg/mL (<1 mM),Ethanol 173 mg/mL (194.57 mM) |
|---|---|
| Molecular Weight | 889.100 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 13 |
| Exact Mass | 888.521 Da |
| Monoisotopic Mass | 888.521 Da |
| Topological Polar Surface Area | 192.000 Ų |
| Heavy Atom Count | 62 |
| Formal Charge | 0 |
| Complexity | 1580.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 21 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 2 |
| 1. Yu-Si Yan, Li-Sha Zou, He-Geng Wei, Meng-Yao Yang, Yun-Qi Yang, Xiao-Fang Li, Hai-Yang Xia. (2023) An atypical two-component system, AtcR/AtcK, simultaneously regulates the biosynthesis of multiple secondary metabolites in Streptomyces bingchenggensis. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, |