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N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide - 97%, high purity , CAS No.77377-52-7
Basic Description
Synonyms
Acetamide, N-((1,1-dimethylethyl)dimethylsilyl)-2,2,2-trifluoro-N-methyl- | Acetamide, N-[(1,1-dimethylethyl)dimethylsilyl]-2,2,2-trifluoro-N-methyl- | n-methyl-n-t-butyldimethylsilyltrifluoroacetamide | SY049326 | N-tert-Butyldimethylsilyl-N-methyltriflu
Specifications & Purity
≥97%
Storage Temp
Store at 2-8°C,Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
Application
N - tert -butyldimethylsilyl- N -methyltrifluoroacetamide (MTBSTFA) can be used as an efficient silylating agent for different alcohols, thiols, phenols, carboxylic acids, amines, and amides. It can also be used to functionalize multi-walled carbon nanotubes (MWCNTs) with polar groups. MTBSTFA is reportedly much less moisture-sensitive than other silylating reagents used for GLC derivatization.
Taxonomic Classification
Kingdom
Organic compounds
Superclass
Organometallic compounds
Class
Organometalloid compounds
Subclass
Organosilicon compounds
Intermediate Tree Nodes
Organoheterosilanes
Direct Parent
Trialkylheterosilanes
Alternative Parents
Organic metalloid salts N-silyl compounds Carboxylic acids and derivatives Organopnictogen compounds Organonitrogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides
Molecular Framework
Aliphatic acyclic compounds
Substituents
Trialkylheterosilane - Carboxylic acid derivative - Organic metalloid salt - N-silyl compound - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Alkyl fluoride - Organic salt - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Alkyl halide - Aliphatic acyclic compound
Description
This compound belongs to the class of organic compounds known as trialkylheterosilanes. These are organoheterosilanes, bearing a silicon atom linked to three alkyl groups and one heteroatom.
External Descriptors
organofluorine compound - monocarboxylic acid amide - N-silyl compound
Data sources
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Names and Identifiers
Pubchem Sid
504760873
Pubchem Sid Url
https://pubchem.ncbi.nlm.nih.gov/substance/504760873
IUPAC Name
N-[tert-butyl(dimethyl)silyl]-2,2,2-trifluoro-N-methylacetamide
INCHI
InChI=1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3
InChIKey
QRKUHYFDBWGLHJ-UHFFFAOYSA-N
Smiles
CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F
Isomeric SMILES
CC(C)(C)[Si](C)(C)N(C)C(=O)C(F)(F)F
WGK Germany
3
Molecular Weight
241.33
Beilstein
3606546
Reaxy-Rn
3606546
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3606546&ln=
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
Sensitivity
Moisture sensitive
Refractive Index
1.402
Flash Point(°F)
52℃(125°F)
Flash Point(°C)
52℃(125°F)
Boil Point(°C)
168-170°C
Molecular Weight
241.330 g/mol
XLogP3
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
2
Exact Mass
241.111 Da
Monoisotopic Mass
241.111 Da
Topological Polar Surface Area
20.300 Ų
Heavy Atom Count
15
Formal Charge
0
Complexity
255.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
0
Covalently-Bonded Unit Count
1
Citations of This Product
1.
Can Xie, Wei Ni, Fei Liu, Gangtian Zhu, Yuguang Hou.
(2023)
Analysis, distribution and evolution of individual carboxylic acids in crude oil during biodegradation. ORGANIC GEOCHEMISTRY,
178
(104573).
2.
Wei Ni, Gangtian Zhu, Fei Liu, Can Xie, Wei Li, Shukui Zhu.
(2022)
Rapid profiling of carboxylic acids in reservoir biodegraded crude oils using gas purge microsyringe extraction coupled to comprehensive two-dimensional gas chromatography-mass spectrometry. FUEL,
316
(123312).
3.
Xuejing Li, Yan Hui, Bingfeng Leng, Junli Ren, Yanni Song, Lianqiang Che, Xi Peng, Baojia Huang, Songling Liu, Lin Li, Dennis Sandris Nielsen, Yong Li, Xiaoshuang Dai, Shancen Zhao.
(2021)
Millet-based supplement restored gut microbial diversity of acute malnourished pigs. PLoS One,
16
(4):
(e0250423).
4.
Gangtian Zhu, Fei Liu, Peiyang Li, Sheng He, Shukui Zhu, Qiang Gao, Yuqi Feng.
(2019)
Profiling free fatty acids in edible oils via magnetic dispersive extraction and comprehensive two-dimensional gas chromatography-mass spectrometry. FOOD CHEMISTRY,
297
(124998).
5.
Gang-Tian Zhu, Fei Liu, Sheng He, Xiao-Mei He, Shu-Kui Zhu, Yu-Qi Feng.
(2018)
Magnetic extractant with an Fe3O4@SiO2 core and aqueous ammonia coating for microextraction of petroleum acids. RSC Advances,
8
(35):
(19486-19493).
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5 Citations
C2511665