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NAD 299 hydrochloride - ≥98%(HPLC), high purity , CAS No.184674-99-5

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 184674-99-5
Molecular Weight: 354.85
PubChem CID: 90488823
PubChem SID: 504772601

In stock

Item Number

N288009

Grouped product items
SKU	Size	Availability	Price
N288009-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$29.90
N288009-5mg	5mg	2	$104.90
N288009-10mg	10mg	2	$160.90

Selective, high affinity 5-HT1Aantagonist

View related series

Class A GPCR (4138)

Basic Description

Synonyms	(3R)-3-(Dicyclobutylamino)-8-fluoro-3,4-dihydro-2H-1-benzopyran-5-carboxamide hydrochloride
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Selective, high affinity 5-HT1Areceptor antagonist (Ki= 0.6 nMin vitro). Enhances the action of selective 5-HT reuptake inhibitors and reversescitalopram-induced inhibition of serotonergic cell firing.
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Benzopyrans
    - Subclass 1-benzopyrans

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Benzopyrans
Subclass	1-benzopyrans
Intermediate Tree Nodes	Not available
Direct Parent	1-benzopyrans
Alternative Parents	4-halobenzoic acids and derivatives Aralkylamines Alkyl aryl ethers Aryl fluorides Trialkylamines Primary carboxylic acid amides Amino acids and derivatives Oxacyclic compounds Organofluorides Organic oxides Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	4-halobenzoic acid or derivatives - Halobenzoic acid or derivatives - 1-benzopyran - Alkyl aryl ether - Aralkylamine - Aryl fluoride - Aryl halide - Benzenoid - Amino acid or derivatives - Carboxamide group - Primary carboxylic acid amide - Tertiary amine - Tertiary aliphatic amine - Ether - Carboxylic acid derivative - Oxacycle - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Amine - Organic oxide - Organic oxygen compound - Hydrocarbon derivative - Hydrochloride - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as 1-benzopyrans. These are organic aromatic compounds that 1-benzopyran, a bicyclic compound made up of a benzene ring fused to a pyran, so that the oxygen atom is at the 1-position.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504772601
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504772601
IUPAC Name	(3R)-3-[di(cyclobutyl)amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide;hydrochloride
INCHI	InChI=1S/C18H23FN2O2.ClH/c19-16-8-7-14(18(20)22)15-9-13(10-23-17(15)16)21(11-3-1-4-11)12-5-2-6-12;/h7-8,11-13H,1-6,9-10H2,(H2,20,22);1H/t13-;/m1./s1
InChIKey	GSZJANKLCPHEEX-BTQNPOSSSA-N
Smiles	C1CC(C1)N(C2CCC2)C3CC4=C(C=CC(=C4OC3)F)C(=O)N.Cl
Isomeric SMILES	C1CC(C1)N([C@@H]2CC3=C(C=CC(=C3OC2)F)C(=O)N)C4CCC4.Cl
PubChem CID	90488823
Molecular Weight	354.85

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Date	Item
H2218272	Certificate of Analysis	Jun 10, 2025	N288009
H2218273	Certificate of Analysis	Jun 10, 2025	N288009
L2413214	Certificate of Analysis	Jul 14, 2022	N288009

Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 35.48, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 35.48, Max Conc. mM: 100
Molecular Weight	354.800 g/mol
XLogP3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	4
Exact Mass	354.151 Da
Monoisotopic Mass	354.151 Da
Topological Polar Surface Area	55.600 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	438.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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