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Mps1-IN-1 dihydrochloride - ≥98%(HPLC), high purity , CAS No.1883548-93-3

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 1883548-93-3
Molecular Weight: 608.58
PubChem CID: 91691119

In stock

Item Number

M287223

Grouped product items
SKU	Size	Availability	Price
M287223-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$296.90
M287223-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,333.90
M287223-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$6,002.90

Selective Mps1 kinase inhibitor

View related series

Cell Cycle (2830) Cell Cycle/DNA Damage (2602) Cytoskeleton (498) Mps1 (16)

Basic Description

Synonyms	1-[3-Methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol dihydrochloride
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50= 367 nM); exhibits >1000 fold-selectivity against a panel of 352 kinases with the exceptions of ALK and Ltk. Disrupts the recruitment of Mad2 to kinetochores. Increases frequency of multipolar mi
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

IUPAC Name	1-[3-methoxy-4-[[4-(2-propan-2-ylsulfonylanilino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]piperidin-4-ol;dihydrochloride
INCHI	InChI=1S/C28H33N5O4S.2ClH/c1-18(2)38(35,36)26-7-5-4-6-23(26)30-24-17-27(32-28-21(24)10-13-29-28)31-22-9-8-19(16-25(22)37-3)33-14-11-20(34)12-15-33;;/h4-10,13,16-18,20,34H,11-12,14-15H2,1-3H3,(H3,29,30,31,32);2*1H
InChIKey	HFJLUXGXTPNYTQ-UHFFFAOYSA-N
Smiles	CC(C)S(=O)(=O)C1=CC=CC=C1NC2=CC(=NC3=C2C=CN3)NC4=C(C=C(C=C4)N5CCC(CC5)O)OC.Cl.Cl
Isomeric SMILES	CC(C)S(=O)(=O)C1=CC=CC=C1NC2=CC(=NC3=C2C=CN3)NC4=C(C=C(C=C4)N5CCC(CC5)O)OC.Cl.Cl
PubChem CID	91691119
Molecular Weight	608.58

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 60.86, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 60.86, Max Conc. mM: 100

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