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N6-Ethyladenosine - 99%, high purity , CAS No.14357-08-5

COA

Grade & Purity:

≥99%

Cas Number: 14357-08-5
Molecular Weight: 295.29
PubChem CID: 15160100

In stock

Item Number

N651026

Grouped product items
SKU	Size	Availability	Price	Qty
N651026-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90
N651026-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$450.90

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Adenosine Receptor (113) Class A GPCR (4138) GPCR/G Protein (3172)

Basic Description

Synonyms	NSC-516603 \| n6-ethyladenosine \| Adenosine, N-ethyl- \| (2R,3R,4S,5R)-2-(6-(Ethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol \| HY-111809 \| MS-24224 \| Z1980898342 \| SCHEMBL6758546 \| 5D56H6D7ZZ \| AKOS030575552 \| N-Ethyladenosine \| CS-0092
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with K i s of 4.9 and 4.7 nM for hA 1 AR and hA 3 AR, respectively.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with K i s of 4.9 and 4.7 nM for hA 1 AR and hA 3 AR, respectively In Vitro N6-Ethyladenosine (Compound 28) exhibits more selectivity at hA 1 AR and hA 3 AR over hA 2 AR (K i , 8900±770 nM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Ki: 4.9 nM (hA 1 AR), 4.7 nM (hA 3 AR)

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Nucleosides, nucleotides, and analogues
  - Class Purine nucleosides

Kingdom	Organic compounds
Superclass	Nucleosides, nucleotides, and analogues
Class	Purine nucleosides
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Purine nucleosides
Alternative Parents	Glycosylamines 6-alkylaminopurines Pentoses Aminopyrimidines and derivatives N-substituted imidazoles Imidolactams Oxolanes Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary alcohols Hydrocarbon derivatives Amines
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Purine nucleoside - Glycosyl compound - N-glycosyl compound - 6-alkylaminopurine - 6-aminopurine - Pentose monosaccharide - Purine - Imidazopyrimidine - Aminopyrimidine - Imidolactam - Pyrimidine - N-substituted imidazole - Monosaccharide - Heteroaromatic compound - Oxolane - Azole - Imidazole - Secondary alcohol - Organoheterocyclic compound - Oxacycle - Azacycle - Hydrocarbon derivative - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Alcohol - Amine - Primary alcohol - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as purine nucleosides. These are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(2R,3R,4S,5R)-2-[6-(ethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
INCHI	InChI=1S/C12H17N5O4/c1-2-13-10-7-11(15-4-14-10)17(5-16-7)12-9(20)8(19)6(3-18)21-12/h4-6,8-9,12,18-20H,2-3H2,1H3,(H,13,14,15)/t6-,8-,9-,12-/m1/s1
InChIKey	SHXVYOLWYFZWKE-WOUKDFQISA-N
Smiles	CCNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O
Isomeric SMILES	CCNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
Alternate CAS	14357-08-5
PubChem CID	15160100
Molecular Weight	295.29

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : ≥ 83.33 mg/mL (282.20 mM)
Molecular Weight	295.290 g/mol
XLogP3	0.000
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	295.128 Da
Monoisotopic Mass	295.128 Da
Topological Polar Surface Area	126.000 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	363.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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