Ceramides play a key role in regulating various cellular processes like senescence and apoptosis.They are directly involved in the proliferation and differentiation of skin cells and regulate skin barrier functionality.Ceramide based analogs are potential
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
Ceramide synthesis is mediated either by the salvage pathway by the acylation of sphingosine or sphingolipids hydrolysis or by de novo pathway via dihydroceramide formation. Structurally, ceramides have a sphingoid base, a long-chain amino alcohol linked to fatty acid by an amide bond.
Application：
C17 Ceramide (d18:1/17:0) has been used: as an internal standard for myocardial ceramide quantification using chromatography with negative ion electrospray ionization coupled to tandem mass spectrometry；as an internal standard in tandem mass spectrometry (MS/MS)；as a substrate for sphingomyelin synthase 2 enzyme
This compound belongs to the class of organic compounds known as long-chain ceramides. These are ceramides bearing a long chain fatty acid.
External Descriptors
N-acylsphingosines (ceramides)
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
B2524108