This is a demo store. No orders will be fulfilled.

N-Ethylmaleimide - Ultra pure,99.0%, high purity , CAS No.128-53-0

In stock
Item Number
E100553
Grouped product items
SKU Size
Availability
Price Qty
E100553-1g
1g
10
$13.90
E100553-5g
5g
≥10
$43.90
E100553-25g
25g
6
$146.90
E100553-100g
100g
2
$399.90

Basic Description

Synonyms NEM | maleic acid N-ethylimide | NSC92547 | NSC-92547 | USAF B-121 | ethylmaleimide | HSCI1_000382 | N-ethylmaleimide | 1-Ethyl-1H-pyrrole-2,5-dione | EU-0100492 | GTPL5335 | N-Ethylmaleimide, purum p.a., >=99.0% (HPLC) | MFCD00005509 | NCGC00015415-04 |
Specifications & Purity Moligand™, Ultra pure, ≥99%
Biochemical and Physiological Mechanisms Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels. Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.
Storage Temp Store at 2-8°C,Argon charged
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™, Ultra pure
Product Description

Reagent for the covalent modification of cysteine residues in proteins.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organoheterocyclic compounds
Class Pyrrolidines
Subclass Pyrrolidones
Intermediate Tree Nodes Not available
Direct Parent Maleimides
Alternative Parents N-substituted carboxylic acid imides  Pyrrolines  Dicarboximides  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular Framework Aliphatic heteromonocyclic compounds
Substituents Maleimide - Carboxylic acid imide, n-substituted - Carboxylic acid imide - Dicarboximide - Pyrroline - Azacycle - Carboxylic acid derivative - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Carbonyl group - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Aliphatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as maleimides. These are compounds containing a 2,5-pyrroledione moiety.
External Descriptors a small molecule

Associated Targets(Human)

TYMS Tclin Thymidylate synthase (1651 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALB Tchem Serum albumin (2651 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HEK293 (82097 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
NCI-H460 (60772 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SF-268 (49410 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MGLL Tchem Monoglyceride lipase (1909 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
BLM Tchem Bloom syndrome protein (4248 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
THPO Tbio Thrombopoietin (834 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
IDE Tchem Insulin-degrading enzyme (806 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MPHOSPH8 Tbio M-phase phosphoprotein 8 (656 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ATG4B Tchem Cysteine protease ATG4B (985 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ANXA2 Tbio Annexin A2 (15 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SENP1 Tchem Sentrin-specific protease 1 (681 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
USP7 Tchem Ubiquitin carboxyl-terminal hydrolase 7 (837 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SENP2 Tchem Sentrin-specific protease 2 (79 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MEST Tbio Mesoderm-specific transcript homolog protein (25 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Nannizzia gypsea (2039 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Aspergillus flavus (8875 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Aspergillus niger (16508 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Saccharomyces cerevisiae (19171 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Aspergillus fumigatus (16427 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida tropicalis (8381 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trichophyton rubrum (3646 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mus musculus (284745 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Npsr1 Neuropeptide S receptor (260 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Trichophyton mentagrophytes (4846 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Mboat4 Ghrelin O-acyltransferase (37 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
crtY Lycopene cyclase (9 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504750765
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504750765
IUPAC Name 1-ethylpyrrole-2,5-dione
INCHI InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
InChIKey HDFGOPSGAURCEO-UHFFFAOYSA-N
Smiles CCN1C(=O)C=CC1=O
Isomeric SMILES CCN1C(=O)C=CC1=O
WGK Germany 3
RTECS UX9625000
Alternate CAS 25668-22-8,128-53-0,25668-22-8
NSC Number 7638
UN Number 2928
MeSH Entry Terms Ethylmaleimide;N Ethylmaleimide;N-Ethylmaleimide
Molecular Weight 125.13
Beilstein 112448
Reaxy-Rn 112448
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=112448&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

26 results found

Lot Number Certificate Type Date Item
G2509547 Certificate of Analysis Jul 02, 2025 E100553
G2509548 Certificate of Analysis Jul 02, 2025 E100553
F2525015 Certificate of Analysis Apr 26, 2025 E100553
E2507342 Certificate of Analysis Apr 26, 2025 E100553
E2507343 Certificate of Analysis Apr 26, 2025 E100553
E2507344 Certificate of Analysis Apr 26, 2025 E100553
E2507315 Certificate of Analysis Apr 26, 2025 E100553
A2517231 Certificate of Analysis Jan 07, 2025 E100553
A2417231 Certificate of Analysis Jan 07, 2025 E100553
A2517230 Certificate of Analysis Jan 07, 2025 E100553
A2517232 Certificate of Analysis Jan 07, 2025 E100553
A2517233 Certificate of Analysis Jan 07, 2025 E100553
C2303492 Certificate of Analysis Dec 17, 2024 E100553
C2303493 Certificate of Analysis Dec 17, 2024 E100553
C2303491 Certificate of Analysis Dec 17, 2024 E100553
C2303745 Certificate of Analysis Dec 12, 2024 E100553
C2303730 Certificate of Analysis Dec 12, 2024 E100553
C2303497 Certificate of Analysis Dec 12, 2024 E100553
C2303494 Certificate of Analysis Dec 12, 2024 E100553
F2214553 Certificate of Analysis Mar 18, 2024 E100553
F2202028 Certificate of Analysis Mar 18, 2024 E100553
F2214551 Certificate of Analysis Mar 18, 2024 E100553
F2214552 Certificate of Analysis Mar 18, 2024 E100553
K2110381 Certificate of Analysis Aug 02, 2023 E100553
I2404031 Certificate of Analysis Nov 25, 2022 E100553
F2202029 Certificate of Analysis Feb 14, 2022 E100553

Show more⌵

Chemical and Physical Properties

Solubility Soluble in ethanol, water, chloroform, methanol and toluene.
Sensitivity Light,Heat,Air Sensitive.
Flash Point(°F) 163.4℉
Flash Point(°C) 73°C
Boil Point(°C) 210°C
Melt Point(°C) 43-46°C
Molecular Weight 125.130 g/mol
XLogP3 0.900
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 1
Exact Mass 125.048 Da
Monoisotopic Mass 125.048 Da
Topological Polar Surface Area 37.400 Ų
Heavy Atom Count 9
Formal Charge 0
Complexity 165.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Citations of This Product

1. Guo-Qi Zhang, Wei-ping Liu, Yu-Han Shi, Yu-Xian Zou, Li-Yao Xu, Hui-Ling Cheng, Tao Wang, Wen-Bin Li, Yan Zhao, Zhi-Hong Xu.  (2024)  Intrinsic peroxidase activity of carbon dots derived from expired drugs and its application in automatic detection of total antioxidant capacity.  MICROCHEMICAL JOURNAL,  197  (109720). 
2. Gao Lifang, Chen Rong, Li Haixia, Xu Dan, Zheng Danning.  (2023)  Time-resolved fluorescence nanoprobe of acetylcholinesterase based on ZnGeO:Mn luminescence nanorod modified with metal ions.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (29): (7047-7055). 
3. Li Huang, Shangying Qin, Kun Yang, Yuanjin Xu, Xiaocui Wu, Zhongwei Lin, Yilin Wang.  (2024)  Dual signal AA detection based on fluorescence and local surface plasmon resonance absorption technology.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  306  (123570). 
4. Jia Chen, Shengrong Yu, Zhiling Qian, Kangdi He, Bingqian Li, Yuting Cao, Keqi Tang, Shengjia Yu, Yong-Xiang Wu.  (2023)  Target-triggered enzyme-free amplification for highly efficient AND-gated bioimaging in living cells.  ANALYST,     
5. Ruiling Li, Na Wu, Hui Xue, Binghong Gao, Huilan Liu, Tianfeng Han, Xiaobo Hu, Yonggang Tu, Yan Zhao.  (2023)  Influence and effect mechanism of disulfide bonds linkages between protein-coated lipid droplets and the protein matrix on the physicochemical properties, microstructure, and protein structure of ovalbumin emulsion gels.  COLLOIDS AND SURFACES B-BIOINTERFACES,  223  (113182). 
6. Xu Yang, Maosheng Lin, Jirui Wei, Jing Sun.  (2023)  A self-crosslinking nanogel scaffold for enhanced catalytic efficiency and stability.  Polymer Chemistry,  14  (3): (284-294). 
7. Shaoxiong Wu, Lianyuan Wang, Haiyan Zhu, Jing Liang, Liang Ge, Cong Li, Ting Miao, Jian Li, Zhenxing Cheng.  (2022)  Catalytic degradation of CWAs with MOF-808 and PCN-222: Toward practical application.  JOURNAL OF CHEMICAL RESEARCH,     
8. Yu Wang, Yu Xue, Qilin Zhao, Shuang Wang, Jian Sun, Xiurong Yang.  (2022)  Colorimetric Assay for Acetylcholinesterase Activity and Inhibitor Screening Based on Metal–Organic Framework Nanosheets.  ANALYTICAL CHEMISTRY,  94  (47): (16345–16352). 
9. Zhenyu Ding, Zhe Li, Xiaoxue Zhao, Yanrong Miao, Zhenfeng Yuan, Yuanyuan Jiang, Yizhong Lu.  (2023)  Self-deposited ultrasmall Ru nanoparticles on carbon nitride with high peroxidase-mimicking activity for the colorimetric detection of alkaline phosphatase.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,  631  (86). 
10. Zhiwen Gan, Tian Zhang, Xuanxuan An, Qin Tan, Shujun Zhen, Yongmei Hu, Xiaoli Hu.  (2022)  Dual enzyme-mimicking fluorescent amino terephthalic acid/CuFe/adenosine triphosphate nanoparticles for determination of H2O2 and ascorbic acid.  MICROCHEMICAL JOURNAL,  182  (107939). 
11. Caizhen Liang, Xiaobao Xie, Dandan Zhang, Jin Feng, Shunying Lu, Qingshan Shi.  (2021)  Biomass carbon dots derived from Wedelia trilobata for the direct detection of glutathione and their imaging application in living cells.  Journal of Materials Chemistry B,  (28): (5670-5681). 
12. Haiyang Yao, Difei Jiang, Gaoqiu Dong, Jiamin Sun, Shasha Sun, Lingling Li, Fenfen Zheng, Weiwei Xiong.  (2021)  Near infrared imaging of intracellular GSH by AuNCs@MnO2 core–shell nanoparticles based on the absorption competition mechanism.  ANALYST,  146  (16): (5115-5123). 
13. Selvaraj Muthusamy, Long Zhao, Kanagaraj Rajalakshmi, Dongwei Zhu, Rodah Soy, John Mack, Tebello Nyokong, Shengjun Wang, Kang-Bong Lee, Weihua Zhu.  (2021)  Turn-on detection of cysteine by a donor-acceptor type quinoline fluorophore: Exploring the sensing strategy and performance in bioimaging.  DYES AND PIGMENTS,  193  (109556). 
14. Yan Bingsong, Liu Wendong, Duan Guangbin, Ni Pengjuan, Jiang Yuanyuan, Zhang Chenghui, Wang Bo, Lu Yizhong, Chen Chuanxia.  (2021)  Colorimetric detection of acetylcholinesterase and its inhibitor based on thiol-regulated oxidase-like activity of 2D palladium square nanoplates on reduced graphene oxide.  MICROCHIMICA ACTA,  188  (5): (1-9). 
15. Xiaolin Yang, Chenggang Long, Yaozong Tan, Qianming Wang.  (2021)  Surface recognition strategy via ascorbic acid-triggered decomposition of boron nitride-loaded cobalt oxyhydroxide nanosheets.  JOURNAL OF ALLOYS AND COMPOUNDS,  872  (159625). 
16. Fuming Sang, Menglin Li, Suyao Yin, Huahua Shi, Yan Zhao, Zhizhou Zhang.  (2021)  Highly sensitive and selective detection and intracellular imaging of glutathione using MnO2 nanosheets assisted enhanced fluorescence of gold nanoclusters.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  256  (119743). 
17. Ying-Jie Tang, Wen-Le Fang, Kui Ren, Xiao-Feng Guo, Hong Wang.  (2021)  A turn-on homodimer fluorescent probe based on homo-FRET for the sensing of biothiols in lysosome: a trial of a new turn-on strategy.  ANALYST,  146  (9): (2974-2982). 
18. Bangrong Cai, Mengya Liu, Jinxing Li, Dujuan Xu, Jiansheng Li.  (2021)  Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells.  FOOD AND CHEMICAL TOXICOLOGY,  150  (112050). 
19. Kuanxia Ma, Lushan Liang, Xie Zhou, Weiguo Tan, Ou Hu, Zuanguang Chen.  (2021)  A Redox-induced Dual-mode Colorimetric and Fluorometric Method based on N-CDs and MnO2 for Determination of Isoniazid in Tablets and Plasma Samples.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  247  (119097). 
20. Lan Guo, Ya-Jie Zhang, Yong-Liang Yu, Jian-Hua Wang.  (2020)  In Situ Generation of Prussian Blue by MIL-53 (Fe) for Point-of-Care Testing of Butyrylcholinesterase Activity Using a Portable High-Throughput Photothermal Device.  ANALYTICAL CHEMISTRY,  92  (21): (14806–14813). 
21. Xiaobin Zhou, Mengke Wang, Junyang Chen, Xiaolei Xie, Xingguang Su.  (2020)  Peroxidase-like activity of Fe–N–C single-atom nanozyme based colorimetric detection of galactose.  ANALYTICA CHIMICA ACTA,  1128  (72). 
22. Wei Cheng, Xuqi Xue, Fang Zhang, Baoxin Zhang, Taihan Li, Liang Peng, Dong-Hyung Cho, Hongli Chen, Jianguo Fang, Xingguo Chen.  (2020)  A novel AIEgen-based probe for detecting cysteine in lipid droplets.  ANALYTICA CHIMICA ACTA,  1127  (20). 
23. Feifei Li, Yajie Yu, Fubing Xiao, Hao Liang, Can Liu, Pengfei Fan, Shengyuan Yang.  (2020)  Colorimetric strategy for ascorbic acid detection based on the oxidase-like activity of silver nanoparticle single-walled carbon nanotube composites.  LUMINESCENCE,  35  (7): (1084-1091). 
24. Caixue Lin, Hailu He, Yongqi Zhang, Mingyue Xu, Feng Tian, Ling Li, Yingxi Wang.  (2020)  Acetaldehyde-modified-cystine functionalized Zr-MOFs for pH/GSH dual-responsive drug delivery and selective visualization of GSH in living cells.  RSC Advances,  10  (6): (3084-3091). 
25. Bo-Hui Huang, San-San Shen, Na Wei, Xiao-Feng Guo, Hong Wang.  (2020)  Fluorescence biosensor based on silicon quantum dots and 5,5′-dithiobis-(2-nitrobenzoic acid) for thiols in living cells.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  229  (117972). 
26. Pang Lan-Fang, Wu Hao, Fu Meng-Jie, Guo Xiao-Feng, Wang Hong.  (2019)  Red emissive boron and nitrogen co-doped “on-off-on” carbon dots for detecting and imaging of mercury(II) and biothiols.  MICROCHIMICA ACTA,  186  (11): (1-9). 
27. Zhihao Wu, Danyang Nan, Huan Yang, Shuang Pan, Hui Liu, Xiaoli Hu.  (2019)  A ratiometric fluorescence-scattered light strategy based on MoS2 quantum dots/CoOOH nanoflakes system for ascorbic acid detection.  ANALYTICA CHIMICA ACTA,  1091  (59). 
28. Qian Yang, Xiaoyan Wang, Hailong Peng, Maryam Arabi, Jinhua Li, Hua Xiong, Jaebum Choo, Lingxin Chen.  (2020)  Ratiometric fluorescence and colorimetry dual-mode assay based on manganese dioxide nanosheets for visual detection of alkaline phosphatase activity.  SENSORS AND ACTUATORS B-CHEMICAL,  302  (127176). 
29. Pengjuan Ni, Chuanxia Chen, Yuanyuan Jiang, Chenghui Zhang, Bo Wang, Bingqiang Cao, Cuncheng Li, Yizhong Lu.  (2019)  Gold nanoclusters-based dual-channel assay for colorimetric and turn-on fluorescent sensing of alkaline phosphatase.  SENSORS AND ACTUATORS B-CHEMICAL,  301  (127080). 
30. Heng Zhang, Zhen Wang, Xiaoqing Yang, Zi-Long Li, Linhao Sun, Jimei Ma, Hong Jiang.  (2019)  The determination of α-glucosidase activity through a nano fluorescent sensor of F-PDA−CoOOH.  ANALYTICA CHIMICA ACTA,  1080  (170). 
31. Jiapei Gu, Xiangqian Li, Zhan Zhou, Wanqiang Liu, Kai Li, Jinwei Gao, Ying Zhao, Qianming Wang.  (2019)  2D MnO2 nanosheets generated signal transduction with 0D carbon quantum dots: synthesis strategy, dual-mode behavior and glucose detection.  Nanoscale,  11  (27): (13058-13068). 
32. Qing He, Ruixi Li, Zhenwei Yuan, Habtamu Kassaye, Jinrong Zheng, Chen Wei, Fei Wang, Yuxin Yao, Lijuan Gui, Haiyan Chen.  (2019)  A turn-on near-infrared fluorescent probe for detection of cysteine over glutathione and homocysteine in vivo.  Analytical Methods,  11  (14): (1857-1867). 
33. Junlin Sun, Feng Liu, Wenqian Yu, Qunying Jiang, Jialing Hu, Yahua Liu, Fuan Wang, Xiaoqing Liu.  (2019)  Highly sensitive glutathione assay and intracellular imaging with functionalized semiconductor quantum dots.  Nanoscale,  11  (11): (5014-5020). 
34. Ping Chen, Hui Zhong, Xiang Wang, Changdong Shao, Sanjun Zhi, Xiao-Rong Li, Changmei Wei.  (2019)  A label-free colorimetric strategy for facile and low-cost sensing of ascorbic acid using MnO2 nanosheets.  Analytical Methods,  11  (11): (1469-1474). 
35. Yu Jiani, Yang Weitao, Xing Shige, Wang Jun, Han Huanxing, Zhang Pengfei, Xiang Chenyang, Zhang Bingbo.  (2019)  Blended gold/MnO2@BSA nanoparticles for fluorometric and magnetic resonance determination of ascorbic acid.  MICROCHIMICA ACTA,  186  (2): (1-9). 
36. Wenxiang Xu, Jingqin Chen, Shan Sun, Zhongdi Tang, Kai Jiang, Liang Song, Yuhui Wang, Chengbo Liu, Hengwei Lin.  (2018)  Fluorescent and photoacoustic bifunctional probe for the detection of ascorbic acid in biological fluids, living cells and in vivo.  Nanoscale,  10  (37): (17834-17841). 
37. Linlin Hu, Xing Wei, Jie Meng, Xiaoyan Wang, Xuwei Chen, Jianhua Wang.  (2018)  Acetaldehyde-modified-cystine as an enhanced fluorescent probe for intracellular glutathione imaging.  SENSORS AND ACTUATORS B-CHEMICAL,  268  (264). 
38. Xue Qin, Cao Xuanyu, Zhang Cuiling, Xian Yuezhong.  (2018)  Polydopamine nanodots are viable probes for fluorometric determination of the activity of alkaline phosphatase via the in situ regulation of a redox reaction triggered by the enzyme.  MICROCHIMICA ACTA,  185  (4): (1-9). 
39. Yuefang Hu, Liangliang Zhang, Xuefeng Li, Rongjun Liu, Liyun Lin, Shulin Zhao.  (2017)  Green Preparation of S and N Co-Doped Carbon Dots from Water Chestnut and Onion as Well as Their Use as an Off–On Fluorescent Probe for the Quantification and Imaging of Coenzyme A.  ACS Sustainable Chemistry & Engineering,  (6): (4992–5000). 
40. Yun Zhao, Yuanyuan Xue, Haoyang Li, Ruitao Zhu, Yuehong Ren, Qinghua Shi, Song Wang, Wei Guo.  (2017)  An excited state intramolecular proton transfer dye based fluorescence turn-on probe for fast detection of thiols and its applications in bioimaging.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  175  (215). 
41. Cong Luo, Jin Sun, Bingjun Sun, Dan Liu, Lei Miao, Tyler Jay Goodwin, Leaf Huang, Zhonggui He.  (2016)  Facile Fabrication of Tumor Redox-Sensitive Nanoassemblies of Small-Molecule Oleate Prodrug as Potent Chemotherapeutic Nanomedicine.  Small,  12  (46): (6353-6362). 
42. Jingjing Zhao, Kun Zhang, Ji Ji, Baohong Liu.  (2016)  Sensitive and label-free quantification of cellular biothiols by competitive surface-enhanced Raman spectroscopy.  TALANTA,  152  (196). 
43. Yan-Yun Li, Xiao-Qin Jiang, Ling-Fei Lu, Min Zhang, Guoyue Shi.  (2016)  “Molecular beacon”-hosted thioflavin T: Applications for label-free fluorescent detection of iodide and logic operations.  TALANTA,  150  (615). 
44. Qing Jin, Yan Li, Jianzhong Huo, Xiaojun Zhao.  (2016)  The “off–on” phosphorescent switch of Mn-doped ZnS quantum dots for detection of glutathione in food, wine, and biological samples.  SENSORS AND ACTUATORS B-CHEMICAL,  227  (108). 
45. Ye Tian, Man Wu, Xiangxiang Liu, Zhi Liu, Quan Zhou, Zhongwei Niu, Yong Huang.  (2014)  Probing the Endocytic Pathways of the Filamentous Bacteriophage in Live Cells Using Ratiometric pH Fluorescent Indicator.  Advanced Healthcare Materials,  (3): (413-419). 
46. Ling Chen, Jinhua Li, Shasha Wang, Wenhui Lu, Aiguo Wu, Jaebum Choo, Lingxin Chen.  (2014)  FITC functionalized magnetic core–shell Fe3O4/Ag hybrid nanoparticle for selective determination of molecular biothiols.  SENSORS AND ACTUATORS B-CHEMICAL,  193  (857). 
47. Li-Pei Zhang, Bo Hu, Jian-Hua Wang.  (2012)  Label-free colorimetric sensing of ascorbic acid based on Fenton reaction with unmodified gold nanoparticle probes and multiple molecular logic gates.  ANALYTICA CHIMICA ACTA,  717  (127). 
48. Ruiqi Huang, Yingfeng Qin, Yanqin Huang, Zengqiong Huang, Gao-Jie Ye.  (2024)  A convenient smartphone-assisted colorimetric for 6-Mercaptopurine detection using enhanced oxidase-like activity of β-cyclodextrin modified MnO2 nanosheets.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  318  (124493). 
49. Yilan Zhao, Xue Jiang, Ke Huang, Xiaoli Xiong, Qing Yang.  (2025)  A smartphone-integrated ratiometric fluorescent sensor for ascorbic acid determination using microplasma-enabled carbon dots and rhodamine B.  FOOD CHEMISTRY,  463  (141280). 
50. Aoran Huang, Jianyun Rao, Xin Feng, Xingru Li, Tianhua Xu, Li Yao.  (2024)  Breaking New Ground: Unraveling the USP1/ID3/E12/P21 Axis in Vascular Calcification.  Translational Research,     
51. Yiting Jiang, Zhejie Chen, Yating Yuan, Linxin Tian, Chuhuang Dong, Wencheng Shen, Jinchao Wei, Shengpeng Wang, Yu Yang, Jia Ge.  (2024)  Cu–N–C single-atom nanozyme as an ultrasensitive sensing platform for α-glucosidase detection.  Materials Today Chemistry,  41  (102327). 
52. Yuxia Li, Min Li, Liuzhi Hu, Baozhu Zhang.  (2024)  Fluorescence Sensors for the Detection of L-Histidine Based on Silver Nanoclusters Modulated by Copper Ions.  MOLECULES,  29  (10): (2167). 
53. Yujing He, Jing Hu, Siqi Wei, Chenghui Li, Xiandeng Hou.  (2024)  Label-free and sensitive assay for ICP-MS determination of alkaline phosphatase activity via manganese target.  MICROCHEMICAL JOURNAL,  200  (110342). 
54. Jinsong Wang, Farzad Seidi, Xiaotong Shi, Chengcheng Li, Yang Huang, Huining Xiao.  (2024)  Lignin self-healing coatings based on thermo-reversible Diels-Alder reaction for anticorrosion applications.  PROGRESS IN ORGANIC COATINGS,  191  (108428). 
55. Bei Li, Xiaoran Zhang, Xincheng Sun, Peng Lei, Ruyu Li, Chuan Dong, Shaomin Shuang.  (2025)  Polypyrrole@MnO2 fluorescence nanocomposites as a multifunctional architecture for glutathione sensing and synergistic therapy of cancer.  MICROCHEMICAL JOURNAL,  209  (112852). 
56. Yu Ji, Suchen Qu, Gaoyu Shi, Liansheng Fan, Jing Qian, Zhaorui Sun, Feng Lu, Xin Han.  (2024)  Triggered Cascade-Activation Nanoplatform to Alleviate Hypoxia for Effective Tumor Immunotherapy Guided by NIR-II Imaging.  ACS Nano,  18  (45): (31421-31434). 
57. Jinsong Wang, Farzad Seidi, Xiaotong Shi, Chengcheng Li, Yang Huang, Huining Xiao.  (2025)  Unveiling the potential of dual-extrinsic/intrinsic self-healing lignin-based coatings for anticorrosion applications.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  285  (138073). 

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.