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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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N646485-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$200.90
|
|
|
N646485-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$420.90
|
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Saccharides Monosaccharides
| Specifications & Purity | ≥97% |
|---|---|
| Biochemical and Physiological Mechanisms | n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research. |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research In Vitro n-Butyl-β-D-fructofuranoside (0-23.6 μg/mL; 24-78 hours) has antiproliferation activity and inhibits the viability of Bel-7402 cells. n-Butyl-β-D-fructofuranoside (0-75 μg/mL; 0-72 hours) inhibits BEL-7402 cells by interfering with cell cycle and inducing apoptosis. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: Bel-7402 cells Concentration: 0.47, 2.95, 5.90, 11.8, 17.7 and 23.6 μg/mL Incubation Time: 24, 48 and 72 hours Result: Inhibited the proliferation of Bel-7402 cells at both time- and dose-dependent manner. Cell Cycle AnalysisCell Line: Bel-7402 cells Concentration: 0, 50 and 75 μg/mL Incubation Time: 24, 48 and 72 hours Result: Induced cell cycle arrest at G0/G1 phase. Western Blot AnalysisCell Line: Bel-7402 cells Concentration: 23.6 μg/mL Incubation Time: 0, 24, 48 and 72 hours Result: Decreased Bcl-2 and increased Bax and p53 levels in a time manner. Form:Oil IC50& Target:Bax Bcl-2 |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Smiles | CCCCO[C@]1([C@H]([C@@H]([C@H](O1)CO)O)O)CO |
|---|---|
| Isomeric SMILES | CCCCO[C@]1([C@H]([C@@H]([C@H](O1)CO)O)O)CO |
| PubChem CID | 13386213 |
| Molecular Weight | 236.26 |
| Solubility | DMSO : 100 mg/mL (423.26 mM; Need ultrasonic) |
|---|---|
| Molecular Weight | 236.260 g/mol |
| XLogP3 | -0.500 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 6 |
| Exact Mass | 236.126 Da |
| Monoisotopic Mass | 236.126 Da |
| Topological Polar Surface Area | 99.400 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 211.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |